Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Theodore F, Logan"'
Autor:
Theodore F. Logan, Lee D. Cranmer, Jatinder Singh, Sanjiv S. Agarwala, Bret Taback, Theresa L. Luna, Christopher D. Lao, Marc S. Ernstoff, Sandra Aung, Lawrence E. Flaherty, Jose Lutzky, Brendan D. Curti, David H. Lawson, Joseph I. Clark
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Background Preclinical studies suggest that BRAF inhibitors enhance anti-tumor immunity and antigen presentation. Combination BRAF inhibition with immunotherapy is an appealing therapeutic approach. We sequenced vemurafenib with HD IL-2 in patients w
Autor:
Sumanta K. Pal, Robert A. Figlin, Lawrence Karsh, Mark A DeBenedette, Jeffrey M. Holzbeierlein, Jennifer J. Knox, Irina Y. Tcherepanova, Charles Nicolette, Viraj A. Master, Arkadiusz Z. Dudek, Asim Amin, W. Lee Williams, Douglas C Plessinger, Wilson H. Miller, Raymond S. Lance, Theodore F. Logan
Publikováno v:
Journal for Immunotherapy of Cancer
Background AGS-003 is an autologous immunotherapy prepared from fully matured and optimized monocyte-derived dendritic cells, which are co-electroporated with amplified tumor RNA plus synthetic CD40L RNA. AGS-003 was evaluated in combination with sun
Autor:
Jose Lutzky, Christopher D. Lao, Gerald Militello, Mohammed M. Milhem, David H. Lawson, Sanjiv S. Agarwala, James N. Lowder, Sandra Aung, Gregory A. Daniels, Brendan D. Curti, Joseph I. Clark, Bret Taback, Lee D. Cranmer, Venkatesh K. Rudrapatna, Marc S. Ernstoff, Henry B. Koon, Theodore F. Logan, Lawrence E. Flaherty
Publikováno v:
Journal for Immunotherapy of Cancer
Purpose: To investigate whether the Vemurafenib-induced increased tumor antigen expression, T lymphocyte infiltration and tumor debulking improve the complete response rate induced by HD IL-2 in metastatic melanoma and if there is synergistic toxicit