Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Doron Merkler"'
Autor:
Andreas Agrafiotis, Raphael Dizerens, Ilena Vincenti, Ingrid Wagner, Raphael Kuhn, Danielle Shlesinger, Marcos Manero-Carranza, Tudor-Stefan Cotet, Kai-Lin Hong, Nicolas Page, Nicolas Fonta, Ghazal Shammas, Alexandre Mariotte, Margot Piccinno, Mario Kreutzfeldt, Benedikt Gruntz, Roy Ehling, Alessandro Genovese, Alessandro Pedrioli, Andreas Dounas, Sören Franzenburg, Vladyslav Kavaka, Lisa Ann Gerdes, Klaus Dornmair, Eduardo Beltrán, Annette Oxenius, Sai T. Reddy, Doron Merkler, Alexander Yermanos
B cells contribute to the pathogenesis of both cellular- and humoral-mediated central nervous system (CNS) inflammatory diseases through a variety of mechanisms. In such conditions, B cells may enter the CNS parenchyma and contribute to local tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4b738ca1916f7c14ffa7b38c87dcd9f
https://doi.org/10.1101/2022.08.29.505678
https://doi.org/10.1101/2022.08.29.505678
Autor:
Thomas Gruber, Nicolas Page, Aaron J. Johnson, Armelle Klopstein, Vivianne M. Schallenberg, Javier R. Pareja, Urban Deutsch, Sidar Aydin, Elisa Kaba, Britta Engelhardt, Doron Merkler, Mirjam Schenk
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8+T cells are found in MS lesions and antigen (Ag)-presentation at the BBB was pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::846ca216210c4b2599834376fd42c3b6
https://doi.org/10.1101/2021.10.12.464035
https://doi.org/10.1101/2021.10.12.464035
Autor:
Noushin Hadadi, Doron Merkler, Gabriela Salinas, Martina Spiljar, Karin Steinbach, Mirko Trajkovski
Cold exposure is an extensively used intervention for enhancing thermogenic and mitochondrial activity in adipose tissues. As such, it has been suggested as a potential lifestyle intervention for body weight maintenance. The metabolic consequences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85620d17e5cc9f45648663681b7a1bd
https://doi.org/10.1101/2021.03.26.437139
https://doi.org/10.1101/2021.03.26.437139
Autor:
Alessandro Genovese, Laura Hauri, Alexander Yermanos, Damiano Robbiani, Daniel Neumeier, Sai T. Reddy, Alessandro Pedrioli, Ioana Sandu, Doron Merkler, Chrysa Papadopoulou, Lucia Csepregi, Victor Greiff, Raphael Kuhn, Annette Oxenius, Roy A. Ehling, Andreas Agrafiotis, Jiami Han, Kai-Lin Hong
Plasma cells and their secreted antibodies play a central role in the long-term protection against chronic viral infection. However, due to experimental limitations, a comprehensive description of linked genotypic, phenotypic, and antibody repertoire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5faf7ef504a0608382fadd0dc6cc81c2
https://doi.org/10.1101/2021.01.29.428852
https://doi.org/10.1101/2021.01.29.428852
Autor:
Mario Kreutzfeldt, Melanie Greter, Doron Merkler, Ingrid Wagner, Noushin Hadadi, Ilena Vincenti, Mary-Aude Rochat, Martina Spiljar, Nicolas Page, Mirko Trajkovski, Ozren Stojanović, Matthias Mack, Bogna Klimek, Dilay Cansever, Claire Chevalier, Nicolas Suárez-Zamorano, Dorothée Rigo, Karin Steinbach
SUMMARYAutoimmunity is energetically costly, but the impact of a metabolically active state on immunity and immune-mediated diseases is unclear. Ly6Chi monocytes are key effectors in CNS autoimmunity with elusive role in priming naïve autoreactive T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4bc2a547c16771095b00097357fbad
https://doi.org/10.1101/2020.08.28.269563
https://doi.org/10.1101/2020.08.28.269563
Autor:
Dimitry Ofengeim, Fred Wolf, Emily M. Ullrich Gavilanes, Nicolas Snaidero, Tradite Neziraj, Nellwyn Hagan, Thomas Misgeld, Lisa Woodworth, Eduardo Beltrán, Juan Daniel Flórez Weidinger, Joseph Gans, Ruben Portugues, Adrian-Minh Schumacher, Mehrnoosh Jafari, Martin Kerschensteiner, Stephanie S. Schmidt, Tanja Jürgens, Doron Merkler, Mario Kreutzfeldt
SUMMARYCortical pathology contributes to chronic cognitive impairment of patients suffering from the neuroinflammatory disease multiple sclerosis (MS). How such gray matter inflammation affects neuronal structure and function is not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a0d61e55c15ba450d643f7c621a0a6
https://doi.org/10.1101/758193
https://doi.org/10.1101/758193
Autor:
Nicolas Page, Flavian Thelen, Xenia Ficht, Doron Merkler, Christoph Schlapbach, Nora Ruef, Francesca Barone, Oliver T. Fackler, Federica Moalli, V. V. G. K. Inavalli, Jens V. Stein, James Sharpe, U. V. Nägerl, Matteo Iannacone, Andrea Raimondi, Bettina Stolp, Lukas M. Altenburger, Matthias S. Dettmer, Philipp Germann, Kirsten A. Keyser, Seyed Morteza Seyed Jafari
Tissue macrophages and tissue resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. To date, it is incompletely understood how these two cell types cooperate for efficient organ surveill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2dde24631f757e36490c515352e952
https://doi.org/10.1101/723791
https://doi.org/10.1101/723791
In vivo function of the lipid raft protein Flotillin 1 during CD8+ T cell-mediated host surveillance
Autor:
Federica Moalli, Doron Merkler, Nora Ruef, Bettina Stolp, Nicolas Page, Xenia Ficht, Alba Diz-Muñoz, Verena Niggli, Jens V. Stein, Ben J. Nichols
Flotillin-1 (Flot1) is a highly conserved, ubiquitously expressed lipid raft-associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired due to a decrease in myosin II-mediated contractility. Flot1 also accumulates in the uro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca731df683f0fbb90c9b0d2918157eaa
https://doi.org/10.1101/403592
https://doi.org/10.1101/403592