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Autor:
Fengchao Lang, Nigel W. Fraser, Erlin Wang, Yafen Yu, Liping Yang, Lihong Li, Zhuoran Li, Guijun Chen, Xia Cao, Jumin Zhou, Xin Li
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-11 (2021)
Virology Journal
Virology Journal
Background Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus. Cohesin, a major constituent of interphase and mitotic chromosomes comprised of
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-12 (2020)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background We have previously reported 18S and 25S ribosomal RNA molecules in Candida albicans resistant to processive 5′ → 3′ exonuclease, appearing as cells approached stationary growth phase. Initial analysis pointed to extra phosphate(s) at
Autor:
Boyuan Li, yuan qing feng, yuan jun li, yong peng jiang, Cheng Li, Jie Huang, ke huan lun, hong yao, Xiong Ji, rong zhou, wen jia duan, hao nan zheng, Chenlu Wang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-28 (2020)
Genome Biology
Genome Biology
Background The relationship between transcription and the 3D chromatin structure is debated. Multiple studies have shown that transcription affects global Cohesin binding and 3D genome structures. However, several other studies have indicated that in
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-15 (2020)
Molecular Cancer
Molecular Cancer
seRNA is a noncoding RNA (ncRNA) transcribed from active super-enhancer (SE), through which SE exerts biological functions and participates in various physiological and pathological processes. seRNA recruits cofactor, RNA polymerase II and mediator t
Autor:
Mel Campbell, Yoshihiro Izumiya
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-10 (2020)
Journal of Biomedical Science
Journal of biomedical science, vol 27, iss 1
Journal of Biomedical Science
Journal of biomedical science, vol 27, iss 1
Kaposi’s sarcoma-associated herpesvirus (KSHV), also designated human herpesvirus 8 (HHV-8), has been linked to Kaposi’s sarcoma, as well as to primary effusion lymphoma (PEL), and a subset of multicentric Castleman’s disease. KSHV genomes are
Autor:
Alona Kuzmina, Simona Krasnopolsky, Lital Marom, Ran Taube, Rachel A. Victor, Koh Fujinaga, Jacob C. Schwartz
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-19 (2019)
Retrovirology
Retrovirology
Background The human immunodeficiency virus (HIV) cell reservoir is currently a main obstacle towards complete eradication of the virus. This infected pool is refractory to anti-viral therapy and harbors integrated proviruses that are transcriptional
Autor:
Ria X. Peschutter, Heike Siebert, Annalisa Marsico, Evgenia Ntini, Natasa Djurdjevac Conrad, Denise Anna Thiel
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-16 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background Although several studies have provided insights into the role of long non-coding RNAs (lncRNAs), the majority of them have unknown function. Recent evidence has shown the importance of both lncRNAs and chromatin interactions in transcripti
Autor:
Catherine DeMarino, Robert A. Barclay, James Erickson, Maria Cowen, Marc S. Weinberg, Mohammed Saifuddin, Chen Zeng, Thy T. Vo, Michelle L. Pleet, Tristan A. Scott, Dmytro Kovalskyy, Daniel O. Pinto, Fatah Kashanchi
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-17 (2019)
Retrovirology
Retrovirology
Background HIV-1 patients receiving combination antiretroviral therapy (cART) survive infection but require life-long adherence at high expense. In chronic cART-treated patients with undetectable viral titers, cell-associated viral RNA is still detec
Autor:
Huangxian Ju, Huajian Teng, Chao-Jun Li, Xiang Gao, Sheng Zhou, Jin Dai, Jinzhong Qin, Minghao Zheng, Qiting Ge, Qing Jiang, Jianxin Li, Yi Cao
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 14, Iss 1, Pp 1-10 (2019)
Journal of Orthopaedic Surgery and Research
Journal of Orthopaedic Surgery and Research
Background Proinflammatory cytokines, which can upregulate the expression of matrix-degrading enzymes in chondrocytes, play important roles in the development of osteoarthritis. BET family proteins, acting as the “readers” of acetylated modificat
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-18 (2018)
Background Human immunodeficiency virus type 1 (HIV-1) Tat protein plays an essential role in HIV-1 gene transcription. Tat transactivates HIV-1 long terminal repeat (LTR)-directed gene expression through direct interactions with the transactivation-