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Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-24 (2021)
Genome Biology
Genome Biology
BackgroundSpatial interactions and insulation of chromatin regions are associated with transcriptional regulation. Domains of frequent chromatin contacts are proposed as functional units, favoring and delimiting gene regulatory interactions. However,
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-4 (2021)
Genome Medicine
Genome Medicine
If each cancer cell produces on average more than one cancer cell, we see a net growth of the tumors and metastases and vice versa. We review recent clinical results for microsatellite stable metastatic colorectal cancer (MSS-mCRC) suggesting immunot
Autor:
Hao-Fei Wang, Bing-Zhou Xue, Xiaobing Jiang, Hongyang Zhao, Jian Xue, Dong-Ye Yi, Peng Fu, Han Tian, Qing Zhang, Wei Xiang, Ahmed Abdelmaksou, Minxuan Sun, Yujie Zhou, Nanxiang Xiong
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background The tumour microenvironment contributes to chemotherapy resistance in gliomas, and glioma-associated mesenchymal stromal/stem cells (gaMSCs) are important stromal cell components that play multiple roles in tumour progression. However, whe
Publikováno v:
BMC Family Practice, Vol 22, Iss 1, Pp 1-8 (2021)
BMC Family Practice
BMC Family Practice
Background Primary care physicians have diverse responsibilities. To collaborate with cancer specialists efficiently, they should prioritise roles desired by other collaborators rather than roles based on their own beliefs. No previous studies have r
Autor:
Minglun Li, Florian Kamp, Guillaume Landry, Michael Reiner, Vanessa Da Silva Mendes, Maximilian Niyazi, Christopher Kurz, Claus Belka, Stefanie Corradini, Lukas Nierer
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)
Radiation Oncology (London, England)
Radiation Oncology (London, England)
Background The aim of this study was to evaluate and compare the performance of intensity modulated radiation therapy (IMRT) plans, planned for low-field strength magnetic resonance (MR) guided linear accelerator (linac) delivery (labelled IMRT MRL p
Autor:
Lugyanti Sukrisman
Publikováno v:
Thrombosis Journal, Vol 19, Iss 1, Pp 1-5 (2021)
Thrombosis Journal
Thrombosis Journal
Background Myeloid cells express microparticles that could increase the expression of adhesion molecules including P-selectin. We aimed to evaluate the level of soluble P-selectin (sP-selectin) and prothrombin fragment 1 + 2 (F1 + 2), and to determin
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-5 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
The glutathione S-transferase P1(GSTP1) is an isoenzyme in the glutathione-S transferases (GSTs) enzyme system, which is the most abundant GSTs expressed in adult lungs. Recent research shows that GSTP1 is closely related to the regulation of cell ox
Autor:
Wuling Liu, Hemavathi Dhandapani, Xiangchun Shen, Krishnapriya M. Varier, Yaacov Ben-David, Jialei Song, Anling Hu, Babu Gajendran, Chunlin Wang, Yanmei Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Immunotherapeutic treatments are gaining attention due to their effective anti-tumor response. Particularly, the revolution of immune checkpoint inhibitors (ICIs) produces promising outcomes for various cancer types. However, the usage of immunothera
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-14 (2021)
Experimental Hematology & Oncology
Experimental Hematology & Oncology
Mantle cell lymphoma (MCL) is considered one of the most aggressive lymphoid tumors. However, it sometimes displays indolent behavior in patients and might not necessitate treatment at diagnosis; this has been described as “smoldering MCL” (SMCL)
Publikováno v:
Cellular & Molecular Biology Letters, Vol 26, Iss 1, Pp 1-12 (2021)
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters
Developmental endothelial locus-1 (Del-1) is a secretory, multifunctional domain protein. It can bind to integrins and phosphatidylserine. As a local tissue signal, it plays a regulatory role in the cancer microenvironment and inflammation. Del-1 has