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Publikováno v:
Neuron. (6):1435-1441
Baroreceptor nerve endings detect acute fluctuations in arterial pressure. We tested the hypothesis that members of the DEG/ENaC family of cation channels, which are responsible for touch sensation in Caenorhabditis elegans , may be components of the
Autor:
Jenny J. Yeh, Xiaojie Chen, Nicole Alessandri-Haber, Carlos Amílcar Parada, Jon D. Levine, Aileen E Boyd, David B. Reichling
Publikováno v:
Neuron. (3):497-511
We hypothesized that TRPV4, a member of the transient receptor family of ion channels, functions as a sensory transducer for osmotic stimulus-induced nociception. We found that, as expected for a transducer molecule, TRPV4 protein is transported in s
Publikováno v:
Neuron. (5):921-931
Dopamine neurons of the ventral tegmental area (VTA) are critically involved in processing novel and rewarding information, and mediate the addictive properties of many drugs of abuse. Excitatory synapses on these neurons, like those in other brain r
Autor:
Ruth Fabian-Fine, Arnaud Ruiz, Matthew C. Walker, Dimitri M. Kullmann, Ricardo Scott, Dmitri A. Rusakov
Publikováno v:
Neuron. (6):961-973
Presynaptic GABAA receptors modulate synaptic transmission in several areas of the CNS but are not known to have this action in the cerebral cortex. We report that GABAA receptor activation reduces hippocampal mossy fibers excitability but has the op
Publikováno v:
Neuron. (2):349-357
Nicotine reinforces smoking behavior by activating nicotinic acetylcholine receptors (nAChRs) in the midbrain dopaminergic (DA) reward centers, including the ventral tegmental area (VTA). Although nicotine induces prolonged excitation of the VTA in v
Autor:
Allan E. Herbison, R.J Bicknell, Karel S. Kits, Arjen B. Brussaard, August B. Smit, J.W Leyting-Vermeulen, P Voorn, W.P.A Willems, R.E. Baker
Publikováno v:
Scopus-Elsevier
We found that magnocellular oxytocin neurons in adult female rats exhibit an endogenous GABA(A) receptor subunit switch around parturition: a decrease in alpha1:alpha2 subunit mRNA ratio correlated with a decrease in allopregnanolone potentiation and
Autor:
Bhavya Trivedi, Richard H. Kramer
Publikováno v:
Neuron. (4):895-906
Cyclic GMP (cGMP) is a crucial intracellular messenger in neuronal, muscle, and endocrine cells. The intracellular concentration of cGMP is regulated by various neurotransmitters, including acetylcholine (ACh) and nitric oxide (NO). While much is kno
Autor:
Menahem Segal, Eduard Korkotian
Publikováno v:
Neuron. (3):751-758
Dendritic spines have long been known to contain contractile elements and have recently been shown to express apparent spontaneous motility. Using high-resolution imaging of dendritic spines of green-fluorescent protein (GFP)-expressing, patch-clampe