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Publikováno v:
Endocrine Connections, Vol 9, Iss 11, Pp R241-R250 (2020)
Endocrine Connections
Endocrine Connections
The current standard of care for hypothyroidism is levothyroxine (LT4) monotherapy to reduce levels of thyrotropin (thyroid-stimulating hormone, TSH) within its reference range and amelioration of any symptoms. A substantial minority continues to rep
Autor:
Ernesto Solá-Sánchez, Hector R Cintron-Colon, Michelle Mangual-Garcia, Nicolás Cruz-Dardíz, Shayanne Lajud, Marina Torres-Torres, Nadyeschka Rivera-Santana, Alex González-Bossolo
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2020)
Endocrinology, Diabetes & Metabolism Case Reports
Endocrinology, Diabetes & Metabolism Case Reports
Summary Lingual thyroid (LT) gland is the most common type of ectopic thyroid tissue, but it is an extremely rare presentation. We present a case of a 41-year-old Hispanic female patient complaining of dysphonia and dysphagia. As part of the evaluati
Autor:
Laia Casamitjana Espuña, Ismael Capel, Assumpta Caixàs, Jose León Mengíbar, Mercedes Rigla, Isabel Mazarico, Teresa Bonfill
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2019)
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2019)
Summary Durvalumab, a human immunoglobulin G1 kappa monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 and CD80 (B7.1) molecules, is increasingly used in advanced neoplasias. Durvalumab use is asso
Autor:
Martina Sabatini, Giorgio Iervasi, Daria Colligiani, Alessandro Saba, Riccardo Donzelli, Monica Nannipieri, Alice Accorroni, Leonardo Lorenzini, Riccardo Zucchi, Claudia Kusmic
Publikováno v:
European Thyroid Journal. 5:27-34
Background and Objective: The present study was aimed at determining the effects of experimental hypothyroidism and hyperthyroidism on tissue thyroid hormones by a mass spectrometry-based technique. Methods: Rats were subjected to propylthiouracil tr
Publikováno v:
Journal of Endocrinology. 185:111-119
Thyroid disease has profound effects on cardiovascular function. Hypo- and hyperthyroidism, for example, are associated with reduced and increased maximal endothelium-dependent vasodilation respectively. We therefore hypothesized that the capacity fo
Publikováno v:
Journal of Endocrinology. 135:495-505
The effects of various durations of postnatal hypothyroidism followed by recovery were studied on testicular growth in Long–Evans and Sprague–Dawley rats from birth to 7 months. Hypothyroidism was induced by adding propylthiouracil (PTU) in drink
Publikováno v:
Journal of Endocrinology. 131:67-73
The effects of thyroid state on liver mitochondrial protein mass was investigated in rats at 24 and 4 °C, as was oxidative phosphorylation using substrates which represent the final catabolic products of the metabolic fuels. In rats at 24 °C, a sig
Publikováno v:
Journal of Molecular Endocrinology. 5:1-6
Thyroid and steroid hormones act by similar mechanisms to influence gene expression in the anterior pituitary gland. The genes encoding the common α and TSH-β glycoprotein subunits are known to be regulated by thyroid hormones; we report here the e
Publikováno v:
Journal of Endocrinology. 71:143-155
SUMMARY Glycerol release from adipose tissue of adult genetically obese (ob/ob) mice was greater than that from adipose tissue of lean litter-mates. However, a higher concentration of adrenaline was required to stimulate lipolysis in ob/ob adipose ti
Autor:
Jerome M. Hershman, A. E. Pekary, Ronald S. Swerdloff, Masahiro Sugawara, V. Smith, Shalender Bhasin
Publikováno v:
Journal of Endocrinology. 114:271-277
Thyrotrophin-releasing hormone (TRH) occurs in high concentrations in the rat ventral prostate and its concentration is regulated in a positive dose–response manner by testosterone in castrated rats. α-Amidation of the tetrapeptide precursor, TRH-