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of 2
pro vyhledávání: '"John C. Byrd"'
Autor:
Hannah Phillips, Rosa Lapalombella, Shaneice Mitchell, Sidney Smith, Payal Desai, Matthew Cannon, Kristina Landes, John C. Byrd
Publikováno v:
Experimental Hematology & Oncology
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-5 (2021)
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-5 (2021)
The in vitro erythrocyte differentiation model remains a strong, clinically relevant tool to model erythroid development in normal and disease related hematopoiesis. This model also has application to developing therapeutics for diseases related to r
Autor:
Zachary A. Hing, Jennifer A. Woyach, Katie Williams, Kerry A. Rogers, Brian Giacopelli, Neil E. Kay, Jordan M. Baumhardt, Matthew K. Summers, Benjamin R. Stromberg, Sameer A. Parikh, Sharon Shacham, Janek S. Walker, Christopher C. Oakes, Rosa Lapalombella, Vincenzo Coppola, Thomas J. Kipps, Qingxiang Sun, Bonnie K. Harrington, Hatice Gulcin Ozer, Larry Beaver, Laura Z. Rassenti, Amy Lehman, Jordan N. Skinner, Yuh Min Chook, Casey Cempre, Lynne V. Abruzzo, John C. Byrd
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Journal of hematology & oncology, vol 14, iss 1
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-21 (2021)
Journal of hematology & oncology, vol 14, iss 1
BackgroundExportin 1 (XPO1/CRM1) is a key mediator of nuclear export with relevance to multiple cancers, including chronic lymphocytic leukemia (CLL). Whole exome sequencing has identified hot-spot somaticXPO1point mutations which we found to disrupt