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Autor:
Xiao-Yu Liu, Bing Kang, Yu-Xi Cheng, Chao Yuan, Wei Tao, Bin Zhang, Zheng-Qiang Wei, Dong Peng
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Purpose The purpose of the current study is to analyze the difference of short-term and oncologic outcomes between younger and older colorectal cancer (CRC) patients who underwent primary CRC surgery using a propensity score matching (PSM) analysis.
Autor:
Keyang Yang, Zhijing Wu, Hao Zhang, Nan Zhang, Wantao Wu, Zeyu Wang, Ziyu Dai, Xun Zhang, Liyang Zhang, Yun Peng, Weijie Ye, Wenjing Zeng, Zhixiong Liu, Quan Cheng
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-32 (2022)
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically, gliomas occur among all ages, more often seen in adults, which males are more susceptible than females. According to the fifth edition of the WHO Classificat
Aggressive variants of prostate cancer: underlying mechanisms of neuroendocrine transdifferentiation
Autor:
Lina Merkens, Verena Sailer, Davor Lessel, Ella Janzen, Sarah Greimeier, Jutta Kirfel, Sven Perner, Klaus Pantel, Stefan Werner, Gunhild von Amsberg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-20 (2022)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Prostate cancer is a hormone-driven disease and its tumor cell growth highly relies on increased androgen receptor (AR) signaling. Therefore, targeted therapy directed against androgen synthesis or AR activation is broadly used and continually improv
Autor:
Xiukuan Li, Fenghua Bai, Xingwei Wei, Tianbo Jin, Chen Li, Yutian Zhang, Mei Lin, Xiaoli Zhou, Yufei Xie, Chanyi He, Qi Lin, Ping He, Shuyuan Chu, Yipeng Ding
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Background Serum indicators AFP, CA50, CA125, CA153, CA19-9, CEA, f-PSA, SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide association study on 8 tumor markers of our 427 Han population in southern China, in order to ident
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Autor:
Helena Olbertova, Karla Plevova, Sarka Pavlova, Jitka Malcikova, Jana Kotaskova, Kamila Stranska, Michaela Spunarova, Martin Trbusek, Veronika Navrkalova, Barbara Dvorackova, Nikola Tom, Karol Pal, Marie Jarosova, Yvona Brychtova, Anna Panovska, Michael Doubek, Sarka Pospisilova
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
BMC Cancer
BMC Cancer
Background Telomeres are protective structures at chromosome ends which shorten gradually with increasing age. In chronic lymphocytic leukemia (CLL), short telomeres have been associated with unfavorable disease outcome, but the link between clonal e
Autor:
Cinzia Brunelli, Emanuela Zito, Sara Alfieri, Claudia Borreani, Anna Roli, Augusto Caraceni, Giovanni Apolone
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Background Despite evidence of the positive impact of routine assessment of patient-reported outcome measures (PROMs), their systematic collection is not widely implemented in cancer care. Aim To assess the knowledge, use and attitudes of healthcare
Autor:
Tomoko Yoshida, Kazuhiko Takeda, Toshihiko Kaneda, Hiroaki Yanagimoto, Takao Yoshida, Kayoko Kibata, Koji Tsuta, Takayasu Kurata, Hiroshige Yoshioka
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Background Immune checkpoint inhibitors prolong the survival of non-small cell lung cancer (NSCLC) patients. Although it has been acknowledged that there is some correlation between the efficacy of anti-programmed cell death-1 (PD-1) antibody therapy
Autor:
Yu-Zhong Yu, Dao-Jun Lv, Chong Wang, Xian-Lu Song, Tao Xie, Tao Wang, Zhi-Min Li, Jia-Ding Guo, Du-Jiang Fu, Kang-Jin Li, Ding-Lan Wu, Franky Leung Chan, Ning-Han Feng, Zhe-Sheng Chen, Shan-Chao Zhao
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-21 (2022)
Molecular Cancer
Molecular Cancer
Background More and more studies have shown that circular RNAs (circRNAs) play a critical regulatory role in many cancers. However, the potential molecular mechanism of circRNAs in prostate cancer (PCa) remains largely unknown. Methods Differentially
Autor:
Ran, Hailiang, Ma, Jie, Cai, Le, Zhou, Hai, Yuan, Zhongqin, Chen, Ying, Chang, Wei, Huang, Yunchao, Xiao, Yuanyuan
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
BMC Cancer
BMC Cancer
Background Serum cholinesterase (ChE) was found to be involved in cancer initiation and progression. However, the survival association between serum ChE and non-small cell lung cancer (NSCLC) has not been extensively discussed. In the present study,
Autor:
Astrid Louise Bjørn Bennedsen, Luyi Cai, Rune Petring Hasselager, Aysun Avci Özcan, Khadra Bashir Mohamed, Jens Ole Eriksen, Susanne Eiholm, Michael Bzorek, Anne-Marie Kanstrup Fiehn, Thomas Vauvert F. Hviid, Ismail Gögenur
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Bennedsen, A L B, Cai, L, Hasselager, R P, Özcan, A A, Mohamed, K B, Eriksen, J O, Eiholm, S, Bzorek, M, Fiehn, A-M K, Hviid, T V F & Gögenur, I 2022, ' An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer ', BMC Cancer, vol. 22, 62 . https://doi.org/10.1186/s12885-022-09169-0
BMC Cancer
Bennedsen, A L B, Cai, L, Hasselager, R P, Özcan, A A, Mohamed, K B, Eriksen, J O, Eiholm, S, Bzorek, M, Fiehn, A-M K, Hviid, T V F & Gögenur, I 2022, ' An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer ', BMC Cancer, vol. 22, 62 . https://doi.org/10.1186/s12885-022-09169-0
BMC Cancer
Background The immune system recognizes and destroys cancer cells. However, cancer cells develop mechanisms to avoid detection by expressing cell surface proteins. Specific tumour cell surface proteins (e.g. HLA-G, PD-L1, CDX2) either alone or in com