Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adrienne, Tin"'
Improved understanding of genetic regulation of proteome can facilitate the identification of causal mechanisms for complex traits. We analyzed data on 4,657 plasma proteins from 7,213 European American (EA) and 1,871 African American (AA) individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e68c4fd016dbcb6c1994acbf14b05123
https://doi.org/10.1101/2021.03.15.435533
https://doi.org/10.1101/2021.03.15.435533
Autor:
Aditya Surapaneni, Nilanjan Chatterjee, Dan E. Arking, Jingsha Chen, Josef Coresh, Adrienne Tin, Morgan E. Grams, Bing Yu, Anna Köttgen, Jin Jin, Linda Zhou, Zhi Yu, Ron C. Hoogeveen, Christie M. Ballantyne
Genome-wide association studies (GWAS) have revealed numerous loci for kidney function (estimated glomerular filtration rate, eGFR). The relationship of polygenic predictors of eGFR, risk of incident adverse kidney outcomes, and the plasma proteome i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe913060f97f41ae6004b93f935aedf7
https://doi.org/10.1101/2020.09.05.284265
https://doi.org/10.1101/2020.09.05.284265
Autor:
Eric Boerwinkle, Guanghao Qi, Josef Coresh, Adrienne Tin, Alexander Teumer, Cristian Pattaro, Anna Köttgen, Nilanjan Chatterjee, Harold Snieder, Morgan E. Grams, Zhi Yu
ObjectiveTo evaluate the bi-directional causal relation between kidney function and blood pressure.DesignMendelian randomisation study.SettingWe performed two-sample Mendelian randomisation analyses. Genetic instruments of kidney function traits were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ce176c4ef63e46e65111dfd45b0e1b
Autor:
Josef Coresh, Adrienne Tin, Penglong Wang, Eliseo Guallar, Charles E. Newcomb, Ryan J. Longchamps, Jan Bressler, Brian O'Rourke, Traci M. Bartz, Kent D. Taylor, Nona Sotoodehnia, Eric Boerwinkle, James S. Pankow, Nathan Pankratz, Dan E. Arking, Christina A. Castellani, Daniel Levy, John A. Lane, Myriam Fornage, James S. Floyd, Megan L. Grove, Jennifer A. Brody, Chunyu Liu, Jason A. Sumpter
BackgroundMitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-related diseases, including all-cause mortality. However, the mechanism by which mtDNA-CN influences disease is not currently understood. One such mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb54d5e275a77285c47a5ec735158812