Zobrazeno 1 - 10
of 16
pro vyhledávání: '"35"'
Autor:
Jonathan J. Knowlton, Gwen M. Taylor, Herbert W. Virgin, Danica M. Sutherland, Craig B. Wilen, Terence S. Dermody, Pavithra Aravamudhan, Kelly Urbanek, Robert C. Orchard
Engagement of cell-surface receptors by viruses is a critical determinant of viral tropism and disease. The reovirus attachment protein, σ1, binds sialylated glycans and proteinaceous receptors to mediate infection, but the specific requirements on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf05c1678d2df22adfd03907d4323b4
https://doi.org/10.1101/2020.08.03.235572
https://doi.org/10.1101/2020.08.03.235572
Autor:
Andrew Wang, Ala Trusina, Minjun Son, Savaş Tay, Sara Saheb Kashaf, Thomas Holst-Hansen, Tino Frank, Michael Junkin
Publikováno v:
Science Advances, 8 (35)
Son, M, Frank, T, Holst-Hansen, T, Wang, A G, Junkin, M, Kashaf, S S, Trusina, A & Tay, S 2022, ' Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs ', Science Advances, vol. 8, no. 35, 6240 . https://doi.org/10.1126/sciadv.abn6240
Son, M, Frank, T, Holst-Hansen, T, Wang, A G, Junkin, M, Kashaf, S S, Trusina, A & Tay, S 2022, ' Spatiotemporal NF-kappa B dynamics encodes the position, amplitude, and duration of local immune inputs ', Science Advances, vol. 8, no. 35, 6240 . https://doi.org/10.1126/sciadv.abn6240
Infected cells communicate through secreted signaling molecules like cytokines, which carry information about pathogens. How differences in cytokine secretion affect inflammatory signaling over space and how responding cells decode information from p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12cfd87b9731a2a6eed3396c5610c91
https://doi.org/10.1101/2021.11.30.470463
https://doi.org/10.1101/2021.11.30.470463
Positive and negative modes of regulation typically constrain synaptic growth and function within narrow physiological ranges. However, it is unclear how synaptic strength is maintained when both pre- and post-synaptic compartments continue to grow b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ddb1c03d5c68a5050f0900b38b11c1
https://doi.org/10.1101/840470
https://doi.org/10.1101/840470
Publikováno v:
Statistical Science
Statistical Science, Institute of Mathematical Statistics (IMS), 2020, 35 (1), pp.129-144. ⟨10.1214/19-STS7561⟩
Statist. Sci. 35, no. 1 (2020), 129-144
Statistical Science, Institute of Mathematical Statistics (IMS), 2020, 35 (1), pp.129-144. ⟨10.1214/19-STS7561⟩
Statist. Sci. 35, no. 1 (2020), 129-144
Recent years have produced a large amount of work on inference about cancer evolution from mutations identified in cancer samples. Much of the modeling work has been based on classical models of population genetics, generalized to accommodate time-va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1482c0df1efd095dd59f323fc8de536c
Autor:
Yoshiharu Nabekura, Tomoaki Kuji, Takehito Sugasawa, Keisuke Ishikura, Katsuyuki Tokinoya, Yasushi Kawakami, Seiji Maeda, Yasuko Yoshida, Nanami Sekine, Kumamoto S, Yasuhiro Shishikura, Keisei Kosaki, Yuichi Aita, Kazuhiro Takekoshi
PurposeCell-free DNA (cfDNA) has been investigated as a minimally invasive biomarker for many diseases, particularly cancer. An increase in cfDNA has been observed during exercise. Neutrophil extracellular traps (NETs) may be the origin of cfDNA in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bcf28c5a4100b7cc2493c7583a8f418
https://doi.org/10.1101/2021.03.06.434188
https://doi.org/10.1101/2021.03.06.434188
Autor:
Harold Mondragon Reyes, Mariana Aguilar Sánchez, Luis Enrique García Fernández, Jorge Angel Almeida Villegas, Iris Mellolzy Estrada Carrillo, Silvia Patricia Peña
IntroductionHigh levels of hyperglycemia lead to diabetes, the same levels that if not controlled increase the risk of diabetic neuropathy, which over time translates into loss of sensation and lesions that progress and lead to diabetic foot may occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::482a76cb34099b1c8e034f25773eec1d
https://doi.org/10.1101/2020.11.09.20228478
https://doi.org/10.1101/2020.11.09.20228478
Autor:
Trinh T. B. Tram, Do Dang Anh Thu, Guy E. Thwaites, Nguyen Hoan Phu, Hoang N. Nhung, Nguyen Thi Hanh, Vu T. N. Ha, Nguyen Thuy Thuong Thuong, Tran D. Dinh
Macrophages play a significant role in preventing infection through antimicrobial activities, particularly acidification and proteolysis. Mycobacterium tuberculosis infection can lead to diverse outcomes, from latent asymptomatic infection to active
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54848dda1d8532e71662a480fb3f6e52
https://doi.org/10.1101/2020.09.14.20194043
https://doi.org/10.1101/2020.09.14.20194043
Autor:
Inna V. Samsonova, Alexander Karaulov, Daria Fomina, Michael M. Lederman, Anton A. Chernov, Zinaida Yu. Mutovina, Irina P. Beloglazova, Nataliya G. Poteshkina, M. A. Lysenko, Tat'yana S. Kruglova
BackgroundEmerging evidence links morbidity and mortality of pandemic COVID-19 pneumonia to an inflammatory cytokine storm.MethodsEighty nine patients with COVID-19 pneumonia and heightened systemic inflammation (elevated serum C reactive protein and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6635535b2dc460646028a266c8c6471
Autor:
Jonàs Juan-Mateu, Ruichuan Yin, Farooq Syed, Yi Cui, Bobbie-Jo M. Webb-Robertson, Raghavendra G. Mirmira, Cailin Deiter, Jennifer E. Kyle, Julia Laskin, Lori Sussel, Ernesto S. Nakayasu, Carmella Evans-Molina, Kristin E. Burnum-Johnson, Michelle A. Guney, Charles Ansong, Decio L. Eizirik, Carrie D. Nicora, Thomas O. Metz, Galya Orr, Dylan Sarbaugh
SummaryLipids have been implicated as mediators of insulitis and β-cell death in type 1 diabetes development, but the mechanisms underlying this association are poorly understood. Here, we investigated the changes in islet/β-cell lipid composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91af1ef1f0a65646bd8696a124e92bc0
Autor:
Kaya, Berna, Cuadra, Cristian Doñas, Wuggenig, Philipp, Diaz, Oscar E., Morales, Rodrigo A., Melhem, Hassan, Hernández, Pedro P., Kaymak, Tanay, Das, Srustidhar, Hruz, Petr, Ayata, C. Korcan, Villablanca, Eduardo J., Niess, Jan Hendrik
SummarySingle nucleotide polymorphisms in the gene encoding G protein-coupled receptor 35 (GPR35) are associated with increased risk of inflammatory bowel disease. However, the mechanism(s) by which GPR35 modulates the intestinal milieu remain undefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc121780fd7fdfad7ac78881f7af484d
https://doi.org/10.1101/2020.02.03.932186
https://doi.org/10.1101/2020.02.03.932186