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Publikováno v:
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-13 (2021)
Pilot and Feasibility Studies
Pilot and Feasibility Studies
BackgroundStress can negatively impact an individual’s health and well-being and high levels of stress are noted to exist among college students today. While traditional treatment methods are plagued with stigma and transfer problems, newly develop
Autor:
Wei Hou, Bowen Xu, Guanghui Zhu, Xiaoxiao Zhang, Ying Zhang, Heping Wang, Zhe Wu, Jie Li, Ruike Gao
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-9 (2021)
Trials
Trials
Background Non-small-cell lung cancer (NSCLC) is usually diagnosed at an advanced stage, and chemotherapy is the main treatment for this disease. Kanglaite injections (KLTi) have been widely used for the treatment of cancer in China. KLTi combined wi
Autor:
Olivier Huet, Alexandra Jobert, Vincent Minville, Jean-Stéphane David, Delphine Flattres-Duchaussoy, Pierre Bouzat, Olivier Langeron, Fanny Feuillet, Marc Danguy des Déserts, Antoine Roquilly, Charlene Le Moal, Celine Lerebourg, Sigismond Lasocki, Nicolas Grillot, Elodie Faurel-Paul, Younes El Amine, Martine Tching-Sin, Nolwenn Chatel-Josse, Raphaël Cinotti, Mathieu Oudot, Karim Asehnoune, Matthias Garot, Nathalie Bruneau
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Trials
Trials, BioMed Central, 2021, 22 (1), ⟨10.1186/s13063-021-05192-x⟩
Trials
Trials, BioMed Central, 2021, 22 (1), ⟨10.1186/s13063-021-05192-x⟩
Background Rapid-onset paralytic agents are recommended to achieve muscle relaxation and facilitate tracheal intubation during rapid sequence induction in patients at risk of pulmonary aspiration of gastric contents. However, opioids are frequently u
Autor:
Ryan S Ottridge, Sarah Tearne, Matthew Nicholls, Christina Antza, Gemma Slinn, Asad Ali, Abd A. Tahrani, Smitaa Patel, Brendan G Cooper
Publikováno v:
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-11 (2021)
Pilot and Feasibility Studies
Pilot and Feasibility Studies
Background Obstructive sleep apnoea (OSA) is very common in patients with type 2 diabetes (T2D). We and others have shown that OSA was associated with diabetes-related microvascular complications in patients with T2D in cross-sectional and longitudin
Autor:
Christine Rieu, Fernando A. Bozza, Letizia Mancusi, Aurélien Mazeraud, Philippe Aegerter, Tarek Sharshar, Bruno Gonçalves, Shidasp Siami, Khaoussou Sylla
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Trials
Trials, BioMed Central, 2021, 22, pp.170. ⟨10.1186/s13063-021-05118-7⟩
Trials
Trials, BioMed Central, 2021, 22, pp.170. ⟨10.1186/s13063-021-05118-7⟩
Background As of mid-June 2020, 7,500,000 people were infected with SARS-CoV-2 worldwide and 420,000 people died, mainly from coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS). COVID-19-related ARDS is subject to
Autor:
Cornelia Jaekel, H. Nienhueser, G. Mechtesheimer, S. B. Harrabi, Jürgen Debus, M. Uhl, Adriane Hommertgen, Gerlinde Egerer, Burkhard Lehner, Katharina Seidensaal, Klaus Herfarth, Marc A. Schneider, Stefan Fröhling, Meinhard Kieser
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-9 (2021)
Trials
Trials
Background Following surgery for soft tissue sarcoma of the retroperitoneum, the predominant pattern of failure is local recurrence, which remains the main cause of death. Radiotherapy is utilized to reduce recurrence rates but the efficacy of this s
Autor:
Eli Mansour, Raisa G. Ulaf, Milena Monfort-Pires, Sergio Dertkigil, Tatiana Benaglia, Licio A. Velloso, Luciana C. Ribeiro, Maria Luiza Moretti, Jose Carlos de Lima-Junior, Bruna Bombassaro, Rafael Pimentel Maia, Eliana P. Araújo, Thyago A. Nunes, A. F. Bernardes, Flavia Fagundes Bueno, Thiago Martins Santos, Plínio Trabasso, Antonio Luis Eiras Falcão, Andre C. Palma, Rachel P Dertkigil
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Trials
Trials
Background SARS-CoV-2, the virus that causes COVID-19, enters the cells through a mechanism dependent on its binding to angiotensin-converting enzyme 2 (ACE2), a protein highly expressed in the lungs. The putative viral-induced inhibition of ACE2 cou
Autor:
Xue-Bin Li, Dan-Dan Yang, Zhao-Hui Zhang, Fang-Ting Yu, Xin Chen, Yu Wang, Li-Qiong Wang, Yun-Peng Tian, Cun-Cao Wu, Xian Wang, Jin-Ling Li, Jing Lu, Cun-Zhi Liu, Wei-Hua Guo, Jian-Feng Tu, Gang Yang, Fu-Yan Chen, Ying Lin, Jing-Wen Yang, Shi-Yan Yan, Guang-Xia Shi, Chao-Qun Yan, He-Wen Li, Zhu Rui, Chu-Xi Liang, Zhong Dai, Bang-Qi Wu, Ming-Long Chen, Hai-Ying Wang
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-9 (2021)
Trials
Trials
Background Atrial fibrillation (AF) is a common arrhythmia, which is closely related to cardiovascular morbidity and mortality. Although acupuncture is used in the treatment of AF, the evidence is insufficient. The objective of this pilot trial is to
Autor:
Michael J. Solomon, Jane M. Young, Nabila Ansari, Paula R. Beckenkamp, James Ratcliffe, Cherry E. Koh, Daniel Steffens, Phillip A. Munoz, Neil Pillinger, Freya Rubie
Publikováno v:
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-11 (2021)
Pilot and Feasibility Studies
Pilot and Feasibility Studies
Objective To establish the feasibility and acceptability of a preoperative exercise program, and to obtain pilot data on the likely difference in key surgical outcomes to inform the sample size calculation for a full-scale trial. Design Pilot randomi
Autor:
Elisabetta Magni, Maria Grazia Ercolino, Maria Rosaria Leo, Roberto Piperno, Roberta Bonora, Fabio La Porta, Emanuela Casanova, Valeria Petrone, Francesco Di Gregorio
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-11 (2021)
Trials
Trials
BackgroundLeft hemispatial neglect (LHN) is a neuropsychological syndrome often associated with right hemispheric stroke. Patients with LHN have difficulties in attending, responding, and consciously representing the right side of space. Various reha