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Autor:
Andrey Sivkov, Svetlana Sivkova, Roman V. Gorenkov, Sergey Sivkov, Natalya P. Chernus, Tamara Savina
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia. Methods The study consists of 180 patients, aged 40–75 yea
Autor:
Kerstin Wirkner, Thomas Ebert, Christoph Engel, Anke Tönjes, Mike Francke, Mengyu Wang, Tobias Elze, F. Rauscher, Michael Stumvoll, Joachim Thiery, Markus Loeffler, Peter Stenvinkel
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
BMC Medicine
BMC Medicine
Background Circumpapillary retinal nerve fiber layer thickness (cpRNFLT) as assessed by spectral domain optical coherence tomography (SD-OCT) is a new technique used for the detection and evaluation of glaucoma and other optic neuropathies. Before tr
Autor:
Cheng Zhang, Liu Lu, Yukai Xiang, Yulong Yang, Xiangyu Kong, Ruiqi Lu, Chuanqi He, Jingli Cai, Bosen Zhang
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background Pancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known to promote gallstone formation. This study aimed to investigate the bile biochemistry changes in gall
Autor:
Zujiang Yu, Guo-Qiang Zhang, Guang-Lin Cui, Guo-Fan Zhang, Qing-Lei Zeng, Jiang-Hai Xu, Guo-Tao Li, Guang-Ming Li, Fanpu Ji, Fu-Sheng Wang, Wan-Bao Lin
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Infectious Diseases
BMC Infectious Diseases
Background Liver injuries have been reported in patients with coronavirus disease 2019 (COVID-19). This study aimed to investigate the clinical role played by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods In this multicentre,
Autor:
Julien Ancel, Jeanne-Marie Perotin, Pierre Gaudry, Gaëtan Deslée, Richard Le Naour, Flora Lemaire, Frank Antonicelli, Sandra Dury, Sandra Audonnet, François Lebargy
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Respiratory Research
Respiratory Research, BioMed Central, 2021, 22 (1), ⟨10.1186/s12931-020-01609-4⟩
Respiratory Research
Respiratory Research, BioMed Central, 2021, 22 (1), ⟨10.1186/s12931-020-01609-4⟩
Background In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory cells secrete proteases and participate in elastin breakdown and genesis of elastin-derived peptides (EP). In the present study, we hypothesized that the patte
Autor:
Chenlu Zhang, Xiaojing Xu, Shengchao Wu, Wei Guo, Fei Huang, Yiyi Yu, Tianshu Liu, Mengling Liu, Li Liang, Minna Shen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
Background The aim of this study was to explore the utility of circulating free DNA (cfDNA) in the evaluation of clinical tumor burden and survival in Chinese patients with metastatic colorectal cancer (mCRC) and to preliminarily summarize some metas
Autor:
Andrzej Horban, Beata Wojtycha-Kwaśnica, Justyna D. Kowalska, Regina Beata Podlasin, Magdalena Thompson, Hanna Czeszko-Paprocka, Andrzej Pihowicz, Tomasz Dyda
Publikováno v:
European Journal of Medical Research, Vol 25, Iss 1, Pp 1-6 (2020)
European Journal of Medical Research
European Journal of Medical Research
Background COVID-19 is characterized by fast deterioration in the mechanism of cytokine storm. Therefore, treatment with immunomodulating agents should be initiated as soon as hyperinflammation is established. Evidence for the use of tocilizumab (TCZ
Autor:
Marcelo Amar, Michael Stagliano, Emma Staller, Nehal N. Mehta, Kianoush Jeiran, Alan T. Remaley, Martin P. Playford, Tomas Vaisar, Scott M. Gordon
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-10 (2020)
Lipids in Health and Disease
Lipids in Health and Disease
Background Niacin has modest but overall favorable effects on plasma lipids by increasing high density lipoprotein cholesterol (HDL-C) and lowering triglycerides. Clinical trials, however, evaluating niacin therapy for prevention of cardiovascular ou
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Respiratory Research
Respiratory Research
Background The importance of lipid mediators in allergic diseases has been long recognized, whereas little is known about their role in allergic bronchopulmonary aspergillosis (ABPA). We investigated whether lipid mediators are associated with ABPA.
Autor:
Xiangao Jiang, Hongying Yu, Xinchun Ye, Feng Sun, Lingyun Shao, Yang Li, Jing Wen Ai, Wenhong Zhang, Zhengxing Wu, Jichan Shi, Haocheng Zhang, Bin Xu, Xian Zhou, Qiran Zhang
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-6 (2020)
BMC Medicine
BMC Medicine
Background Coronavirus disease 2019 (COVID-19) has infected more than 4 million people within 4 months. There is an urgent need to properly identify high-risk cases that are more likely to deteriorate even if they present mild diseases on admission.