Zobrazeno 1 - 10
of 404
pro vyhledávání: ''
Autor:
Qing Liu, Emily M. Ko, Katherine Hicks-Courant, Colleen M. Brensinger, Marilyn M. Schapira, Genevieve P. Kanter
Publikováno v:
International Journal of Gynecologic Cancer. 32:695-703
12032 Background: The impact of primary oncologist specialty, medical oncology (MO) versus gynecologic oncology (GO), on intensity of care at the end of life (EOL) in elderly patients with gynecologic cancer is unclear. Methods: This retrospective co
Autor:
Andrea Ardizzoni, Sergio Azevedo, Belen Rubio-Viqueira, Delvys Rodriguez-Abreu, Jorge Alatorre-Alexander, Hans J M Smit, Jinming Yu, Konstantinos Syrigos, Elen Höglander, Monika Kaul, Jonathan Tolson, Youyou Hu, Hans Kristian Vollan, Thomas Newsom-Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005581
In patients with previously treated advanced or metastatic non-small cell lung cancer (NSCLC), atezolizumab therapy improves survival with manageable safety. The open-label, single-arm phase III/IV TAIL study (NCT03285763) evaluated atezolizumab mono
Autor:
Nobuyuki Yanagisawa, Tsutomu Yoshida, Tetuo Mikami, Kiyomi Hana, Yoshiki Murakumo, Makoto Saegusa, Masaaki Ichinoe, Isao Okayasu, Hideaki Ogata, Kazutoshi Shibuya, Norihiko Sengoku, Hitoshi Endou
Publikováno v:
Journal of Clinical Pathology
AimsL-type amino acid transporter 1 (LAT1) is a major Na+-independent neutral amino acid transporter, forming a complex with CD98hc. The aim of this study is to investigate the significance of LAT1 and CD98hc in invasive breast cancer.MethodsLAT1 and
Autor:
Franck Dequiedt, Maureen Cambier, Ingrid Struman, Edouard Louis, Olivier Nivelles, Julien Guiot, Fanny Gester, Monique Henket, Michel Malaise, Amandine Boeckx, Renaud Louis, Makon-Sébastien Njock
Publikováno v:
Thorax
IntroductionIdiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease of unknown aetiology and cure. Recent studies have reported a dysregulation of exosomal microRNAs (miRs) in the IPF context. However, the impact of I
Autor:
P. Osterlund, S. Kinos, P. Pfeiffer, T. Salminen, J.J.M. Kwakman, J.-E. Frödin, C.H. Shah, H. Sorbye, R. Ristamäki, P. Halonen, L.M. Soveri, E. Heervä, A. Ålgars, M. Bärlund, H. Hagman, R. McDermott, M. O’Reilly, R. Röckert, G. Liposits, R. Kallio, P. Flygare, A.J. Teske, E. van Werkhoven, C.J.A. Punt, B. Glimelius
Publikováno v:
ESMO open, 7(3):100427. Elsevier BV
ESMO Open
ESMO Open
Publisher Copyright: © 2022 The Author(s) Background: Capecitabine- or 5-fluorouracil (5-FU)-based chemotherapy is widely used in many solid tumours, but is associated with cardiotoxicity. S-1 is a fluoropyrimidine with low rates of cardiotoxicity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13f97b5f1a9aa6049448c1fbbc3f020
http://urn.fi/urn:nbn:fi-fe2023071190533
http://urn.fi/urn:nbn:fi-fe2023071190533
Autor:
Claire Faulkner, Kirsty Russell, Olivier Giger, Rogier ten Hoopen, Ruth T Casey, Newton A C S Wong
Publikováno v:
Journal of Clinical Pathology. 74:194-197
AimThere is no known specific biomarker or genetic signal for quadruple wild-type (qWT) gastrointestinal stromal tumours (GISTs). By next-generation sequencing (NGS) of different GIST subgroups, this study aimed to characterise such a biomarker espec
Autor:
Satoshi Tanaka, Takayuki Kiuchi, Masanobu Kitagawa, Naoko Yamaguchi, Akihiro Ishizu, Katsuji Marukawa, Takahiro Deguchi, Noriyuki Otsuka, Yoshihiro Matsuno, Masanori Kasahara, Utano Tomaru
Publikováno v:
Journal of Clinical Pathology. 74:84-90
AimCathepsins are proteases that regulate a wide range of physiological processes, including protein turnover, cell signalling and antigen presentation. Recent studies have shown that cathepsins are highly upregulated in many types of tumours. Of the
Autor:
Shubin Li, Biao Wang, Gang Liu, Qin Jin, Shu Zhang, Jingyu Ren, Chunyu Wang, Kan Ni, Yanfeng Dai
Publikováno v:
Journal of Clinical Pathology
AimsMethionyl–tRNA synthetase (MARS) is known to play a critical role in initiating translation and protection against cellular damages in vivo. The aim of this study was to clarify the role of MARS in breast cancer (BC) progression.MethodsThe expr
Autor:
Seema Kashyap, Sameer Bakhshi, Neelam Pushker, Lata Singh, Meher Rizvi, M.K. Singh, Seema Sen
Publikováno v:
British Journal of Ophthalmology. 105:48-56
BackgroundImmune checkpoint blockade strategies have gained attention in the treatment/prognosis of cancers by targeting the programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway alone or in combination with cytotoxic T-lymphocyte-assoc
Autor:
Yi Zhang, Wenjing Wang, Peng-Fei Ma, Yang Zhang, Rui Bi, Yunheng Sun, Ying Jing, Mei-Chun Cai, Wen Di, Shengzhe Zhang, Guanglei Zhuang, Li Tan, Xia Yin, Minhua Yu
Publikováno v:
Journal of Medical Genetics. 57:605-609
BackgroundOvarian clear cell carcinoma (OCCC) arises from endometriosis and represents a difficult-to-treat gynaecological malignancy, in part, because its spatial intratumour heterogeneity and temporal evolutionary trajectories have not been explici