Zobrazeno 1 - 10
of 90
pro vyhledávání: ''
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 86:700-709
Sympathetic denervation is frequently observed in heart disease. To investigate the linkage of sympathetic denervation and cardiac arrhythmia, we developed a rat model of chemical sympathectomy by subcutaneous injections of 6-hydroxydopamine (6-OHDA)
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 84:823-833
Increased vasoconstrictor response to norepinephrine (NE) and endothelin (ET)-1 in arteries from diabetic animals is ameliorated by chronic endothelin receptor blockade with bosentan and was absent in endothelium-denuded arteries, suggesting the invo
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 83:413-422
Sex differences in the degree of high blood pressure have been described in several forms of experimental animal models of hypertension. However, the influence of sex on angiotensin II-induced hypertension has not been studied. In the present study,
Autor:
Bita Moazed, M Desautels
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 80:541-552
The objective of this study was to evaluate some of the mechanisms by which norepinephrine (NE) and insulin may influence protein degradation in mouse brown adipocytes differentiated in cultures. The effects of NE and insulin, alone or in combination
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 77:878-885
The aim of the present study was to investigate whether exogenous angiotensin I (AngI) is locally converted to angiotensin II (AngII), which in turn results in an increase in the adrenal catecholamine (CA) secretion in the adrenal gland in anesthetiz
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 77:367-374
The aim of the present study was to analyse modulations of adrenal catecholamine secretion from the adrenal gland of anesthetized dogs in response to locally administered angiotensin II (AngII) in the presence of either PD 123319 or CGP 42112, both o
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 74:1322-1326
Cholinergic agonists induce a rhythmical slow activity (RSA) in the in vitro rat hippocampus. RSA consists of bursts of activity separated by quiescent periods (interburst intervals). The activity involves activation of muscarinic receptors; however,
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:594-601
The mechanisms contributing to the contractile responses to two different concentrations of noradrenaline (NA) in rat aorta and mesenteric artery were compared using nifedipine, which inhibits calcium influx through dihydropyridine-sensitive channels
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 72:1544-1551
Maximum contractile responses of diabetic aortas incubated in the absence of extracellular Ca2+ to increasing Ca2+ (0.01–10 mM) in the presence of 1 μM noradrenaline, but not 40 mM KCl, were significantly increased compared with those of age-match
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 72:1148-1154
In vitro coronary artery responsiveness to noradrenaline, phenylephrine, and BHT-920 together with functional relaxation to acetylcholine was assessed in dogs at the early onset of pacing-induced heart failure (1 week) and in dogs recovered from hear