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Autor:
Ping-Chieh Pao, Li-Huei Tsai
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Cdk5 is a proline-directed serine/threonine protein kinase that governs a variety of cellular processes in neurons, the dysregulation of which compromises normal brain function. The mechanisms underlying the modulation of Cdk5, its modes of action, a
Autor:
Pablo Lopez-Bergami, María Belén Villanueva, María Victoria Castro, Jérémie Nsengimana, María Josefina Quezada, Edith Illescas, Luca Grumolato, Gastón Barbero, Julia Newton-Bishop
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
Background Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a Wnt5a receptor aberrantly expressed in cancer that was shown to either suppress or promote carcinogenesis in different tumor types. Our goal was to study the role of ROR2 in melan
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-28 (2021)
Journal of Biomedical Science
Journal of Biomedical Science
The discovery of various noncoding RNAs (ncRNAs) and their biological implications is a growing area in cell biology. Increasing evidence has revealed canonical and noncanonical functions of long and small ncRNAs, including microRNAs, long ncRNAs (ln
Autor:
Lili Feng, Yi Chang, Ying Chu, Shengjun Wang, Wei Lu, Fenghua Cao, Bo Shen, Ge Song, Zhihong Chen, Huaxi Xu, Jie Ma
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Myeloid-derived suppressor cells (MDSCs) are derived from bone marrow progenitor cells commonly, which is a heterogeneous cell group composed of immature granulocytes, dendritic cells, macrophages and early undifferentiated bone marrow precursor cell
Autor:
Magdalena Lebiedzinska-Arciszewska, Bartlomiej Pawlik, Piotr Rieske, Joanna Taha, Wojciech Fendler, Hanna Nieznanska, Miljan Kuljanin, Aneta Wlodarczyk, Dominika Michałek, Agnieszka Zmysłowska, Beata Małachowska, Joseph D. Mancias, Wojciech Młynarski, Marcin Stanczak, Maciej Borowiec, Mariusz R. Wieckowski, Dagmara Grot
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-14 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Wolfram syndrome (WFS) is a rare autosomal recessive syndrome in which diabetes mellitus and neurodegenerative disorders occur as a result of Wolframin deficiency and increased ER stress. In addition, WFS1 deficiency leads to calcium homeo
Autor:
Guo-Hao Huang, Liang Yi, Yan Xiang, Mao-jun Liao, Lin Yang, Wei Yang, Bao-Zhong Shi, Sheng-Qing Lv, Pengfei Wu
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-16 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Alzheimer’s disease (AD) and glioblastoma are the most common and devastating diseases in the neurology and neurosurgery departments, respectively. Our previous research reports that the AD-related protein Presenilin1 represses cell prol
Autor:
Yair Alfaro-Mora, Clementina Castro-Hernández, Rosa María Bermúdez-Cruz, Rodrigo E. Cáceres-Gutiérrez, Laura Tolentino-García, Luis A. Herrera, Guadalupe Domínguez-Gómez, José Díaz-Chávez
Publikováno v:
Cell Division, Vol 16, Iss 1, Pp 1-13 (2021)
Cell Division
Cell Division
Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the o
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology, 2021, 22 (1), pp.51. ⟨10.1186/s12860-021-00388-0⟩
BMC Molecular and Cell Biology, BioMed Central, 2021, 22 (1), ⟨10.1186/s12860-021-00388-0⟩
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology, 2021, 22 (1), pp.51. ⟨10.1186/s12860-021-00388-0⟩
BMC Molecular and Cell Biology, BioMed Central, 2021, 22 (1), ⟨10.1186/s12860-021-00388-0⟩
Background Apoptosis is a caspase regulated cell death present in all metazoans defined by a conserved set of morphological features. A well-described function of apoptosis is the removal of excessive cells during development and homeostasis. Recent
Autor:
Kolajo Adedamola Akinyede, Adewale Oluwaseun Fadaka, Ashwil Klein, Marshall Keyster, Musa Oyebowale Akanbi, Olalekan Olanrewaju Bakare
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
The seriousness and menace of the worldwide weight of ‘Alzheimer’s disease have been related to a few factors, which incorporate antioxidant system depletion, mutation of proteins, and high expression of cholinesterases due to aging, environmenta
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-13 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth factor (EGF) and its receptor, EGFR, are expressed in trophoblast cells.