Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael Snyder"'
Autor:
Jacob Schreiber, Carles Boix, Jin wook Lee, Hongyang Li, Yuanfang Guan, Chun-Chieh Chang, Jen-Chien Chang, Alex Hawkins-Hooker, Bernhard Schölkopf, Gabriele Schweikert, Mateo Rojas Carulla, Arif Canakoglu, Francesco Guzzo, Luca Nanni, Marco Masseroli, Mark James Carman, Pietro Pinoli, Chenyang Hong, Kevin Y. Yip, Jeffrey P. Spence, Sanjit Singh Batra, Yun S. Song, Shaun Mahony, Zheng Zhang, Wuwei Tan, Yang Shen, Yuanfei Sun, Minyi Shi, Jessika Adrian, Richard Sandstrom, Nina Farrell, Jessica Halow, Kristen Lee, Lixia Jiang, Xinqiong Yang, Charles Epstein, J. Seth Strattan, Bradley Bernstein, Michael Snyder, Manolis Kellis, William Stafford, Anshul Kundaje, ENCODE Imputation Challenge Participants
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-22 (2023)
Abstract A promising alternative to comprehensively performing genomics experiments is to, instead, perform a subset of experiments and use computational methods to impute the remainder. However, identifying the best imputation methods and what measu
Externí odkaz:
https://doaj.org/article/af322f5b401248609628ec2ad86cadd9
Autor:
Zoltán Maróti, Dóra Tombácz, István Prazsák, Norbert Moldován, Zsolt Csabai, Gábor Torma, Zsolt Balázs, Tibor Kalmár, Béla Dénes, Michael Snyder, Zsolt Boldogkői
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Objective In this study, we applied two long-read sequencing (LRS) approaches, including single-molecule real-time and nanopore-based sequencing methods to investigate the time-lapse transcriptome patterns of host gene expression as a respon
Externí odkaz:
https://doaj.org/article/fd43ba3a7f48434ca81e428c56f84935
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Alternative polyadenylation is commonly examined using cDNA sequencing, which is known to be affected by template-switching artifacts. However, the effects of such template-switching artifacts on alternative polyadenylation are ge
Externí odkaz:
https://doaj.org/article/56fe98e627614afcba8c13a4602188e1
Autor:
Jennifer B. Nuzzo, Diane Meyer, Michael Snyder, Sanjana J. Ravi, Ana Lapascu, Jon Souleles, Carolina I. Andrada, David Bishai
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The 2014–2016 Ebola outbreak was a wake-up call regarding the critical importance of resilient health systems. Fragile health systems can become overwhelmed during public health crises, further exacerbating the human, economic,
Externí odkaz:
https://doaj.org/article/84ae8a5ad9bc44dea91d1761dae0599d
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in high-throughput genotyping technology have markedly improved our understanding of g
Externí odkaz:
https://doaj.org/article/2f2168fcfb99424c9922301173538174
Autor:
Alexander F. Kern, Roy Moh Lik Ang, Hunter B. Fraser, Neil M. Khosla, Michael Snyder, Grace Xiaolu Yang
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Ecology and Evolution
BMC Ecology and Evolution
Background Natural selection can act on multiple genes in the same pathway, leading to polygenic adaptation. For example, adaptive changes were found to down-regulate six genes involved in ergosterol biosynthesis—an essential pathway targeted by ma
Autor:
Zsolt Balázs, István Prazsák, Gábor Torma, Zoltán Maróti, Dóra Tombácz, Tibor Kalmár, Norbert Moldován, Zsolt Boldogkői, Béla Dénes, Michael Snyder, Zsolt Csabai
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)
BMC Research Notes
BMC Research Notes
Objective In this study, we applied two long-read sequencing (LRS) approaches, including single-molecule real-time and nanopore-based sequencing methods to investigate the time-lapse transcriptome patterns of host gene expression as a response to Vac
Autor:
Sarah L Boddy, Ilaria Giovannelli, Eran Segal, Michael Snyder, Pamela J. Shaw, Matilde Sassani, Lynne Ann Barker, Johnathan Cooper-Knock, Christopher J McDermott, Eran Elinav
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
BMC Medicine
BMC Medicine
Background Much progress has been made in mapping genetic abnormalities linked to amyotrophic lateral sclerosis (ALS), but the majority of cases still present with no known underlying cause. Furthermore, even in families with a shared genetic abnorma
Autor:
Hugo Y. K. Lam, Sachdev S. Sidhu, Benjamin E. Turk, Raffi Tonikian, Janine Mok, Philip M. Kim, Mark Gerstein, Michael Snyder
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 243 (2010)
BMC Bioinformatics
BMC Bioinformatics
Background Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protein domains such as the SH3 binding domains and the kinase catalytic domai
Autor:
Joel Rozowsky, Christopher M. Yellman, Theodore Gibson, Philippe Lefrançois, Mark Gerstein, Raymond K. Auerbach, Michael Snyder, Ghia Euskirchen
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 37 (2009)
BMC Genomics
BMC Genomics
Background Short-read high-throughput DNA sequencing technologies provide new tools to answer biological questions. However, high cost and low throughput limit their widespread use, particularly in organisms with smaller genomes such as S. cerevisiae