Zobrazeno 1 - 6
of 6
pro vyhledávání: '"35"'
Publikováno v:
Cell Reports, 35 (4)
Multi-subunit SMC ATPases control chromosome superstructure apparently by catalyzing a DNA-loop-extrusion reaction. SMC proteins harbor an ABC-type ATPase "head" and a "hinge" dimerization domain connected by a coiled coil "arm." Two arms in a SMC di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d016fad9f37a1df321b674e998b20142
https://doi.org/10.1101/2021.01.21.427566
https://doi.org/10.1101/2021.01.21.427566
Positive and negative modes of regulation typically constrain synaptic growth and function within narrow physiological ranges. However, it is unclear how synaptic strength is maintained when both pre- and post-synaptic compartments continue to grow b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ddb1c03d5c68a5050f0900b38b11c1
https://doi.org/10.1101/840470
https://doi.org/10.1101/840470
Autor:
Rob Phillips, Tal Einav
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Cellular behavior is ultimately governed by the genetic program encoded in the cell’s DNA and through the arsenal of molecular machines that actively transcribe its genes, yet we lack the ability to predict how an arbitrary DNA sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03374b8cc53adcfe0f185760673ff203
https://doi.org/10.1101/597989
https://doi.org/10.1101/597989
Autor:
Jonàs Juan-Mateu, Ruichuan Yin, Farooq Syed, Yi Cui, Bobbie-Jo M. Webb-Robertson, Raghavendra G. Mirmira, Cailin Deiter, Jennifer E. Kyle, Julia Laskin, Lori Sussel, Ernesto S. Nakayasu, Carmella Evans-Molina, Kristin E. Burnum-Johnson, Michelle A. Guney, Charles Ansong, Decio L. Eizirik, Carrie D. Nicora, Thomas O. Metz, Galya Orr, Dylan Sarbaugh
SummaryLipids have been implicated as mediators of insulitis and β-cell death in type 1 diabetes development, but the mechanisms underlying this association are poorly understood. Here, we investigated the changes in islet/β-cell lipid composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91af1ef1f0a65646bd8696a124e92bc0
Autor:
Kaya, Berna, Cuadra, Cristian Doñas, Wuggenig, Philipp, Diaz, Oscar E., Morales, Rodrigo A., Melhem, Hassan, Hernández, Pedro P., Kaymak, Tanay, Das, Srustidhar, Hruz, Petr, Ayata, C. Korcan, Villablanca, Eduardo J., Niess, Jan Hendrik
SummarySingle nucleotide polymorphisms in the gene encoding G protein-coupled receptor 35 (GPR35) are associated with increased risk of inflammatory bowel disease. However, the mechanism(s) by which GPR35 modulates the intestinal milieu remain undefi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc121780fd7fdfad7ac78881f7af484d
https://doi.org/10.1101/2020.02.03.932186
https://doi.org/10.1101/2020.02.03.932186
Autor:
Chris Bolden, S. Michael Owens, Michael D. Hambuchen, Paris Margaritis, Laura E. Ewing, William E. Fantegrossi, Shannon M. Zintner, Eric C. Peterson, Charles E. Hay, Juliana C. Small
Methamphetamine (METH) continues to be amongst the most addictive and abused drugs in the US. Unfortunately, there are currently no FDA approved pharmacological treatments for METH substance abuse disorder. As an alternative approach, we have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccbb65f823838cd30a8342555b0ba2b
https://doi.org/10.1101/687129
https://doi.org/10.1101/687129