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Autor:
Andrey Sivkov, Svetlana Sivkova, Roman V. Gorenkov, Sergey Sivkov, Natalya P. Chernus, Tamara Savina
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia. Methods The study consists of 180 patients, aged 40–75 yea
Autor:
Jane Kabwe, Hirofumi Sawada, Masako Kawai, Kazuo Maruyama, Ayumu Yokochi, Yoshihide Mitani, Amphone Okada, Ayaka Omori, Toshikazu Ito, Junko Maruyama, Erquan Zhang
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiesterase-3 inh
Autor:
Shuyan Liu, Guoliang Zhang, Yingxia Liu, Juan Meng, Dongqi Wang, Jincheng Chen, Peng Yin, Muchun Zhu, Junxiao Gao, Gengwei Zhang, Ye Li, Qinglong Guo
Publikováno v:
Virology Journal, Vol 18, Iss 1, Pp 1-11 (2021)
Virology Journal
Virology Journal
Objectives The aim of this study was to evaluate the role of antiviral drugs in reducing the risk of developing severe illness in patients with moderate COVID-19 pneumonia. Methods This retrospective cohort study included 403 adult patients with mode
Autor:
Helena Erlandsson Harris, Karin Palmblad, Erik Sundberg, AnnaCarin Horne, Hanna Schierbeck, Ulf Andersson, Jan-Inge Henter
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Molecular Medicine
Molecular Medicine
Background Macrophage activation syndrome (MAS) is a potentially fatal complication of systemic inflammation. HMGB1 is a nuclear protein released extracellularly during proinflammatory lytic cell death or secreted by activated macrophages, NK cells,
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-8 (2021)
Parasites & Vectors
Parasites & Vectors
Background Dirofilaria immitis, a globally distributed filarial parasite of dogs, is known to cause serious or fatal cardiopulmonary disease. Client-owned dogs were enrolled in a clinical field study in the USA to evaluate the clinical effectiveness
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-7 (2020)
Parasites & Vectors
Parasites & Vectors
Background Infection with Angiostrongylus vasorum may cause severe clinical disease, even death in dogs, however, due to the often non-specific clinical signs, diagnosis is not always straightforward. Regular prophylactic treatment may offer a safe m
Autor:
Mirjan Thys, Leon Meyer, William R. Everett, Sean P. Mahabir, Kristina Kryda, Susan J. Holzmer, Csilla Becskei, David R. Young, Sara Chapin, Lori Carter
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-8 (2020)
Parasites & Vectors
Parasites & Vectors
Background Five studies were conducted to evaluate a novel oral combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™), for efficacy against induced flea infestations, speed of kill and effects on flea reproduction on do
Autor:
Kenji Tsuji, Jun Wada, Kenichi Inagaki, Kishio Toma, Kazuhiko Fukushima, Hitoshi Sugiyama, Takayuki Hara, Shinji Kitamura, Natsumi Matsuoka, Eiki Ichihara
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-5 (2020)
BMC Nephrology
BMC Nephrology
Background The advent of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with advanced malignancies. On the other hand, these drugs might cause immune-related adverse events (irAEs) including endocrinopathies
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-9 (2020)
Molecular Medicine
Molecular Medicine
Background D-allose was promising in the protection of ischemia/reperfusion (I/R) injury. We intended to investigate the function of D-allose in skin flap of rat followed by the injury of I/R and whether ERK signal pathway was involved in. Methods Th
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-5 (2019)
Journal of Medical Case Reports
Journal of Medical Case Reports
Background Overall, fungi are estimated to cause approximately 1% of prosthetic joint infections, Candida glabrata account for less than 10% of these cases. No well-defined treatment strategy is available. Case presentation A 71-year-old Caucasian ma