Zobrazeno 1 - 10
of 42
pro vyhledávání: ''
Autor:
Pamela R. Soulos, Kerin B. Adelson, Mariya Rozenblit, Sarah S. Mougalian, Lajos Pusztai, Sophia Mun
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
BackgroundThere is currently no clinical trial data regarding the efficacy of everolimus exemestane (EE) following prior treatment with CDK4/6 inhibitors (CDK4/6i). This study assesses the use and efficacy of everolimus exemestane in patients with me
Autor:
Takashi Seto, Masashi Kimura, Y. Kogure, Kenichi Suzuki, Toshinobu Hayashi, Mototsugu Shimokawa, Tomomi Takiguchi, Takeshi Koike, Satoru Shimizu, Makoto Nishio, Reiko Matsui, Tomohiko Harada, Kimiko Fujiwara, Naoyuki Nogami, Hirotsugu Kenmotsu, Koichi Goto, Hiroyasu Kaneda
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
Background Of patients receiving moderate emetic risk chemotherapy (MEC), 30–90% experience chemotherapy-induced nausea and vomiting (CINV); however, the optimal antiemetic treatment remains controversial. Methods In this multicenter, prospective,
Autor:
Guofeng Chen, Yinghua Li, Xiao-Ning Gao, Yin Zhang, Yi-Gai Ma, Kai Sun, Sujun Gao, Zhuogang Liu, Lixin Wang, Xin Wang, Jian-Liang Shen, Hui Liu, Li Yu, Lin-Hua Yang, Wei Zhou, Xinquan Li, Xudong Wei, Mei-Yun Fang, Jianmin Luo
Publikováno v:
Clinical Epigenetics
Background Epigenetic mechanisms play an important role in the chemoresistance of acute myeloid leukemia (AML). The clinical response to epigenetic modifier-based chemotherapy in patients with relapsed/refractory AML (r/r AML) is unclear. This multic
Autor:
Manase Kilonzi, George M. Bwire, Christina Malichewe, Omary Minzi, Alphonce I. Marealle, Francis F. Furia, Tatu E. Lyimo
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
Background Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte derangement. The aim of this study was to evaluate the effect of electrolyte supplementation in redu
Autor:
Sudhir Gawariker, Johan Ursing, Andreas Mårtensson, Ashish Pathak, Manju Purohit, Ashish Ranjan Sharma, Vishal Diwan
Publikováno v:
Malaria Journal
Malaria Journal, Vol 19, Iss 1, Pp 1-7 (2020)
Malaria Journal, Vol 19, Iss 1, Pp 1-7 (2020)
Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-8 (2020)
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-8 (2020)
Background Hyponatremia, a marker of disease severity and prognosis, has been associated with various clinical factors and drug use, especially diuretics. Methods This observational prospective cohort study enrolled patients hospitalized at the Unive
Autor:
Narmada Fernando, Senaka Rajapakse, H. N. Ranasinghe, Prasad Katulanda, Priyadarshani Galappatthy, Godwin R Constantine, Praveen Weeratunga, Shiroma M. Handunnetti
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 13, Iss 1, Pp 1-5 (2020)
BMC Research Notes, Vol 13, Iss 1, Pp 1-5 (2020)
Objectives The objective was to assess the effect of propranolol on oxidative stress and anti-oxidant potential in patients with resistant hypertension as a secondary analysis of the APPROPRIATE trial. This randomized double blinded clinical trial re
Publikováno v:
BMC Ophthalmology
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020)
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-7 (2020)
Background The EVEREST II study reported superior polyp closure rates and visual outcomes using combination standard photodynamic therapy (PDT) with intravitreal ranibizumab in the treatment of polypoidal choroidal vasculopathy (PCV). The optimal PDT
Autor:
Sergio Vázquez, Jose Miguel Cuevas Sanz, A. González-del-Alba, Alvaro Pinto, Jacobo Muñoz del Toro, Ángela García García-Porrero, Ángel Francisco Zazo Rodríguez, Javier Puente, Eduardo Useros Rodríguez, Núria Sala-González, María José Méndez-Vidal
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Background To describe the patterns of second-line treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) after docetaxel treatment in a Spanish population, to identify the factors associated with those patterns, and to co
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-6 (2019)
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-6 (2019)
Background Concern about intoxication by e-liquid is growing as calls to poison control centers have increased since their introduction. Only three cases of intoxication by injection have been reported worldwide. Our case is unique because of the pre