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Autor:
Andrey Sivkov, Svetlana Sivkova, Roman V. Gorenkov, Sergey Sivkov, Natalya P. Chernus, Tamara Savina
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia. Methods The study consists of 180 patients, aged 40–75 yea
Autor:
Xiaoyong Huang, Zhiqiang Wu, Wenbo Guo, Zhiyong Liu, Tengfei Li, Xu Bo, Weiguang Yu, Song Chen, Yanqing Wu, Pengfei Wang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background Not all patients with unresectable hepatocellular carcinoma (uHCC) benefit from treatment with immune checkpoint inhibitors and molecular-targeted agents. The aim of this retrospective study was to assess the efficacy and safety of pembrol
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Endocrine Disorders
BMC Endocrine Disorders
Aim The incidence rate of diabetes is increasing year by year, seriously threatening human health. As a predictor of glycemic control, glycated hemoglobin is reported to be related to various complications and prognoses of diabetes. Besides, HDL-C dy
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders
Background Epidemiological studies indicate increased prevalence of cardiovascular disease (CVD) among military personnel. Accordingly, identification of at-risk individuals and lifestyle modification such as improving diet quality can potentially in
Autor:
Nurul Choudhury, Ashley Jaggi, Rob van Maanen, Patrick J O Covernton, Margarita Landeira, Francis Fatoye, Mahmood Ali
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-18 (2021)
BMC Urology
BMC Urology
Background Combination drug therapy for lower urinary tract symptoms (LUTS) is beneficial to selected patients and recommended by guidelines. Patterns of real-world LUTS drug use, especially combination drug therapy, have not been studied extensively
Autor:
Jing Zhang, Jiangang Shi, Peng Cai, Yue Su, Ximing Xu, Yinlong Guo, Han Gao, Liang Shan, Yingjie Lu
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-15 (2021)
Molecular Medicine
Molecular Medicine
Background Neovasculogenesis is characteristic of herniated lumbar discs, in which extruded nucleus pulposus is prone to heme iron-induced cytotoxicity (increased oxidative stress causing ferroptosis). However, recent analyses of neovascularization a
Publikováno v:
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders
Background Homocysteine (Hcy) is considered to be a risk factor for cardiovascular and cerebrovascular diseases. Few studies have evaluated the distribution of Hcy on a large-scale health examination. Accordingly, this study aimed to investigate the
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer
BMC Cancer
Background Smoking increases DNA methylation and DNA damage, and DNA damage acts as a vital cause of tumor development. The DNA methyltransferase 3B (DNMT3B) enhances promoter activity and methylation of tumor suppressor genes. Tea polyphenols may in
Autor:
Cheng Zhang, Liu Lu, Yukai Xiang, Yulong Yang, Xiangyu Kong, Ruiqi Lu, Chuanqi He, Jingli Cai, Bosen Zhang
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background Pancreaticobiliary reflux (PBR) causes chronic inflammation of the gallbladder mucosa and changes in the bile components, which are known to promote gallstone formation. This study aimed to investigate the bile biochemistry changes in gall
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies
Background The results from clinical trials have revealed that the effects of resveratrol supplementation on bone mineral density (BMD) and bone biomarkers are inconsistent. Our objective was to determine the effects of resveratrol supplementation on