Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gaojie Song"'
Autor:
Chaoyu Fu, Wenmao Huang, Qingnan Tang, Minghui Niu, Shiwen Guo, Tobias Langenhan, Gaojie Song, Jie Yan
Adhesion G protein-coupled receptors (aGPCRs) are a large family within the superfamily of G protein-coupled receptors involved in various physiological processes. One unique feature of aGPCRs is their long N-terminal extracellular regions (ECRs), wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e586436388bf69a583aef786bef1d41
https://doi.org/10.1101/2023.03.14.532526
https://doi.org/10.1101/2023.03.14.532526
Autor:
Liang Chen, Shun Zhang, Niannian Xue, Mengjia Hong, Xiaohui Zhang, Dan Zhang, Jing Yang, Sijia Bai, Yifan Huang, Haowei Meng, Hao Wu, Changming Luan, Biyun Zhu, Gaomeng Ru, Meizhen Liu, Mingyao Liu, Yiyun Cheng, Chengqi Yi, Gaojie Song, Liren Wang, Dali Li
Adenine base editors (ABEs) catalyze A-to-G transitions showing broad applications, but their bystander mutations and off-target editing effects raise the concerns of safety issues. Through structure-guided engineering, we found ABE8e with an N108Q m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4dd15a8163cf61d2da15964b4b0aeaf
https://doi.org/10.1101/2022.08.12.503700
https://doi.org/10.1101/2022.08.12.503700
Previously we reported a common activation pathway of the class A G protein-coupled receptors (GPCRs) in which a series of conserved residues/motifs undergo conformational change during extracellular agonist binding and finally induce the coupling of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1161f9e6a8086ef9b8e6fe31b33b29d
https://doi.org/10.1101/2021.09.08.459393
https://doi.org/10.1101/2021.09.08.459393
Autor:
Chafen Lu, Timothy A. Springer, Juan Feng, Gaojie Song, Emma Garst, Flaminia Catteruccia, Kristin Beale, Emily Lund, Jiabin Yan
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0216260 (2020)
PLoS ONE
PLoS ONE
The circumsporozoite protein (CSP) and thrombospondin-related adhesion protein (TRAP) are major targets for pre-erythrocytic malaria vaccine development. However, the most advanced CSP-based vaccine RTS,S provides only partial protection, highlightin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa1c72cdaaa085f7df2c32f0c760e33