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Autor:
Joohyun Woo, Se Jeong Oh, Jeong-Yoon Song, Byung Joo Chae, Jung Eun Choi, Jeeyeon Lee, Heung Kyu Park, Korean Breast Cancer Society, Woosung Lim
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
Background In estrogen receptor (ER)-positive breast cancer (BC), young age is associated with poor prognosis. While very young patients respond better to chemotherapy, chemotherapy is less effective in ER-positive tumors than in ER-negative tumors.
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
Background Almost one-third of patients with diffuse large B-cell lymphoma (DLBCL) cannot be cured with initial therapy and will eventually succumb to the disease. Further elaboration of prognostic markers of DLBCL will provide therapeutic targets. I
Autor:
Bin Zhao, Yang Zhai, Lina Li, Jingjin Li, Linhan Chang, Zijun Liao, Yuzhen Wang, Qian Chen, Xu Li
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background Lung adenocarcinoma (LUAD) is the most common pathology subtype of lung cancer. In recent years, immunotherapy, targeted therapy and chemotherapeutics conferred a certain curative effects. However, the effect and prognosis of LUAD patients
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Cancer
BMC Cancer
Background The relationship between cancer and coagulation has been intensively studied in recent years; however, the effects of coagulation factors on oral squamous cell carcinoma (OSCC) have rarely been reported. This study aimed to investigate the
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer
BMC Cancer
Background Clear cell renal cell carcinoma is susceptible to ferroptosis, and immunotherapy is recently recommended as a priority for the initial treatment of metastatic clear cell renal carcinoma. Increased ferroptosis and immune activation can syne
Autor:
Ming Yao, Yimin Wang, Yu-An Dong, Cong Yan, Zhou Tong, Lulu Liu, Weijia Fang, Hangyu Zhang, Feifei Zhang, Weiqin Jiang, Yi Zheng, Peng Zhao
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-15 (2020)
BMC Medical Genomics
BMC Medical Genomics
Background Drug resistance is a major obstacle to effective cancer therapy. In order to detect the change in tumor genomic states under drug selection pressure, we use next-generation sequencing technology to investigate the underlying potential mech
Autor:
Lena Brückner, Mike Thomas, Marc A. Schneider, Inn Chung, Johannes Krisam, Farastuk Bozorgmehr, Stefan Rieken, Petros Christopoulos, Daniel Wilhelm Mueller
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
Background Non-small cell lung cancer is the most common cause of cancer death worldwide, highlighting the need for novel therapeutic concepts. In particular, there is still a lack of treatment strategies for the group of elderly and frail patients,
Autor:
Alana Cavadino, Mark J. McKeage, Prashannata Khwaounjoo, J. Mark Elwood, Phyu Sin Aye, Sandar Tin Tin
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
BMC Cancer
BMC Cancer
Background Targeted treatment with Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) is superior to systemic chemotherapy in non-small cell lung cancer (NSCLC) patients with EGFR gene mutations. Detection of EGFR mutations is
Autor:
Akinobu Taketomi, Shingo Shimada, Toshiya Kamiyama, Akihisa Nagatsu, Tatsuya Orimo, Hirofumi Kamachi, Yoh Asahi, Yuzuru Sakamoto
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-11 (2020)
World Journal of Surgical Oncology
World Journal of Surgical Oncology
Objectives The aim was to evaluate the prognostic factors, clinicopathological characteristics, and surgical outcomes after hepatectomy in very elderly patients with hepatocellular carcinoma (HCC). Methods We analyzed 796 patients with HCC from 2000
Autor:
Mona A. Kandil, Hagar A. Alagizy, Dalia Rifaat Al-Sharaky, Hala S. El-Rebey, Enas Megahed El-hosary, Hayam A Aiad, Mahmoud Abdel-Sattar Elshenawy
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-11 (2020)
Diagnostic Pathology
Diagnostic Pathology
Background Bladder cancer (BC) is one of the most common malignancies in Egypt, representing about 8.7% of cancers in both sexes with more predominance in males, making identification of valuable predictive and prognostic markers, mandatory. Cullin-R