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Autor:
Donna C. Ferguson, Vivian L. Weiss, Kim Ely, Kensey N. Bergdorf, Thomas Stricker, Mitra Mehrad
Publikováno v:
Endocr Relat Cancer
The prevalence of thyroid carcinoma is increasing and represents the most common endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most frequent subtype. The genetic alterations identified in PTCs fail to distinguish tumors with
Autor:
Levent Dizdar, Sina C. Schütte, Wolfram T. Knoefel, Pablo E. Verde, Inga Nolten, Thomas A. Werner, Jasmin C. Riemer, Matthias Schott, Andreas Krieg, Katharina Raba
Publikováno v:
Endocrine-Related Cancer. 25:295-308
Follicular thyroid cancer’s (FTC) excellent long-term prognosis is mainly dependent on postoperative radioactive iodine (RAI) treatment. However, once the tumour becomes refractory, the 10-year disease-specific survival rate drops below 10%. The ai
Autor:
Jung Han Kim, Sun Wook Kim, Jae Hoon Chung, Soo Yeon Hahn, Tae Hyuk Kim, Hye Won Jang, Jung Hee Shin, Young Lyun Oh, Chang-Seok Ki, Jun-Ho Choe, Soomin Ahn, Jee Soo Kim
Publikováno v:
Endocrine-Related Cancer. 24:97-106
PD-L1 expression is being considered a potential biomarker for response of anti-PD-1 or anti-PD-L1 agents in various tumors. The reported frequency of PD-L1 positivity varies in thyroid carcinomas, and multiple factors may contribute to the variabili
Autor:
Joanne Ngeow, Danielle Gurin, Shireen Ganapathi, Benjamin Fletcher, Richard T. Kloos, Ying Ni, Charis Eng, Rebecca Nagy, Spencer Seballos, Thomas LaFramboise, Matthew D. Ringel
Publikováno v:
Endocrine-Related Cancer
Along with breast and endometrial cancers, thyroid cancer is a major component cancer in Cowden syndrome (CS). Germline variants in SDHB/C/D (SDHx) genes account for subsets of CS/CS-like cases, conferring a higher risk of breast and thyroid cancers
Autor:
Gaetano Bulfamante, Stefania Rossi, Laura Fugazzola, Gianmaria Cantoni, Carla Colombo, Sara Badiali, Paolo Beck-Peccoz, Delfina Tosi, Valentina Cirello, Michela Perrino, Luca Poggi, Simone De Leo, Leonardo Vicentini
Publikováno v:
Endocrine-Related Cancer. 20:L7-L10
Autor:
Angela Greco, Paola Romeo, Veronica Catalano, Ettore Seregni, Silvana Pilotti, Maria Grazia Borrello, Marialuisa Sensi, Debora Degl'Innocenti, Giuliana Cassinelli, Eva Tarantino, Marco A. Pierotti, Federica Perrone, Cinzia Lanzi
Publikováno v:
Endocrine-Related Cancer. 20:23-37
Thyroid carcinomas derived from follicular cells comprise papillary thyroid carcinoma (PTC), follicular thyroid carcinoma, poorly differentiated thyroid carcinoma (PDTC) and undifferentiated anaplastic thyroid carcinoma (ATC). PTC, the most frequent
Autor:
Mingzhao Xing, Ali S Alzahrani
Publikováno v:
Endocrine-Related Cancer. 20:13-22
The impact of metastasized cervical lymph nodes (CLN) identified on central neck dissection (CND) on the recurrence/persistence of papillary thyroid cancer (PTC) and the extent of CND needed to reduce recurrence/persistence have not been firmly estab
Autor:
Heinrich Vierhapper, Christian Bieglmayer, Oskar A. Haas, Bruno Niederle, Christian Scheuba, Ralph Drosten, Anne Moritz, Klaus Kaserer
Publikováno v:
Endocrine-Related Cancer. 16:243-253
‘Calcitonin screening’ is not accepted as the standard of care in daily practice. The clinical and surgical consequences of ‘calcitonin screening’ in a series of patients with mildly elevated basal calcitonin and pentagastrin stimulated calci
Publikováno v:
Endocrine Related Cancer. 15:1069-1074
Thyroid cancers are infiltrated with tumor-associated macrophages (TAMs), yet their role in cancer progression is not known. The objectives of this study were to characterize the density of TAMs in well-differentiated (WDTC), poorly differentiated (P
Autor:
Nimrod B Kiss, Amy Y. M. Au, Catharina Larsson, Åke Borg, Jia-Jing Lee, Michela Barbaro, Theodoros Foukakis, Leigh Delbridge, Johan Staaf, Göran Wallin, Bruce G. Robinson, Anders Höög, Roderick J. Clifton-Bligh
Publikováno v:
Endocrine Related Cancer. 15:801-815
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive disease with largely unexplained etiology and molecular pathogenesis. In this study, we analyzed genome-wide copy number changes, BRAF (V-raf sarcoma viral oncogene homolog B1) mutations