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Autor:
Stephen Callahan, Mark Kidd, Daniele Alaimo, Irvin M. Modlin, Ignat Drozdov, Lisa Bodei, Nancy Teixiera
Publikováno v:
Endocrine-Related Cancer. 21:615-628
A critical requirement in neuroendocrine tumor (NET) management is a sensitive, specific and reproducible blood biomarker test. We evaluated a PCR-based 51 transcript signature (NETest) and compared it to chromogranin A (CgA), pancreastatin (PST) and
Autor:
Marianne Pavel, Katharina Detjen, Henning Jann, Tabea Neumann, Georg Hilfenhaus, Andreas Göhrig, Ulrich-Frank Pape, Dietmar Zdunek, Jean Marie Stassen, Georg Hess, Christian Fischer, Bertram Wiedenmann
Publikováno v:
Endocrine-Related Cancer. 20:305-319
Placental growth factor (PlGF), a VEGF-homolog implicated in tumor angiogenesis and adaptation to antiangiogenic therapy, is emerging as candidate target in malignancies. Here, we addressed the expression, function, and prognostic value of PlGF in ne
Autor:
Mykola Hulchiy, Anders Höög, Andrii Dinets, Jan Zedenius, Anastasios Sofiadis, Catharina Larsson, Mehran Ghaderi
Publikováno v:
European Journal of Endocrinology
BackgroundIncreased incidence of papillary thyroid carcinoma (PTC) is observed as a consequence of radiation exposure in connection to the Chornobyl nuclear plant accident in 1986. In this study, we report a cohort of adult Ukrainian patients diagnos
Autor:
Diana E. Benn, Adele Clarkson, Bruce G. Robinson, Anthony J. Gill, Kerrie L. McDonald, Patsy S. Soon, Stan B. Sidhu
Publikováno v:
Endocrine-Related Cancer. 16:573-583
The management of adrenocortical tumors (ACTs) is complex. The Weiss score is the present most widely used system for ACT diagnosis. An ACT is scored from 0 to 9, with a higher score correlating with increased malignancy. However, ACTs with a score o
Autor:
Emilio Bajetta, I. La Torre, A. Martinetti, Ettore Seregni, Emilio Bombardieri, M. Del Vecchio, D Paleari, Leonardo Ferrari, R. Longarini, L Toffolatti, Nicoletta Zilembo
Publikováno v:
Endocrine-Related Cancer. 11:771-779
Osteoprotegerin (OPG) is a potent antiresorptive molecule that binds NF-kappaB ligand, the final effector for osteoclastogenesis. OPG production is regulated by a number of cytokines and hormones. Osteopontin (OPN) is a secreted adhesive glycoprotein