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Autor:
Catherine J. Harmer, Ilina Singh, Ly-Mee Yu, Judit Simon, Paul Harrison, Glyn Lewis, Chloe Edwards, Sophie Roberts, Phil J. Cowen, Jennifer M Rendell, Sheena K. Au-Yeung, James Griffiths, Fiona Chan, Stuart Watson, Rafal Bogacz, Michael Browning, Anthony J. Cleare, Jonathan Evans, Milensu Shanyinde, John R. Geddes, David Kessler, Andrea Cipriani, M J Attenburrow
Publikováno v:
Au-Yeung, S K, Griffiths, J, Roberts, S, Edwards, C, Yu, L-M, Bogacz, R, Rendell, J, Attenburrow, M-J, Watson, S, Chan, F, Cipriani, A, Cleare, A, Harmer, C J, Kessler, D, Evans, J, Lewis, G, Singh, I, Simon, J, Harrison, P J, Cowen, P, Shanyinde, M, Geddes, J & Browning, M 2021, ' PAX-D : study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression ', Evidence-Based Mental Health . https://doi.org/10.1136/ebmental-2021-300282
IntroductionClinical depression is usually treated in primary care with psychological therapies and antidepressant medication. However, when patients do not respond to at least two or more antidepressants within a depressive episode, they are conside
Publikováno v:
Emergency Medicine Journal. 38:829-841
A fit and well 30-year-old woman attended the Emergency department 24 hours after being bitten on the right index finger while feeding a squirrel in Hyde Park. On review, the bite was small and the wound looked clean. She was given a tetanus booster
Autor:
Aroub Lahham, Monique Corbett, Emma Handley, Bruna Wageck, Christie Mellerick, Amanda Nichols, Anne E Holland, Paolo Zanaboni, Ajay Mahal, Kathryn Barker, Pawel Czupryn, Christine F McDonald, Hayley Crute, Richard Wootton, Catherine J. Hill, Janet Bondarenko, Angela T Burge, Jennifer A. Alison, Paul O'Halloran, Narelle S Cox, Helen Boursinos, Heather MacDonald
Publikováno v:
Thorax. 77:643-651
RationalePulmonary rehabilitation is an effective treatment for people with chronic respiratory disease but is delivered to MethodsA multicentre randomised controlled trial with assessor blinding, powered for equivalence was undertaken. Individuals w
Autor:
John J. Leddy, Michael S. Freitas, Mohammad N Haider, Scott R. Darling, Adam Cunningham, Rajiv Jain, Heidi N Suffoletto, Barry Willer
Publikováno v:
British Journal of Sports Medicine. 55:1427-1434
ObjectiveThe Buffalo Concussion Physical Examination (BCPE) is a brief, but pertinent physical examination designed for the subacute, outpatient assessment of concussion. The purpose of this study was to perform the BCPE on a larger sample and derive
Autor:
Fairuz Boujibar, Francis-Edouard Gravier, Antoine Cuvelier, Jean-Marc Baste, Tristan Bonnevie, Guillaume Prieur, Pauline Smondack, Yann Combret, Jean-François Muir, Clément Medrinal
Publikováno v:
Thorax. 77:486-496
IntroductionExercise training before lung resection for non-small cell lung cancer is believed to decrease postoperative complications (POC) by improving cardiorespiratory fitness. However, this intervention lacks a strong evidence base.AimTo assess
Autor:
William Newman, Michael Papadakis, Jamie M. O’Driscoll, Konstantina Kipourou, Jonathan D. Wiles, S. Hulbert, Rajan Sharma, Gemma Parry-Williams, Jamie J. Edwards
Publikováno v:
British Journal of Sports Medicine. 55:1233-1238
ObjectiveA systematic review, meta-analysis and meta-regression were performed on selected studies to investigate the incidence of atrial fibrillation (AF) among athletes compared with non-athlete controls.DesignMeta-analysis with heterogeneity analy
Publikováno v:
Archives of Disease in Childhood. 107:259-264
BackgroundA recent systematic review and meta-analysis identified a paucity of randomised-controlled trials (RCTs) investigating the use of probiotics to reduce or prevent mucositis and infection in children with cancer.ObjectiveThis study evaluated
Publikováno v:
BMJ Supportive & Palliative Care. 13:117-120
ObjectivesSeveral reviews and meta-analyses have reported on music therapy for physical and emotional well-being among patients with cancer. However, the duration of music therapy offered may range from less than 1 hour to several hours. The aim of t
Publikováno v:
British Journal of Ophthalmology. 106:1514-1519
AimTo estimate the minimally important difference (MID) in change in National Eye Institute Visual Function Questionnaire-25 (VFQ-25) composite score using methods aligned with patient perception.MethodsRetrospective analysis of prospectively collect
Autor:
Alison Richards, Philippa Clery, Julian P T Higgins, Teona Serafimova, Caitlin L Ascough, Yasmin Moore, Parisa Sinai, Amberly Brigden, Hayley King, Esther Crawley, Nina Anderson
Publikováno v:
Archives of Disease in Childhood
Moore, Y, Serafimova, T, Anderson, N, King, H, Richards, A, Brigden, A L C, Sinai, P, Higgins, J P T, Ascough, C L, Clery, P & Crawley, E M 2021, ' Recovery from Chronic Fatigue Syndrome : a systematic review-heterogeneity of definition limits study comparison ', Archives of Disease in Childhood, vol. 106, no. 11, archdischild-2020-320196, pp. 1087-1094 . https://doi.org/10.1136/archdischild-2020-320196
Moore, Y, Serafimova, T, Anderson, N, King, H, Richards, A, Brigden, A L C, Sinai, P, Higgins, J P T, Ascough, C L, Clery, P & Crawley, E M 2021, ' Recovery from Chronic Fatigue Syndrome : a systematic review-heterogeneity of definition limits study comparison ', Archives of Disease in Childhood, vol. 106, no. 11, archdischild-2020-320196, pp. 1087-1094 . https://doi.org/10.1136/archdischild-2020-320196
Background Paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is a common illness with a major impact on quality of life. Recovery is poorly understood. Our aim was to describe definitions of recovery in paediatric CFS/ME, the