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pro vyhledávání: ''
Autor:
C. Nelson Hayes, Eisuke Murakami, Wataru Okamoto, Kenichiro Kodama, Takashi Nakahara, Masami Yamauchi, Kazuaki Chayama, Daiki Miki, Tomokazu Kawaoka, Masataka Tsuge, Yuji Teraoka, Hiroshi Aikata, Michio Imamura, Yasutoshi Fujii, Shinsuke Uchikawa, Atsushi Ono, Hatsue Fujino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
BackgroundThere has been a recent surge in interest in predicting biological effects associated with genomic alterations in order to implement personalized cancer treatment strategies. However, no reports have yet evaluated the utility of profiling b
Autor:
Forough Saki, Sanaz Dastghaib, Farhad Koohpeyma, Shaghayegh Allahyari, Marzieh Mahmoodi, Morvarid Siri
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-11 (2021)
BMC Nephrology
BMC Nephrology
BackgroundMonosodium glutamate (MSG) is frequently consumed as a flavor enhancer or food additive. Possible damages induced by MSG effects on some organs have been stated in experimental animal models. The aim of the present study was to evaluate the
Autor:
Zhiqiang Meng, Yawen Geng, Chao Qu, Lina Yang, Fengjiao Wang, Zhen Chen, Dan Wang, Shulin Yu, Chien-Shan Cheng, Lianyu Chen, Lai Wang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
Background Kaempferol, a natural flavonoid, exhibits anticancer properties by scavenging reactive oxygen species (ROS). However, increasing evidence has demonstrated that, under certain conditions, kaempferol can inhibit tumor growth by upregulating
Autor:
Maneerat Chayanupatkul, Duangporn Werawatganon, Kanjana Somanawat, Prasong Siriviriyakul, Naruemon Klaikeaw, Tanittha Chatsuwan, Nisarat Phetnoo
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Gastroenterology
BMC Gastroenterology
BackgroundHelicobacter pylori(H. pylori) infection is a major cause of chronic gastritis, peptic ulcer diseases and cancer. Genistein (4′,5,7-trihydroxyisoflavone), a tyrosine-specific-protein kinase inhibitor, has been shown to exert an anti-infla
Autor:
Fei Yan, Cheng ying Zhu, Li ping Dou, Hao Wang, Baoxu Pang, Yong hui Li, Meng zhen Wang, Xiao kai Wang, Dai hong Liu, Yu chen Liu, Chun ji Gao, Shujun Liu, Xiao su Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-19 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Induction therapy for acute myeloid leukemia (AML) is an anthracycline-based chemotherapy regimen. However, many patients experience a relapse or exhibit refractory disease (R/R). There is an urgent need for more effective regimens to reve
Autor:
Dongqing Guo, Weili Li, Xiaoqian Sun, Qian Zhang, Yanyan Jiang, Chun Li, Yong Wang, Qiyan Wang, Xiaoping Wang, Wenji Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Doxorubicin is effective in a variety of solid and hematological malignancies. Unfortunately, clinical application of doxorubicin is limited due to a cumulative dose-dependent cardiotoxicity. Dihydrotanshinone I (DHT) is a natural product
Autor:
Jing He, Mei Hong, Shiwang Li, Shao-tao Tang, Yuanyuan Chu, Jiarui Pu, Harish C. Joshi, Duo Li, Qiangsong Tong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Runt-related transcription factor 1 (RUNX1) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters and can accelerate apoptosis in various tumors. However, the regulatory mechanisms underlyin
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine
BackgroundAstragaloside IV (AS-IV) was reported to play a role in improving diabetic nephropathy (DN), however, the underlying mechanisms still remain unclear. The aim of the present study is to investigate whether AS-IV ameliorates DN via the regula
Autor:
Qi Zhou, Junbin Liao, Jianting Long, Sui Peng, Lixia Xu, Zhenwei Peng, Huilin Jin, Yu Guo, Shaoqiang Li, Guangyan Wei, Ming Kuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Limited effective intervention for advanced hepatocellular carcinoma (HCC) is available. This study aimed to investigate the potential clinical utility of apatinib, a highly selective inhibitor of the vascular endothelial growth factor rec
Autor:
Bo Ram Choi, Hye Kyung Kim, Ji Hoon Kim, Jae Hyung You, Chul Young Kim, Keshab Kumar Karna, Sung Won Lee, Wan Shou Cui, Yu Seob Shin, Jong Kwan Park
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine
Background Monotropein, astragalin, and spiraeoside (MAS) are active compounds extracted from medicinal herbs; monotropein from Morinda officinalis How (Rubiaceae), astragalin (kaempferol 3-O-glucoside) from Cuscuta chinensis Lamark (Convolvulaceae)