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Autor:
Andrew J. Aguirre, Ana C. Anderson, Matan Hofree, Jonathan H. Chen, Marios Giannakis, Genevieve M. Boland, Orit Rozenblatt-Rosen, Aviv Regev, Nir Hacohen, Karin Pelka
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundImmune responses to cancer are highly variable, with DNA mismatch repair-deficient (MMRd) tumors exhibiting more anti-tumor immunity than mismatch repair-proficient (MMRp) tumors. Almost all tumors are infiltrated with immune cells, but the