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Autor:
Sang-Bae Yoo, Marianne Cunnington, Vanessa Cortes, Rachel H. Bhak, Mei Sheng Duh, Diane Miller, Hwancheol Son, Zrinka Lulic, Suna Park, Pratiksha Kapse
Publikováno v:
BMC Urology
BMC Urology, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Urology, Vol 21, Iss 1, Pp 1-10 (2021)
Objective To assess the use and safety of free combination therapy (dutasteride and tamsulosin), dutasteride monotherapy, or tamsulosin monotherapy in patients with benign prostatic hyperplasia (BPH). Methods This non-interventional retrospective coh
Autor:
Jannie M.B. Sand, Nils Hoyer, Morten A. Karsdal, Thomas Skovhus Prior, Saher B. Shaker, Elisabeth Bendstrup, Peder Frederiksen, Diana Julie Leeming, Henrik Jessen, Sarah Rønnow
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, 382 . https://doi.org/10.1186/s12890-021-01684-3
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, no. 1, 382 . https://doi.org/10.1186/s12890-021-01684-3
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, 382 . https://doi.org/10.1186/s12890-021-01684-3
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, no. 1, 382 . https://doi.org/10.1186/s12890-021-01684-3
Background Remodeling of the extracellular matrix (ECM) is a central mechanism in the progression of idiopathic pulmonary fibrosis (IPF), and remodeling of type VI collagen has been suggested to be associated with disease progression. Biomarkers that
Autor:
Paul W. Jones, David A. Lipson, Leif Bjermer, Claus Vogelmeier, Isabelle Boucot, Edward Kerwin, François Maltais, Chris Compton, Lee Tombs
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Background In patients with chronic obstructive pulmonary disease (COPD), the relationship between short-term bronchodilator reversibility and longer-term response to bronchodilators is unclear. Here, we investigated whether the efficacy of long-acti
Autor:
Tomoko Minamisaka, Yukinori Shinoda, Tetsuya Watanabe, Souki Inoue, Keisuke Ueno, Kentaro Mine, Hirooki Inui, Hidetada Fukuoka, Koichi Tachibana, Shiro Hoshida
Publikováno v:
BMC Cardiovascular Disorders
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-7 (2021)
Background Atrial fibrillation (AF) may cause cerebral and systemic embolism. An increased D-dimer level indicates hyperactivation of secondary fibrinolysis, resulting in predilection for thrombosis. To clarify the differential effects of anticoagula
Autor:
Maria Cristina de Oliveira Izar, Francisco Antonio Helfenstein Fonseca, Ana Paula de Queiroz Mello, Amanda Santoro Fonseca Bacchin, Carolina Nunes França, Antônio Martins Figueiredo Neto, Leticia C. S. Pinto, Flavio T. Moreira, Rui Póvoa, Nágila Raquel Teixeira Damasceno, Adriano Caixeta, Henrique Tria Bianco
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Background Large observational studies have shown that small, dense LDL subfractions are related to atherosclerotic cardiovascular disease. This study assessed the effects of two highly effective lipid-lowering therapies in the atherogenic subclasses
Autor:
Celine R. M. van Latum, Jeroen Schouten, Matthijs Kox, Noortje F. van Kempen, Tim Frenzel, Peter Pickkers, Emma J. Kooistra, Maarten van den Berg, Niklas Bruse, Miranda van Berkel
Publikováno v:
Critical Care
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
BackgroundProcalcitonin (PCT) and C-reactive protein (CRP) were previously shown to have value for the detection of secondary infections in critically ill COVID-19 patients. However, since the introduction of immunomodulatory therapy, the value of th
Autor:
Kazuma Kishi, Natsumi Watanabe, Hirotaka Ono, Masahiro Ando, Eiyasu Tsuboi, Keishi Sugino, Sakae Homma
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Background Although antifibrotic drugs, including nintedanib and pirfenidone, slow the progression of idiopathic pulmonary fibrosis (IPF), there is little data about the timing of start of antifibrotic treatment in real-world clinical practice. The p
Publikováno v:
Critical Care
Critical Care, Vol 25, Iss 1, Pp 1-8 (2021)
Critical Care, Vol 25, Iss 1, Pp 1-8 (2021)
Background Acute kidney injury (AKI) is a common and serious complication after cardiac surgery, and current strategies aimed at treating AKI have proven ineffective. Levosimendan, an inodilatating agent, has been shown to increase renal blood flow a
Autor:
Takamasa Nukui, Isao Kitajima, Hirofumi Konishi, Noriyuki Matsuda, Nobuhiro Dougu, Tomoyuki Sugimoto, Ryoko Anada, Atsushi Matsui, Hideki Niimi, Mamoru Yamamoto, Yuji Nakatsuji, Tomohiro Hayashi
Publikováno v:
BMC Neurology
BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)
Background Extracellular adenosine 5'-triphosphate (ATP) has been suggested to cause neuroinflammation and motor neuron degeneration by activating microglia and astrocytes in amyotrophic lateral sclerosis (ALS). Since we have developed a highly sensi
Autor:
Amy Kolwaite, Charatdao Bunthi, Nora Chea, Noppavan Janejai, Meghan Lyman, Caitlin Biedron, Wantana Paveenkittiporn
Publikováno v:
Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-8 (2021)
Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-8 (2021)
Background Carbapenem-resistant Enterobacterales (CRE) is a global threat. Enterobacterales develops carbapenem resistance through several mechanisms, including the production of carbapenemases. We aim to describe the prevalence of Carbapenem-resista