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Autor:
Marzieh Naderishahab, Zahra Ebrahimi, Seyed Asaad Karimi, Nazanin Kahvandi, Alireza Komaki, Abdolrahman Sarihi
Publikováno v:
BMC Neuroscience
BMC Neuroscience, Vol 22, Iss 1, Pp 1-10 (2021)
BMC Neuroscience, Vol 22, Iss 1, Pp 1-10 (2021)
Background Several studies have shown that glutamate neurotransmission in the nucleus accumbens (NAc) is required for the development of morphine-induced conditional place preference (CPP). In addition, metabotropic glutamate receptors (mGluRs) in NA
Autor:
Zhian Liu, Jing Liu, Zixuan Gao, Ruiqin Yao, Ping Fu, Xiaonan Yan, Lei Wang, Yuhang Ge, Xiaochen Ma
Publikováno v:
Journal of Ovarian Research
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-11 (2020)
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-11 (2020)
The exact pathogenesis of polycystic ovary syndrome (PCOS), the most common neuroendocrine disorder in women of reproductive age, has not been fully elucidated. Recent studies suggested that chronic inflammation and neurotransmitter disorder involved
Autor:
Yu-Ju Lin, Mao-Meng Tiao, Jiunn-Ming Sheen, Ching-Chou Tsai, Hong-Ren Yu, Shih-Wen Li, Kai-Sheng Hsieh, I-Chun Lin, Li-Tung Huang, Chih-Cheng Chen, You-Lin Tain
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-10 (2018)
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-10 (2018)
Background Hypertension may result from high-fat (HF) diet induced-obesity and overexposure to glucocorticoids in utero. Recent studies demonstrated the potent contribution of adipose tissue’s renin-angiotensin system (RAS) to systemic RAS, which p
Publikováno v:
Journal of Biomedical Science
Background Recently, NAD+ has been considered as an essential factor, participating in nerve control of physiological functions and intercellular communication. NAD+ also has been supposed as endogenous activator of P1 and P2 purinoreceptors. Effects
Autor:
Therese H. Røst, Andre Madsen, Gunnar Mellgren, Jennifer Gjerde, Ernst A. Lien, Oddrun Anita Gudbrandsen, Marianne Hauglid Flågeng, Line Leonora Haugan Moi
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 247 (2012)
BMC Cancer, Vol 12, Iss 1, p 247 (2012)
Background Steroid receptor coactivators (SRCs) may modulate estrogen receptor (ER) activity and the response to endocrine treatment in breast cancer, in part through interaction with growth factor receptor signaling pathways. In the present study th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00b28bb45540c37ffeae7334b443c84
https://hdl.handle.net/1956/8718
https://hdl.handle.net/1956/8718
Publikováno v:
Journal of Neuroinflammation
Background Acetate supplementation reduces neuroglia activation and pro-inflammatory cytokine expression in rat models of neuroinflammation and Lyme neuroborreliosis. Because single-dose glyceryl triacetate (GTA) treatment increases brain phosphocrea
Publikováno v:
Respiratory Research
Background Peroxisome proliferator-activated receptor-gamma (PPARγ) is a ligand-activated transcription factor that exerts multiple biological effects. Growing evidence suggests that PPARγ plays an important role in inflammation; however, the effec
Autor:
John J. Renger, Leon Yao, Mark Stiteler, Joseph Brunner, Jacquelyn Binns, Ka Lai Yee, Terrence P. McDonald, Jason M. Uslaner, Paul J. Coleman, Anthony L. Gotter, Joanne Stevens, Charles M. Harrell, Steven V. Fox, Donghui Cui, Christopher J. Winrow, Alan T. Savitz, Spencer J. Tye, Pamela L. Tannenbaum, Scott D. Kuduk, Susan L. Garson
Publikováno v:
BMC Neuroscience
Background Drugs targeting insomnia ideally promote sleep throughout the night, maintain normal sleep architecture, and are devoid of residual effects associated with morning sedation. These features of an ideal compound are not only dependent upon p
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 18, Iss 1, p 31 (2011)
Journal of Biomedical Science, Vol 18, Iss 1, p 31 (2011)
Background- Hypoxia during the first week of life can induce neuronal death in vulnerable brain regions usually associated with an impairment of cognitive function that can be detected later in life. The neurobiological changes mediated through neuro
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 16, Iss 1, p 99 (2009)
Journal of Biomedical Science, Vol 16, Iss 1, p 99 (2009)
Metabotrophic glutamate receptors (mGluRs) modulate cellular activities involved in the processes of differentiation and degeneration. In this study, we have analysed the expression pattern of group-I metabotropic glutamate receptor (mGlu-5) in cereb