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Autor:
Katsuo Kamata, Hiroko Yamaura, Susumu Otomo, Shigeru Okuyama, Yutaka Kasuya, Katsuharu Tsuchida, Noriyuki Miyata
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 71:297-300
The endothelium-dependent relaxation of superior mesenteric arteries of Wistar and genetically diabetic WBN/Kob rats was compared. Endothelium-dependent relaxation induced by acetylcholine (ACh) and A23187 was depressed in WBN/Kob rats. Relaxation in
Autor:
Daniel Lamontagne, Jacques de Champlain, Christophe Ribuot, Réginald Nadeau, Nobuharu Yamaguchi
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1190-1195
The effect of ischemia on myocardial noradrenaline concentration and endogenous noradrenaline output was studied in the isolated perfused rat heart. Following a 15-min stabilization period, regional ischemia was produced by coronary artery ligation.
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1143-1148
Chronic diabetes enhances intestinal absorption of glucose and induces hyperphagia. We examined the enhanced intestinal absorption of glucose in ad libitum-fed rats with streptozocin-induced diabetes mellitus and compared these results with those obt
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:904-908
Prolongation of bradykinin half-life following kininase inhibition has been proposed as the reason for the potentiation of kinin effects. We have reassessed this assumption by using three different isolated smooth muscle preparations and simultaneous
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:746-751
The activity of lipoprotein lipase was measured in white and brown adipose tissues, red vastus lateralis muscle, and heart of rats that have been insulin deficient (streptozotocin, 75 mg∙kg−1) for 2 weeks, and that have then received implants of
Autor:
A. B. R. Thomson, Monika Keelan
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:592-598
This study was undertaken to examine the effect of supplementing chow for 2 weeks with 2% cheno- (CDC) or ursodeoxycholic (UDC) acid or cholestyramine (CHOL) on the intestinal morphology and in vitro uptake of bile acids in adult rats. Food intake wa
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 68:1520-1526
The acute effect of estradiol and progesterone on dopamine and serotonin metabolism in rat striatum was studied. One subcutaneous injection of 17β-estradiol (300 ng) and progesterone (150 μg) into intact male rats increased plasma levels of these s
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 68:1317-1321
Phosphofructokinase activity was measured in the sciatic nerve of streptozotocin-induced diabetic and nondiabetic rats. Average steady-state phosphofructokinase activity was obtained from three consecutive segments of the mid-femoral region in the le
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 68:1334-1337
Cerebral ischemia, induced in rats by occlusion of the middle cerebral artery resulted in infarcts affecting the basal ganglia and adjacent frontoparietal cortex. Resting oxygen consumption was similar for sham-operated and ischaemic rats immediately
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 68:657-662
Several recent reports have shown that the hepatic uptake and subsequent elimination of some substrates is faster in the presence of albumin than in its absence, as if some of the substrate bound to albumin was also available for uptake. In the prese