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Autor:
Giuseppe A. Sautto, Sebastian Koppert, Carla Wolf, Greg A. Kirchenbaum, Ted M. Ross, Fridolin Franke, Paul V. Lehmann, Noemi Becza, Stefanie Kuerten
Publikováno v:
Cells; Volume 10; Issue 8; Pages: 1843
Cells
Cells, Vol 10, Iss 1843, p 1843 (2021)
Cells
Cells, Vol 10, Iss 1843, p 1843 (2021)
Assessment of humoral immunity to SARS-CoV-2 and other infectious agents is typically restricted to detecting antigen-specific antibody in the serum. Rarely does immune monitoring entail assessment of the memory B cell compartment itself, although it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b012def85fa4039af4795ce8579ecc6
https://doi.org/10.1101/2021.06.02.21258073
https://doi.org/10.1101/2021.06.02.21258073
Autor:
Yiliam Cruz, George V. Pérez, Katharina Zettl, Yassel Ramos, Ailyn C. Ramón, Mauro Rosales, Yasser Perera, Vladimir Besada, Luis Javier González, Evelin Caballero, Silvio E. Perea, Arielis Rodríguez-Ulloa, Daylen Aguilar, Ke Yang, Dania Marcia Vazquez-Blomquist, Jacek R. Wiśniewski
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 766, p 766 (2021)
Volume 9
Issue 7
Biomedicines, Vol 9, Iss 766, p 766 (2021)
Volume 9
Issue 7
Protein kinase CK2 has emerged as an attractive therapeutic target in acute myeloid leukemia (AML), advent that becomes particularly relevant since the treatment of this hematological neoplasia remains challenging. Here we explored for the first time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc20614c60f7bfa9e3e30996b7f8883
https://doi.org/10.1101/2021.05.19.444866
https://doi.org/10.1101/2021.05.19.444866
Junctophilin-2 (JPH2) was conventionally considered as a structural membrane binding protein. Recently, it was shown that proteolytically truncated mouse JPH2 variants are imported into nucleus to exert alternative functions. However, the intranuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d30292ed5afb446e037f7029d7d6cee
https://doi.org/10.1101/2021.05.17.444513
https://doi.org/10.1101/2021.05.17.444513
Solubility is a requirement for many cellular processes. Loss of solubility and aggregation can lead to the partial or complete abrogation of protein function. Thus, understanding the relationship between protein evolution and aggregation is an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed5c07f0b21ed9b02f6aea222d90ea7
https://doi.org/10.1101/2021.05.10.443436
https://doi.org/10.1101/2021.05.10.443436
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
For research on tendon injury, many different animal models are utilized; however, the extent to which these species simulate the clinical condition and disease pathophysiology has not yet been critically evaluated. Considering the importance of infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e56c20d61f0138d3f8943c46d6dcb5
https://doi.org/10.1101/2021.05.09.443263
https://doi.org/10.1101/2021.05.09.443263
A central processing event in eukaryotic gene expression is splicing. Concurrent with splicing, the core-EJC proteins, eIF4A3 and RBM8A-MAGOH heterodimer are deposited 24 bases upstream of newly formed exon-exon junctions. One of the core-EJC protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7095ecaa23aa5ec36fd747f38436df1
https://doi.org/10.1101/2021.05.07.443087
https://doi.org/10.1101/2021.05.07.443087
Autor:
Tandile Hermanus, Ki-Sung Kwon, rina song, Minsoo Kim, Prudence Kgagudi, Jong-In Kim, Carel A. van Baalen, Young-Il Kim, Cheol-Min Kim, Patricia M. Nuijten, Young Ki Choi, Penny L. Moore, Dong Kyun Ryu, Aloys Sl. Tijsma, Soo Young Lee, Thandeka Moyo-Gwete
Publikováno v:
Biochemical and Biophysical Research Communications
The global circulation of newly emerging variants of SARS-CoV-2 is a new threat to public health due to their increased transmissibility and immune evasion. Moreover, currently available vaccines and therapeutic antibodies were shown to be less effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760fdc72211cdd4621b8f53c21ea1de6
https://doi.org/10.1101/2021.04.27.441707
https://doi.org/10.1101/2021.04.27.441707
Autor:
Pia Fehrenbach, Özlem Sogukpinar, Dominik Bettinger, Sven A. Lang, Michael Schultheiss, Robert Thimme, A Schuch, B Zecher, Bertram Bengsch, Stefan Fichtner-Feigl, Maike Hofmann, Charlotte Rennert, Niklas K. Björkström, Peter Bronsert, Kathrin Heim, Catrin Tauber
Publikováno v:
Cells : open access journal 10(6), 1369 (2021). doi:10.3390/cells10061369 special issue: "Special Issue "T and NK Cell-Based Immunotherapy in Chronic Viral Hepatitis and Hepatocellular Carcinoma" / Special Issue Editors: Dr. Paola Fisicaro, Guest Editor; Dr. Carolina Boni, Guest Editor"
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1369, p 1369 (2021)
Cells
Volume 10
Issue 6
Cells, Vol 10, Iss 1369, p 1369 (2021)
Hepatocellular carcinoma (HCC) is a global health burden with increasing incidence, poor prognosis and limited therapeutic options. Natural killer (NK) cells exhibit potent anti-tumoral activity and therefore represent potential targets for immunothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b6cb0d4bb51970420bcd456ac16d4c
https://doi.org/10.1101/2021.04.16.440140
https://doi.org/10.1101/2021.04.16.440140
Autor:
Lee B. Smith, Diane Rebourcet, Isabelle Stévant, Emmanouil T. Dermitzakis, Annalucia Darbey, Yasmine Neirijnck, Françoise Kühne, Serge Nef, Pauline Sararols, Michael Curley
Leydig cells (LC) are the main testicular androgen-producing cells. In eutherian mammals, two types of LCs emerge successively during testicular development, fetal Leydig cells (FLCs) and adult Leydig cells (ALCs). Both display significant difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b76d4a99254a99f315f829ae5f1ac50
https://doi.org/10.1101/2021.04.14.439819
https://doi.org/10.1101/2021.04.14.439819
Elevated production of lactate is a key characteristic of aberrant tumour cell metabolism and can be non-invasively measured as an early marker of tumour response using deuterium (2H) magnetic resonance spectroscopy (MRS). Following treatment, change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b77fc199489c05ed6a146fcb2c78b152
https://doi.org/10.1101/2021.04.03.438324
https://doi.org/10.1101/2021.04.03.438324