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Autor:
Kreepa G Kooblall, Victoria J Stokes, Omair A Shariq, Katherine A English, Mark Stevenson, John Broxholme, Benjamin Wright, Helen E Lockstone, David Buck, Simona Grozinsky-Glasberg, Christopher J Yates, Rajesh V Thakker, Kate E Lines
Publikováno v:
Endocrine-Related Cancer. 29:557-568
Multiple endocrine neoplasia type 1 (MEN1), caused by mutations in the MEN1 gene encoding menin, is an autosomal dominant disorder characterised by the combined occurrence of parathyroid, pituitary and pancreatic neuroendocrine tumours (NETs). Develo
Autor:
Kalpana Gopalakrishnan, Susan L. Teitelbaum, Marilie D. Gammon, Humberto Parada, Regina M. Santella, Jia Chen, Vasily N. Aushev
Publikováno v:
Endocrine-Related Cancer. 26:843-851
Environmental phenols and phthalates are common ingredients in personal care products and some have been implicated in breast cancer progression. We have previously identified genes differentially expressed in response to low-dose exposure to diethyl
Autor:
Nicolle Besselink, Pier Selenica, Pjotr Prins, Britta Weigelt, Bert van der Vegt, Cathy B. Moelans, Peter Bult, Carmen C. van der Pol, Marco J. Koudijs, Marlous Hoogstraat, Robert Kornegoor, Jorge S. Reis-Filho, Paul J. van Diest, Natalie D. ter Hoeve, Isaac J. Nijman, Elsken van der Wall, Edwin Cuppen, Emile E. Voest, John W.M. Martens, Petra van der Groep, Wendy W.J. de Leng, Joep de Ligt, Miangela M. Lacle, Ellis Barbé, Vincent T.H.B.M. Smit
Publikováno v:
Endocr Relat Cancer
Endocrine-Related Cancer, 26(10), 779-794. Society for Endocrinology
Endocrine-Related Cancer, 26(10), 779. Society for Endocrinology
Endocrine-Related Cancer, 26(10), 779-794. Bioscientifica Ltd
Endocrine-Related cancer, 26(10), 779-794. BIOSCIENTIFICA LTD
Moelans, C B, de Ligt, J, van der Groep, P, Prins, P, Besselink, N J M, Hoogstraat, M, ter Hoeve, N D, Lacle, M M, Kornegoor, R, van der Pol, C C, de Leng, W W J, Barbé, E, van der Vegt, B, Martens, J, Bult, P, Smit, V T H B M, Koudijs, M J, Nijman, I J, Voest, E E, Selenica, P, Weigelt, B, Reis-Filho, J S, van der Wall, E, Cuppen, E & van Diest, P J 2019, ' The molecular genetic make-up of male breast cancer ', Endocrine-Related Cancer, vol. 26, no. 10, pp. 779-794 . https://doi.org/10.1530/ERC-19-0278
Endocrine-Related Cancer, 26(10), 779-794. Society for Endocrinology
Endocrine-Related Cancer, 26(10), 779. Society for Endocrinology
Endocrine-Related Cancer, 26(10), 779-794. Bioscientifica Ltd
Endocrine-Related cancer, 26(10), 779-794. BIOSCIENTIFICA LTD
Moelans, C B, de Ligt, J, van der Groep, P, Prins, P, Besselink, N J M, Hoogstraat, M, ter Hoeve, N D, Lacle, M M, Kornegoor, R, van der Pol, C C, de Leng, W W J, Barbé, E, van der Vegt, B, Martens, J, Bult, P, Smit, V T H B M, Koudijs, M J, Nijman, I J, Voest, E E, Selenica, P, Weigelt, B, Reis-Filho, J S, van der Wall, E, Cuppen, E & van Diest, P J 2019, ' The molecular genetic make-up of male breast cancer ', Endocrine-Related Cancer, vol. 26, no. 10, pp. 779-794 . https://doi.org/10.1530/ERC-19-0278
Male breast cancer (MBC) is extremely rare and accounts for less than 1% of all breast malignancies. Therefore, clinical management of MBC is currently guided by research on the disease in females. In this study, DNA obtained from 45 formalin-fixed p
Autor:
Donna C. Ferguson, Vivian L. Weiss, Kim Ely, Kensey N. Bergdorf, Thomas Stricker, Mitra Mehrad
Publikováno v:
Endocr Relat Cancer
The prevalence of thyroid carcinoma is increasing and represents the most common endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent subtype. The genetic alterations identified in PTCs fail to distinguish tumors with
Autor:
Brendan M. Finnerty, Rasa Zarnegar, Irene M. Min, Yi-Chieh Nancy Du, Olivier Elemento, Zhengming Chen, Akanksha Verma, Marco Seandel, Anna Aronova, Dean P. Edwards, Theresa Scognamiglio, Maureen D. Moore, Shixia Huang, Thomas J. Fahey
Publikováno v:
Endocrine-Related Cancer. 26:411-423
Loss of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) expression by CpG promoter hypermethylation is associated with metastasis in gastroenteropancreatic neuroendocrine tumors; however, the mechanism of how UCHL1 loss contributes to metastatic pot
Autor:
C. Benedikt Westphalen, Annelore Altendorf-Hofmann, Katharina Brüwer, Jens Werner, Thomas Kirchner, Stefan Boeck, Volker Heinemann, Florian Bösch, Gabriele Schubert-Fritschle, Christoph J. Auernhammer, Martin K. Angele, Christine Spitzweg, Thomas Knösel
Publikováno v:
Endocrine-Related Cancer. 26:293-301
Cancer immunotherapy has evolved major breakthroughs in the last years. The cell-surface receptor programmed death-1 (PD-1) and its ligand, programmed death ligand-1 (PD-L1), have been detected in various cancer types. However, the analysis on gastro
Autor:
Chihwan Cha, Chang Ik Yoon, Sung Gwe Ahn, Soeun Park, Yoon Jin Cha, Soong June Bae, Hye Sun Lee, Joon Jeong, Jae Hoon Lee, Kyung A. Lee
Publikováno v:
Endocrine-Related Cancer
On the basis of TP53 mutations and standardized uptake values (SUVs) from 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET), we sought to enhance our knowledge of the biology underlying low progesterone receptor (PR) expression in est
Publikováno v:
Endocr Relat Cancer
Immune checkpoint inhibitors have shown promising results in different cancers, and correlation between immune infiltration, expression of programmed death-ligand 1 (PD-L1) by tumor cells and response to immunotherapy has been reported. There is limi
Autor:
Karolina Windloch, Frank Gannon, Donal J. Brennan, Jason Sang Hun Lee, Greg Kelly, Eva Baxter
Publikováno v:
Endocrine-Related Cancer. 26:31-46
Up to 80% of endometrial and breast cancers express oestrogen receptor alpha (ERα). Unlike breast cancer, anti-oestrogen therapy has had limited success in endometrial cancer, raising the possibility that oestrogen has different effects in both canc
Autor:
Matthew P. Humphries, Tom Lees, Valerie Speirs, Angharad Cullinane, Abeer M Shabaan, Alexandra Condon
Publikováno v:
Endocrine-Related Cancer. 25:773-781
Male breast cancer (MBC) incidence seems to parallel global increases in obesity. The stromal microenvironment contributes to carcinogenesis; yet, the role of adipocytes in this is understudied in MBC. We identified four cohorts of male breast tissue