Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sven Perner"'
Autor:
Sandra Genduso, Vera Freytag, Daniela Schetler, Lennart Kirchner, Alina Schiecke, Hanna Maar, Daniel Wicklein, Florian Gebauer, Katharina Bröker, Christine Stürken, Karin Milde-Langosch, Leticia Oliveira-Ferrer, Franz L. Ricklefs, Florian Ewald, Gerrit Wolters-Eisfeld, Kristoffer Riecken, Ludmilla Unrau, Linda Krause, Hanibal Bohnenberger, Anne Offermann, Sven Perner, Susanne Sebens, Katrin Lamszus, Linda Diehl, Stefan Linder, Manfred Jücker, Udo Schumacher, Tobias Lange
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-24 (2023)
Abstract Background The immunological composition of the tumor microenvironment has a decisive influence on the biological course of cancer and is therefore of profound clinical relevance. In this study, we analyzed the cooperative effects of integri
Externí odkaz:
https://doaj.org/article/15a2e60098c04388b2f1c864ee3b2031
Autor:
Isabel Heidegger, Georgios Fotakis, Anne Offermann, Jermaine Goveia, Sophia Daum, Stefan Salcher, Asma Noureen, Hetty Timmer-Bosscha, Georg Schäfer, Annemiek Walenkamp, Sven Perner, Aleksandar Beatovic, Matthieu Moisse, Christina Plattner, Anne Krogsdam, Johannes Haybaeck, Sieghart Sopper, Stefanie Thaler, Markus A. Keller, Helmut Klocker, Zlatko Trajanoski, Dominik Wolf, Andreas Pircher
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-20 (2022)
Abstract Background Crosstalk between neoplastic and stromal cells fosters prostate cancer (PCa) progression and dissemination. Insight in cell-to-cell communication networks provides new therapeutic avenues to mold processes that contribute to PCa t
Externí odkaz:
https://doaj.org/article/3611b9c2fa1d4e1088f9050c913e7e3d
Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Autor:
Lina Merkens, Verena Sailer, Davor Lessel, Ella Janzen, Sarah Greimeier, Jutta Kirfel, Sven Perner, Klaus Pantel, Stefan Werner, Gunhild von Amsberg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Abstract Prostate cancer is a hormone-driven disease and its tumor cell growth highly relies on increased androgen receptor (AR) signaling. Therefore, targeted therapy directed against androgen synthesis or AR activation is broadly used and continual
Externí odkaz:
https://doaj.org/article/af616c4e41df4e3faad5f2ada80aa9e5
Autor:
Anna Cirkel, Klaus-Peter Wandinger, Claudia Ditz, Jan Leppert, Lars Hanker, Christoph Cirkel, Alexander Neumann, Jan Brocke, Romana Höftberger, Lars Komorowski, Sven Perner, Frank Leypoldt, Tobias Wagner-Altendorf, Thomas F. Münte, Georg Royl
Publikováno v:
Neurological Research and Practice, Vol 3, Iss 1, Pp 1-7 (2021)
Abstract Background Recently, antibodies against the alpha isoform of the glial-fibrillary-acidic-protein (GFAPα) were identified in a small series of patients with encephalomyelitis. Coexisting autoantibodies (NMDA receptor, GAD65 antibodies) have
Externí odkaz:
https://doaj.org/article/1c434f4d0b824aaaa5b6dcdc13d37f1a
Serum miR-122-5p and miR-206 expression: non-invasive prognostic biomarkers for renal cell carcinoma
Autor:
Frauke G. Heinemann, Yuri Tolkach, Mario Deng, Doris Schmidt, Sven Perner, Glen Kristiansen, Stefan C. Müller, Jörg Ellinger
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background MicroRNAs (miRNA) play a relevant role in carcinogenesis, cancer progression, invasion, and metastasis. Thus, they can serve as diagnostic/prognostic biomarkers. The knowledge on circulating miRNAs for clear cell renal cell carcin
Externí odkaz:
https://doaj.org/article/0e718b40ced4429c8761d3b7077c89eb
Autor:
Sebastian Marwitz, Lena Heinbockel, Swetlana Scheufele, Dörte Nitschkowski, Christian Kugler, Sven Perner, Martin Reck, Ole Ammerpohl, Torsten Goldmann
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-3 (2017)
Abstract Hwang et al. recently showed that VGF substantially contributes to the resistance of human lung cancer cells towards epidermal growth factor receptor kinase inhibitors. This was further linked to enhanced epithelial–mesenchymal transition.
Externí odkaz:
https://doaj.org/article/59c50c341cbb4950807df7f33f75089c
Autor:
Sebastian Marwitz, Swetlana Scheufele, Sven Perner, Martin Reck, Ole Ammerpohl, Torsten Goldmann
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-3 (2017)
Abstract Targeting checkpoint inhibitors using monoclonal antibodies results in significantly better outcome of cancer patients compared to conventional chemotherapy. However, the current companion diagnostics to predict response is so far suboptimal
Externí odkaz:
https://doaj.org/article/9f435a1c002f47cfb18fb21e6c3eec73
Autor:
Martin Reck, Sven Perner, Ole Ammerpohl, Torsten Goldmann, Swetlana Scheufele, Sebastian Marwitz
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-3 (2017)
Targeting checkpoint inhibitors using monoclonal antibodies results in significantly better outcome of cancer patients compared to conventional chemotherapy. However, the current companion diagnostics to predict response is so far suboptimal, since t
Autor:
Tanja Fehm, Sven Perner, Ralf Kurth, Hans Neubauer, Karen Petersen, Petra M. Bareiss, Annette Staebler, Friederike Müller, Lothar Kanz, Diethelm Wallwiener, Friederike Schneider, Falko Fend, Veit Scheble, Claudia Lengerke
Publikováno v:
BMC Cancer, Vol 11, Iss 1, p 42 (2011)
BMC Cancer
BMC Cancer
Background The SRY-related HMG-box family of transcription factors member SOX2 has been mainly studied in embryonic stem cells as well as early foregut and neural development. More recently, SOX2 was shown to participate in reprogramming of adult som