Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xiawei Wei"'
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-30 (2024)
Abstract The Wnt/β-catenin signaling pathway plays a crucial role in various physiological processes, encompassing development, tissue homeostasis, and cell proliferation. Under normal physiological conditions, the Wnt/β-catenin signaling pathway i
Externí odkaz:
https://doaj.org/article/54cb6db11d10482199c9e07ec67ba941
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-38 (2024)
Abstract Inflammation has accompanied human beings since the emergence of wounds and infections. In the past decades, numerous efforts have been undertaken to explore the potential role of inflammation in cancer, from tumor development, invasion, and
Externí odkaz:
https://doaj.org/article/fd247cfe06424d9e9177627b15829729
Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-31 (2023)
Abstract Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their behavior is regulated through a complex interplay of networ
Externí odkaz:
https://doaj.org/article/4fa7598c537c4f0fa0bcf5bdc6da5f20
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-35 (2023)
Abstract Inflammasomes are macromolecular platforms formed in response to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns, whose formation would cause maturation of interleukin-1 (IL-1) family members and gasde
Externí odkaz:
https://doaj.org/article/894dae399c0342c19f08b50e2938ad2a
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-38 (2022)
Abstract Tumors are comprised of both cancer cells and surrounding stromal components. As an essential part of the tumor microenvironment, the tumor stroma is highly dynamic, heterogeneous and commonly tumor-type specific, and it mainly includes nonc
Externí odkaz:
https://doaj.org/article/d8abc3bdff3a4174a5ccac2ff5d1af4c
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-35 (2022)
Abstract Bruton’s tyrosine kinase (BTK) is an essential component of multiple signaling pathways that regulate B cell and myeloid cell proliferation, survival, and functions, making it a promising therapeutic target for various B cell malignancies
Externí odkaz:
https://doaj.org/article/9f3f7e5e4d0b46e99d1320a251a620d9
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-27 (2022)
Abstract Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic development and tissue regeneration. However, aberrant reactivation of EMT is associated with malignant properties of tumor cells during cancer progression
Externí odkaz:
https://doaj.org/article/29d28fc53c2142eab06a1e3ed228c043
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-20 (2022)
Abstract Transforming growth factor β (TGF-β) has long been identified with its intensive involvement in early embryonic development and organogenesis, immune supervision, tissue repair, and adult homeostasis. The role of TGF-β in fibrosis and can
Externí odkaz:
https://doaj.org/article/7aede832df5540a0a8dcb04ea2ea3743
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Cancer is a severe disease that substantially jeopardizes global health. Although considerable efforts have been made to discover effective anti-cancer therapeutics, the cancer incidence and mortality are still growing. The personalized anti
Externí odkaz:
https://doaj.org/article/e09972130b9d4806bab190196394c36c
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-26 (2022)
Abstract Research on tumor immunotherapy has made tremendous progress in the past decades, with numerous studies entering the clinical evaluation. The cancer vaccine is considered a promising therapeutic strategy in the immunotherapy of solid tumors.
Externí odkaz:
https://doaj.org/article/d452ed76ed064cbeb00241bef53f1fd3