Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Christoph Kellendonk"'
Autor:
Kelly M. Martyniuk, Arturo Torres-Herraez, Marcelo Rubinstein, Marie A. Labouesse, Christoph Kellendonk
In the striatum, acetylcholine (ACh) neuron activity is modulated co-incident with dopamine (DA) release in response to unpredicted rewards and reward predicting cues and both neuromodulators are thought to regulate each other. While this co-regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49845b85f10bd3c52c60b09d7b0af8a8
https://doi.org/10.1101/2021.12.08.471871
https://doi.org/10.1101/2021.12.08.471871
Autor:
Eduardo F. Gallo, Christoph Kellendonk, Kelly M. Martyniuk, Eric Teboul, Yulong Li, Jonathan A. Javitch, Peter D. Balsam, Julia E. Greenwald
Cholinergic interneurons (CINs) in the striatum respond to salient stimuli with a multiphasic response, including a pause, in neuronal activity. Slice physiology experiments have shown the importance of dopamine D2 receptors (D2Rs) in regulating CIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f0d180906f650d1ef97e80814fe6c42
https://doi.org/10.1101/2020.09.07.284612
https://doi.org/10.1101/2020.09.07.284612
Ventral striatal dopamine is thought to be important for associative learning. Dopamine exerts its role via activation of dopamine D1 and D2 receptors in the ventral striatum. Upregulation of dopamine D2R in the indirect pathway of the nucleus accumb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748be9edd2552e9b6f57daad8f69e218
https://doi.org/10.1101/2020.04.28.066670
https://doi.org/10.1101/2020.04.28.066670
Autor:
Karlla W. Brigatti, Christoph Kellendonk, Bianca Migliori, Giuseppe P. Cortese, Bin Xu, Yan Sun, Barbara Corneo, Sander Markx, Jonathan A. Javitch, Kevin A. Strauss, Ceyda Llapashtica, Frank A. Provenzano, Steven A. Kushner, Job O. de Jong
Autism spectrum disorder (ASD) represents a major public health burden but translating promising treatment findings from preclinical non-human models of ASD to the clinic has remained challenging. The recent development of forebrain organoids generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0993f1703895af7a766bef36be5bfb
https://doi.org/10.1101/739391
https://doi.org/10.1101/739391
Autor:
Paul E. M. Phillips, Gaël Malleret, Vanessa Winiger, Scott Ng-Evans, Julia Morud, Mary Elizabeth Bach, H. Jonathan Polan, Eleanor H. Simpson, Dominik Biezonski, Christoph Kellendonk, Judy P. Zhu, Eric R. Kandel
Publikováno v:
Learning & Memory. 21:205-214
A common genetic polymorphism that results in increased activity of the dopamine regulating enzyme COMT (the COMT Val158 allele) has been found to associate with poorer cognitive performance and increased susceptibility to develop psychiatric disorde
Autor:
Lukas Schwake, Andreas Reimann, Günther Schütz, Wolfgang Schmid, Holger M. Reichardt, Hartmut Beug, Christoph Kellendonk, Katharina Stangl, Daniel Gau, Christian Opherk, Andreas Hoeflich, Richard Moriggl, François Tronche
Publikováno v:
Genes & Development. 18:492-497
Mice carrying a hepatocyte-specific inactivation of the glucorticoid receptor (GR) gene show a dramatic reduction in body size. Growth hormone signaling mediated by the Stat5 transcription factors is impaired. We show that Stat5 proteins physically i