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Akademický článek
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Autor:
Das Undurti, George CLS, Jin H, Wohlford-Lename CL, O'Neill ME, Phipps JC, O'Shaughnessy P, Kline JN, Thorne PS, Schwartz DA
Publikováno v:
Respiratory Research, Vol 2, Pp 68528-L213 (2001)
Externí odkaz:
https://doaj.org/article/18e52844a27c4aedaac5b07840681210
Autor:
Lindsay James, Carone Dawn M, Brown Judy, Hall Laura, Qureshi Sohaib, Mitchell Sarah E, Jannetty Nicholas, Hannon Greg, Renfree Marilyn, Pask Andrew, O’Neill Michael, O’Neill Rachel
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 559 (2012)
Abstract Background Small RNAs have proven to be essential regulatory molecules encoded within eukaryotic genomes. These short RNAs participate in a diverse array of cellular processes including gene regulation, chromatin dynamics and genome defense.
Externí odkaz:
https://doaj.org/article/61000cec8c5c45f8b103f3e4fe6bdd74
Autor:
Ravenstijn Paulien GM, Drenth Henk-Jan, O'Neill Michael J, Danhof Meindert, de Lange Elizabeth CM
Publikováno v:
Fluids and Barriers of the CNS, Vol 9, Iss 1, p 4 (2012)
Abstract Background Changes in blood-brain barrier (BBB) functionality have been implicated in Parkinson's disease. This study aimed to investigate BBB transport of L-DOPA transport in conjunction with its intra-brain conversion, in both control and
Externí odkaz:
https://doaj.org/article/7673fb0658a343c59b541c05c9fb1b5c
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 334 (2009)
Abstract Background Large-scale genome rearrangements brought about by chromosome breaks underlie numerous inherited diseases, initiate or promote many cancers and are also associated with karyotype diversification during species evolution. Recent re
Externí odkaz:
https://doaj.org/article/995fac93dbbc42bba6d7b1473247d199
Autor:
O'Neill Michael C, Erill Ivan
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 57 (2009)
Abstract Background Searching for transcription factor binding sites in genome sequences is still an open problem in bioinformatics. Despite substantial progress, search methods based on information theory remain a standard in the field, even though
Externí odkaz:
https://doaj.org/article/c4cc50fc56fb4040878a48772b8d3d22
Autor:
Poyner David R, Brogna Saverio, Wen Jikai, Bora Nagamani, Grgic Ljuban, Darby Richard AJ, Bonander Nicklas, O'Neill Michael AA, Bill Roslyn M
Publikováno v:
Microbial Cell Factories, Vol 8, Iss 1, p 10 (2009)
Abstract Background The production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a truly rational manner. Typically eukaryotic protein production experiments have relied
Externí odkaz:
https://doaj.org/article/dc0f2a64401b487482c78cc7e89dc961
Autor:
Ali Clinton W, Ashfield Alison, Cassidy Andrew, McGregor Gillian, O'Neill Mary, Paulin Fiona EM, Munro Alastair J, Baker Lee, Purdie Colin A, Lane David P, Thompson Alastair M
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 281 (2008)
Abstract Introduction A functional polymorphism within MDM2, SNP309 T>G, has been linked to early onset cancer. This study examined clinical associations of breast cancer with SNP309 in a Scottish Caucasian population and investigated additional MDM2
Externí odkaz:
https://doaj.org/article/8d8a8d44aee54df7afb9320445166869
Autor:
Imumorin Ikhide, VandeBerg John L, Gondolphi Christina M, Ferreri Gianni C, Obergfell Craig J, Carone Benjamin R, Lawton Betty R, O'Neill Rachel J, O'Neill Michael J
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 205 (2008)
Abstract Background- Parent-specific methylation of specific CpG residues is critical to imprinting in eutherian mammals, but its importance to imprinting in marsupials and, thus, the evolutionary origins of the imprinting mechanism have been the sub
Externí odkaz:
https://doaj.org/article/8d54ea00eb444fe08e07a3066600db09
Autor:
Song Li, O'Neill Michael C
Publikováno v:
BMC Bioinformatics, Vol 4, Iss 1, p 13 (2003)
Abstract Background Microarray chips are being rapidly deployed as a major tool in genomic research. To date most of the analysis of the enormous amount of information provided on these chips has relied on clustering techniques and other standard sta
Externí odkaz:
https://doaj.org/article/9d06496a4c154cb2bc11cc02918cc6d6