Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Tito, P."'
Identification and characterization of a new potent inhibitor targeting CtBP1/BARS in melanoma cells
Autor:
Angela Filograna, Stefano De Tito, Matteo Lo Monte, Rosario Oliva, Francesca Bruzzese, Maria Serena Roca, Antonella Zannetti, Adelaide Greco, Daniela Spano, Inmaculada Ayala, Assunta Liberti, Luigi Petraccone, Nina Dathan, Giuliana Catara, Laura Schembri, Antonino Colanzi, Alfredo Budillon, Andrea Rosario Beccari, Pompea Del Vecchio, Alberto Luini, Daniela Corda, Carmen Valente
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-32 (2024)
Abstract Background The C-terminal-binding protein 1/brefeldin A ADP-ribosylation substrate (CtBP1/BARS) acts both as an oncogenic transcriptional co-repressor and as a fission inducing protein required for membrane trafficking and Golgi complex part
Externí odkaz:
https://doaj.org/article/1518a1c715734851bf4b6f4560bdaa4e
Autor:
Meletios Dimopoulos, Pieter Sonneveld, Salomon Manier, Annette Lam, Tito Roccia, Jordan M. Schecter, Patricia Cost, Lida Pacaud, Abbey Poirier, Gabriel Tremblay, Tommy Lan, Satish Valluri, Shaji Kumar
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Objectives The goal of the research was to assess the quantitative relationship between median progression-free survival (PFS) and median overall survival (OS) specifically among patients with relapsed/refractory multiple myeloma (RRMM) base
Externí odkaz:
https://doaj.org/article/0585a86fa1414c2e9c7c39d6be67cf00
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Combination therapies in cancer treatment have demonstrated synergistic or additive outcomes while also reducing the development of drug resistance compared to monotherapy. This study explores the potential of combining the chemot
Externí odkaz:
https://doaj.org/article/cd34df223e5c471f92b70251b87ef9b7
Autor:
Peter Makaula, Sekeleghe Amos Kayuni, Kondwani Chidzammbuyo Mamba, Grace Bongololo, Mathias Funsanani, Lazarus Tito Juziwelo, Janelisa Musaya, Peter Furu
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Mass drug administration is one of the key interventions recommended by WHO to control certain NTDs. With most support from donors, health workers distribute antihelminthic drugs annually in Malawi. Mean community coverage of MDA
Externí odkaz:
https://doaj.org/article/b78e96983d7a4197aa96482846878c80
Autor:
Naruhiko Ikoma, Travis Grotz, Hirofumi Kawakubo, Hyoung-Il Kim, Satoru Matsuda, Yuki Hirata, Atsushi Nakao, Loretta A. Williams, Xin Shelley Wang, Tito Mendoza, Xuemei Wang, Brian D. Badgwell, Paul F. Mansfield, Woo-Jin Hyung, Vivian E. Strong, Yuko Kitagawa
Publikováno v:
BMC Surgery, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background The current standard operation for proximal gastric and gastroesophageal junction (P/GEJ) cancers with limited esophageal extension is total gastrectomy (TG). TG is associated with impaired appetite and weight loss due to the loss
Externí odkaz:
https://doaj.org/article/6116cf959f86401d9ba5cb1e898af491
Autor:
Francesca Liccardo, Martyna Śniegocka, Claudia Tito, Alessia Iaiza, Tiziana Ottone, Mariadomenica Divona, Serena Travaglini, Maurizio Mattei, Rosella Cicconi, Selenia Miglietta, Giuseppe Familiari, Stefania Annarita Nottola, Vincenzo Petrozza, Luca Tamagnone, Maria Teresa Voso, Silvia Masciarelli, Francesco Fazi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Acute myeloid leukemia (AML) patients bearing the ITD mutation in the tyrosine kinase receptor FLT3 (FLT3-ITD) present a poor prognosis and a high risk of relapse. FLT3-ITD is retained in the endoplasmic reticulum (ER) and generat
Externí odkaz:
https://doaj.org/article/ce760a3147f546ac978dda45ec44dbda
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The clinical heterogeneity of chronic rhinosinusitis (CRS) and bronchial asthma is attributable to different underlying inflammatory profiles. However, the similarity between CRS with nasal polyps (CRSwNP) and type-2 asthma pathop
Externí odkaz:
https://doaj.org/article/454ef6ae896d418d925a91b1e807b76a
Autor:
Anna Corti, Loris De Cecco, Stefano Cavalieri, Deborah Lenoci, Federico Pistore, Giuseppina Calareso, Davide Mattavelli, Pim de Graaf, C. René Leemans, Ruud H. Brakenhoff, Marco Ravanelli, Tito Poli, Lisa Licitra, Valentina Corino, Luca Mainardi
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background . At present, the prognostic prediction in advanced oral cavity squamous cell carcinoma (OCSCC) is based on the tumor-node-metastasis (TNM) staging system, and the most used imaging modality in these patients is magnetic resonance
Externí odkaz:
https://doaj.org/article/70e9ed0a5e974d13933a26dc8dbdbbf4
Autor:
Amanda L. King, Alvina A. Acquaye-Mallory, Elizabeth Vera, Tito Mendoza, Jennifer Reyes, Macy L. Stockdill, Mark R. Gilbert, Terri S. Armstrong
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Primary brain tumor (PBT) patients experience higher levels of distress and anxiety than other solid tumor patients, particularly at the time of clinical evaluation when uncertainty about disease status is high (“scanxiety”).
Externí odkaz:
https://doaj.org/article/bbf381db329b4115b5ea6783adc0a7cb
Autor:
Francesca Tamarozzi, Tito Kibona, William A. de Glanville, Tauta Mappi, Elly Adonikamu, Anande Salewi, Kennedy Misso, Venance Maro, Adriano Casulli, Azzurra Santoro, Federica Santolamazza, Blandina T. Mmbaga, Sarah Cleaveland
Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-11 (2022)
Abstract Background There are close similarities between the life-cycles of Echinococcus granulosus sensu lato (E. granulosus s.l.) that causes cystic echinococcosis (CE) in humans and Taenia multiceps/Coenurus cerebralis that causes cerebral coenuro
Externí odkaz:
https://doaj.org/article/bb3aabd62deb41d69407ac3457cabc70