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Autor:
Hermes, Stephen, Cady, Janet, Armentrout, Steven, O’Connor, James, Carlson, Sarah, Cruchaga, Carlos, Wingo, Thomas, Greytak, Ellen McRae
Publikováno v:
medRxiv
BackgroundPolygenic risk scores (PRS) are linear combinations of genetic markers weighted by effect size that are commonly used to predict disease risk. For complex heritable diseases such as late onset Alzheimer’s disease (LOAD), PRS models fail t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349b69614ae65b9128b863459497ba0c
https://europepmc.org/articles/PMC9934790/
https://europepmc.org/articles/PMC9934790/