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Autor:
Garvin Fiona, Barr Linda J, Vogel Janet L, Henderson Samuel T, Jones Julie J, Costantini Lauren C
Publikováno v:
Nutrition & Metabolism, Vol 6, Iss 1, p 31 (2009)
Abstract Background Alzheimer's disease (AD) is characterized by early and region-specific declines in cerebral glucose metabolism. Ketone bodies are produced by the body during glucose deprivation and are metabolized by the brain. An oral ketogenic
Externí odkaz:
https://doaj.org/article/7eb73e49647c4d52a1321baad1abce03
Autor:
Bishop Paul N, Boot-Handford Ray P, Huxley-Jones Julie, Park Hosil, Attwood Teresa K, Bella Jordi
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 599 (2008)
Abstract Background The small leucine-rich repeat proteins and proteoglycans (SLRPs) form an important family of regulatory molecules that participate in many essential functions. They typically control the correct assembly of collagen fibrils, regul
Externí odkaz:
https://doaj.org/article/5f611973ebd94c1ca5d1e80ea2b7293c
Autor:
Huxley-Jones Julie, Szöőr Balázs, McElhinney Helen, Tariq Humera, Brenchley Rachel, Stevens Robert, Matthews Keith, Tabernero Lydia
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 434 (2007)
Abstract Background The genomes of the three parasitic protozoa Trypanosoma cruzi, Trypanosoma brucei and Leishmania major are the main subject of this study. These parasites are responsible for devastating human diseases known as Chagas disease, Afr
Externí odkaz:
https://doaj.org/article/8b2c790afbac40679b67bb2208b2a499
Autor:
Toubaris George, Beck Christine, Clarke Toni-Kim, Huxley-Jones Julie, Robertson David L, Boot-Handford Raymond P
Publikováno v:
BMC Evolutionary Biology, Vol 7, Iss 1, p 63 (2007)
Abstract Background The metzincins are a large gene superfamily of proteases characterized by the presence of a zinc protease domain, and include the ADAM, ADAMTS, BMP1/TLL, meprin and MMP genes. Metzincins are involved in the proteolysis of a wide v
Externí odkaz:
https://doaj.org/article/702d1ec11a9e4dc19107b39f5057801f
Autor:
Boot-Handford Raymond P, Hurlstone Adam FL, Goonesinghe Alexander C, Huxley-Jones Julie, McLeish Jennifer A, Mould A Paul, Humphries Martin J
Publikováno v:
BMC Cell Biology, Vol 7, Iss 1, p 24 (2006)
Abstract Background Integrins comprise a large family of α,β heterodimeric, transmembrane cell adhesion receptors that mediate diverse essential biological functions. Higher vertebrates possess a single β1 gene, and the β1 subunit associates with
Externí odkaz:
https://doaj.org/article/2cfa4495794046678d45f9fbd3edb67b
Autor:
Robertson David L, Humphries Martin J, Mould A Paul, Ewan Richard, Huxley-Jones Julie, Boot-Handford Raymond P
Publikováno v:
BMC Evolutionary Biology, Vol 5, Iss 1, p 31 (2005)
Abstract Background Integrins are a functionally significant family of metazoan cell surface adhesion receptors. The receptors are dimers composed of an alpha and a beta chain. Vertebrate genomes encode an expanded set of integrin alpha and beta chai
Externí odkaz:
https://doaj.org/article/b6a8463b4a9a4fc08bd229031231c307