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Publikováno v:
BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-17 (2021)
Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creat
Autor:
Baoli Heng, Long Qian, Xiao-Qiao Chen, You-Zhen Feng, Qi-Ting Lin, Xiang-Ran Cai, Zhong-Yuan Cheng, Rui Cao, Ding-Kun Si-Tu, Ping-Kang Chen
Publikováno v:
BMC Nephrology
BMC Nephrology, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Nephrology, Vol 22, Iss 1, Pp 1-12 (2021)
Background The current study investigated the performance of intravoxel incoherent motion diffusion (IVIM) technology in monitoring early renal injury in streptozotocin rats. Methods Forty-eight Sprague-Dawley (SD) rats were divided into a control gr
Autor:
Katsuhisa Sunada, Rui Sasaki
Publikováno v:
BMC Oral Health
BMC Oral Health, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Oral Health, Vol 21, Iss 1, Pp 1-7 (2021)
BackgroundWe investigated the role of epinephrine in prolonging the localization of lidocaine on the oral mucosa and inhibiting its absorption in the blood of rats.MethodsWe used 7–8-week-old pathogen-free Wistar male rats (n = 128) for our study.
Autor:
Jia-Kang Fang, Faming Tian, Yun-Peng Hu, Qiangqiang Lian, Liu Zhang, Qi Sun, Fang Liu, Zhuang Zhou
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Background Although adjacent segmental intervertebral disc degeneration (ASDD) is one of the most common complications after lumbar fusion, its exact mechanism remains unclear. As an antibody to RANKL, denosumab (Dmab) effectively reduces bone resorp
Autor:
Mohsen Foadoddini, Samaneh Nakhaee, Bruno Mégarbane, Alireza Amirabadizadeh, Masoumeh Askari, Jeffrey Brent, Ebrahim Miri-Moghaddam, Omid Mehrpour, Khadijeh Farrokhfall
Publikováno v:
Behavioral and Brain Functions : BBF
Behavioral and Brain Functions
Behavioral and Brain Functions, 2021, 17 (1), pp.5. ⟨10.1186/s12993-021-00178-w⟩
Behavioral and Brain Functions, Vol 17, Iss 1, Pp 1-12 (2021)
Behavioral and Brain Functions
Behavioral and Brain Functions, 2021, 17 (1), pp.5. ⟨10.1186/s12993-021-00178-w⟩
Behavioral and Brain Functions, Vol 17, Iss 1, Pp 1-12 (2021)
Background Tramadol is a widely used synthetic opioid. Substantial research has previously focused on the neurological effects of this drug, while the efficacy of various treatments to reduce the associated side effects has not been well studied. Thi
Autor:
Marzieh Naderishahab, Zahra Ebrahimi, Seyed Asaad Karimi, Nazanin Kahvandi, Alireza Komaki, Abdolrahman Sarihi
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 22, Iss 1, Pp 1-10 (2021)
BMC Neuroscience, Vol 22, Iss 1, Pp 1-10 (2021)
Background Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glutamate receptors (mGluRs) in NA
Publikováno v:
BMC Anesthesiology
BMC Anesthesiology, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Anesthesiology, Vol 21, Iss 1, Pp 1-10 (2021)
Background Acute postoperative pain plays an important role in the perioperative neurocognitive disorders (PND). The pathogenesis of PND is still unknown, but it is generally believed that peripheral and central nervous system inflammation play an im
Autor:
Jing Wu, Mingqing Huang, Kewei Fang, Xin Gou, Tongxin Yang, Guiqing Li, Tao Chen, Yuting Weng
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-1 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-1 (2021)
Diabetic bladder disease is common complications of diabetes, its symptoms are diverse, can be due to different stages. In this study we investigate the mechanism of miR-128 targeting CB1 expression to mediate the occurrence of diabetic bladder disea
Publikováno v:
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-11 (2021)
Background Otostegia integrifolia Benth. (Lamiaceae) leaves are used to treat hypertension in Ethiopian folk medicine. However, the claim has so far not been investigated scientifically. Thus, the objective of this study was to evaluate the antihyper
Publikováno v:
Journal of Ovarian Research
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-10 (2021)
Journal of Ovarian Research, Vol 14, Iss 1, Pp 1-10 (2021)
Background Polycystic ovary syndrome (PCOS) is the most common complex endocrine disorder affecting approximately 2–20% of reproductive aged females. Tumour Treating Fields (100–300 kHz) is a recent innovative, non-invasive therapeutic approach t