Zobrazeno 101 - 110
of 120
pro vyhledávání: '"Scarpa A"'
Autor:
Cinzia M. Bellettato, Maurizio Scarpa
Publikováno v:
Italian Journal of Pediatrics, Vol 44, Iss S2, Pp 127-133 (2018)
Abstract The mucopolysaccharidoses (MPS) are a heterogeneous group of in-born metabolic conditions caused by genetic defects that result in the absence or severe deficiency of one of the lysosomal hydrolases responsible for the degradation of glycosa
Externí odkaz:
https://doaj.org/article/f9b72374839742648e55c64cb8f35bbb
Autor:
Khader Shameer, M. Mercedes Perez-Rodriguez, Roy Bachar, Li Li, Amy Johnson, Kipp W. Johnson, Benjamin S. Glicksberg, Milo R. Smith, Ben Readhead, Joseph Scarpa, Jebakumar Jebakaran, Patricia Kovatch, Sabina Lim, Wayne Goodman, David L. Reich, Andrew Kasarskis, Nicholas P. Tatonetti, Joel T. Dudley
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 18, Iss S3, Pp 1-11 (2018)
Abstract Background Worldwide, over 14% of individuals hospitalized for psychiatric reasons have readmissions to hospitals within 30 days after discharge. Predicting patients at risk and leveraging accelerated interventions can reduce the rates of ea
Externí odkaz:
https://doaj.org/article/607b367228c842dc9e85593c26b8353a
Autor:
Matteo Fassan, Luca Vianello, Diana Sacchi, Giuseppe N. Fanelli, Giada Munari, Marco Scarpa, Rocco Cappellesso, Fotios Loupakis, Cristiano Lanza, Roberta Salmaso, Claudia Mescoli, Nicola Valeri, Marco Agostini, Edoardo D’Angelo, Sara Lonardi, Salvatore Pucciarelli, Nicola Veronese, Claudio Luchini, Massimo Rugge
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background No data is available on the molecular background of the extra-nodal extension (ENE) of lymph node metastasis (LN) in colorectal cancer (CRC). Methods A series of 22 ENE-positive CRCs was considered and three samples per case were
Externí odkaz:
https://doaj.org/article/a523dd3445434fc8bc5c63846818027a
Autor:
Cecily P. Vaughn, José Luis Costa, Harriet E. Feilotter, Rosella Petraroli, Varun Bagai, Anna Maria Rachiglio, Federica Zito Marino, Bastiaan Tops, Henriette M. Kurth, Kazuko Sakai, Andrea Mafficini, Roy R. L. Bastien, Anne Reiman, Delphine Le Corre, Alexander Boag, Susan Crocker, Michel Bihl, Astrid Hirschmann, Aldo Scarpa, José Carlos Machado, Hélène Blons, Orla Sheils, Kelli Bramlett, Marjolijn J. L. Ligtenberg, Ian A. Cree, Nicola Normanno, Kazuto Nishio, Pierre Laurent-Puig
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Gene fusion events resulting from chromosomal rearrangements play an important role in initiation of lung adenocarcinoma. The recent association of four oncogenic driver genes, ALK, ROS1, RET, and NTRK1, as lung tumor predictive b
Externí odkaz:
https://doaj.org/article/b32c4dd2b6ba4fa0b53d8d7901cbaab5
Autor:
Anais Del Curatolo, Fabiana Conciatori, Ursula Cesta Incani, Chiara Bazzichetto, Italia Falcone, Vincenzo Corbo, Sabrina D’Agosto, Adriana Eramo, Giovanni Sette, Isabella Sperduti, Teresa De Luca, Mirko Marabese, Senji Shirasawa, Ruggero De Maria, Aldo Scarpa, Massimo Broggini, Donatella Del Bufalo, Francesco Cognetti, Michele Milella, Ludovica Ciuffreda
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-14 (2018)
Abstract Background Mounting evidence suggests that RAF-mediated MEK activation plays a crucial role in paradox MAPK (re)activation, leading to resistance and therapeutic failure with agents hitting a single step along the MAPK cascade. Methods We ex
Externí odkaz:
https://doaj.org/article/6697bfb35edd4bf0a98c8c2fafd43c43
Autor:
C. Peraldo-Neia, P. Ostano, G. Cavalloni, Y. Pignochino, D. Sangiolo, L. De Cecco, E. Marchesi, D. Ribero, A. Scarpa, A. M. De Rose, A. Giuliani, F. Calise, C. Raggi, P. Invernizzi, M. Aglietta, G. Chiorino, F. Leone
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Effective target therapies for intrahepatic cholangiocarcinoma (ICC) have not been identified so far. One of the reasons may be the genetic evolution from primary (PR) to recurrent (REC) tumors. We aim to identify peculiar charact
Externí odkaz:
https://doaj.org/article/0776f4bebedf4626adae0dc69749dcf0
Autor:
Joseph Muenzer, Roberto Giugliani, Maurizio Scarpa, Anna Tylki-Szymańska, Virginie Jego, Michael Beck
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background Mucopolysaccharidosis type II (MPS II; Hunter syndrome) is a rare, X-linked disorder caused by deficient activity of the enzyme iduronate-2-sulfatase (I2S). Treatment is available in the form of enzyme replacement therapy (ERT) wi
Externí odkaz:
https://doaj.org/article/ae8b3e09268942928ca9f56510a11dfb
Autor:
Rossella Parini, Federica Deodato, Maja Di Rocco, Edoardo Lanino, Franco Locatelli, Chiara Messina, Attilio Rovelli, Maurizio Scarpa
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-9 (2017)
Abstract Mucopolysaccharidosis I-Hurler (MPS I-H) is the most severe form of a metabolic genetic disease caused by mutations of IDUA gene encoding the lysosomal α-L-iduronidase enzyme. MPS I-H is a rare, life-threatening disease, evolving in multisy
Externí odkaz:
https://doaj.org/article/cfa741142ece4f568cd344f804fa569f
Autor:
Francesco Cavallin, Rita Alfieri, Marco Scarpa, Matteo Cagol, Alberto Ruol, Matteo Fassan, Massimo Rugge, Ermanno Ancona, Carlo Castoro
Publikováno v:
BMC Surgery, Vol 17, Iss 1, Pp 1-7 (2017)
Abstract Background Nodal skip metastasis is a prognostic factor in some sites of malignancies, but its role in esophageal cancer is still unclear. The present study aimed to investigate occurrence and effect of nodal skip metastases in thoracic esop
Externí odkaz:
https://doaj.org/article/64246c775617430c82f64524eb328fda
Autor:
Joseph Muenzer, Simon A. Jones, Anna Tylki-Szymańska, Paul Harmatz, Nancy J. Mendelsohn, Nathalie Guffon, Roberto Giugliani, Barbara K. Burton, Maurizio Scarpa, Michael Beck, Yvonne Jangelind, Elizabeth Hernberg-Stahl, Maria Paabøl Larsen, Tom Pulles, David A. H. Whiteman
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-9 (2017)
Abstract Mucopolysaccharidosis type II (MPS II; Hunter syndrome; OMIM 309900) is a rare lysosomal storage disease with progressive multisystem manifestations caused by deficient activity of the enzyme iduronate-2-sulfatase. Disease-specific treatment
Externí odkaz:
https://doaj.org/article/644625605fdd4a72ba2e68722dbe780e