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Publikováno v:
REPRODUCTION. 143:523-529
Sertoli cell proliferation occurs in two major waves after birth, one neonatally and another prepubertally, each contributing to final testicular size and sperm production. However, little is known about the regulation of either wave. We have previou
Publikováno v:
Reproduction. 134:493-501
Passage of spermatozoa through the epididymis and emission of sperm during ejaculation are based on spontaneous and induced contractions of epididymal peritubular muscle layers. This study deals with the ejaculation-relevant factors noradrenaline (NA
Autor:
Anna Wagner, R Claus
Publikováno v:
Reproduction. 127:275-283
Active GnRH immunization of boars inhibits LH and testicular steroids but the consequences for spermatogenesis are unknown. Six boars were immunized three times against GnRH at 20, 24 and 28 weeks. Another six boars served as controls. Plasma LH and
Publikováno v:
Reproduction. :93-99
The administration of prolactin to hypophysectomized rats results in regression of the corpora lutea, accompanied by immune-inflammatory events such as infiltration of monocytes and macrophages. Recent reports indicate an autocrine role for progester
Autor:
S M Feng, G W Almond
Publikováno v:
Reproduction. 113:83-89
The present study examined the effects of LH, prostaglandin E2 (PGE2), 8-bromo-cyclic AMP (cAMP) and forskolin on progesterone secretion by small and large pig luteal cells. Corpora lutea were isolated from gilts (n > or = 3 per day) on days 9, 12 an
Publikováno v:
Journal of Endocrinology. 156:461-467
The rate-limiting step of steroidogenesis is the transport of the substrate cholesterol from the outer to the inner mitochondrial membrane which involves a cycloheximide-sensitive newly synthesized protein. A protein believed to carry out this functi
Autor:
Sandra J. Downing, M. Hollingsworth
Publikováno v:
Reproduction. 99:121-129
The influence of oestradiol benzoate and progesterone treatment and of tolerance to relaxin on the uptake of 125I-labelled porcine relaxin by reproductive tissues was investigated in anaesthetized female rats. In ovary-intact rats, 125I-labelled rela
Publikováno v:
Reproduction. 98:153-158
The role of relaxin and oestrogen in the remodelling of connective tissue was investigated by testing collagenase-dispersed cells (3 x 10(5) cells per well) from the uterine cervix of gilts for relaxin binding and collagen secretion. Relaxin-binding
Autor:
M. Hollingsworth, Sandra J. Downing
Publikováno v:
Journal of Endocrinology. 135:17-28
The influence of oestradiol benzoate and progesterone on uterine sensitivity and development of tolerance to relaxin was investigated in bilaterally ovariectomized non-pregnant rats in vivo. Bolus doses of relaxin (2–20 μg/kg i.v.) produced rapid
Publikováno v:
Reproduction. 89:69-76
Adult male rhesus monkeys were injected intramuscularly 100 micrograms, 1000 micrograms 5 alpha-androstane-3 alpha, 17 beta-diol or 100 micrograms dihydrotestosterone (DHT) per day for 70 days. A decrease in seminiferous tubular diameter was seen in