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Autor:
Jannie M.B. Sand, Nils Hoyer, Morten A. Karsdal, Thomas Skovhus Prior, Saher B. Shaker, Elisabeth Bendstrup, Peder Frederiksen, Diana Julie Leeming, Henrik Jessen, Sarah Rønnow
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, 382 . https://doi.org/10.1186/s12890-021-01684-3
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, no. 1, 382 . https://doi.org/10.1186/s12890-021-01684-3
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021)
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, 382 . https://doi.org/10.1186/s12890-021-01684-3
Jessen, H, Hoyer, N, Prior, T S, Frederiksen, P, Rønnow, S R, Karsdal, M A, Leeming, D J, Bendstrup, E, Sand, J M B & Shaker, S B 2021, ' Longitudinal serological assessment of type VI collagen turnover is related to progression in a real-world cohort of idiopathic pulmonary fibrosis ', BMC Pulmonary Medicine, vol. 21, no. 1, 382 . https://doi.org/10.1186/s12890-021-01684-3
Background Remodeling of the extracellular matrix (ECM) is a central mechanism in the progression of idiopathic pulmonary fibrosis (IPF), and remodeling of type VI collagen has been suggested to be associated with disease progression. Biomarkers that
Autor:
Maria Cristina de Oliveira Izar, Francisco Antonio Helfenstein Fonseca, Ana Paula de Queiroz Mello, Amanda Santoro Fonseca Bacchin, Carolina Nunes França, Antônio Martins Figueiredo Neto, Leticia C. S. Pinto, Flavio T. Moreira, Rui Póvoa, Nágila Raquel Teixeira Damasceno, Adriano Caixeta, Henrique Tria Bianco
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Background Large observational studies have shown that small, dense LDL subfractions are related to atherosclerotic cardiovascular disease. This study assessed the effects of two highly effective lipid-lowering therapies in the atherogenic subclasses
Autor:
Celine R. M. van Latum, Jeroen Schouten, Matthijs Kox, Noortje F. van Kempen, Tim Frenzel, Peter Pickkers, Emma J. Kooistra, Maarten van den Berg, Niklas Bruse, Miranda van Berkel
Publikováno v:
Critical Care
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
BackgroundProcalcitonin (PCT) and C-reactive protein (CRP) were previously shown to have value for the detection of secondary infections in critically ill COVID-19 patients. However, since the introduction of immunomodulatory therapy, the value of th
Autor:
Kazuma Kishi, Natsumi Watanabe, Hirotaka Ono, Masahiro Ando, Eiyasu Tsuboi, Keishi Sugino, Sakae Homma
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Background Although antifibrotic drugs, including nintedanib and pirfenidone, slow the progression of idiopathic pulmonary fibrosis (IPF), there is little data about the timing of start of antifibrotic treatment in real-world clinical practice. The p
Autor:
Takamasa Nukui, Isao Kitajima, Hirofumi Konishi, Noriyuki Matsuda, Nobuhiro Dougu, Tomoyuki Sugimoto, Ryoko Anada, Atsushi Matsui, Hideki Niimi, Mamoru Yamamoto, Yuji Nakatsuji, Tomohiro Hayashi
Publikováno v:
BMC Neurology
BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Neurology, Vol 21, Iss 1, Pp 1-8 (2021)
Background Extracellular adenosine 5'-triphosphate (ATP) has been suggested to cause neuroinflammation and motor neuron degeneration by activating microglia and astrocytes in amyotrophic lateral sclerosis (ALS). Since we have developed a highly sensi
Autor:
Pamela R. Soulos, Kerin B. Adelson, Mariya Rozenblit, Sarah S. Mougalian, Lajos Pusztai, Sophia Mun
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
BackgroundThere is currently no clinical trial data regarding the efficacy of everolimus exemestane (EE) following prior treatment with CDK4/6 inhibitors (CDK4/6i). This study assesses the use and efficacy of everolimus exemestane in patients with me
Autor:
Takashi Seto, Masashi Kimura, Y. Kogure, Kenichi Suzuki, Toshinobu Hayashi, Mototsugu Shimokawa, Tomomi Takiguchi, Takeshi Koike, Satoru Shimizu, Makoto Nishio, Reiko Matsui, Tomohiko Harada, Kimiko Fujiwara, Naoyuki Nogami, Hirotsugu Kenmotsu, Koichi Goto, Hiroyasu Kaneda
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
Background Of patients receiving moderate emetic risk chemotherapy (MEC), 30–90% experience chemotherapy-induced nausea and vomiting (CINV); however, the optimal antiemetic treatment remains controversial. Methods In this multicenter, prospective,
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-5 (2020)
Journal of Medical Case Reports, Vol 14, Iss 1, Pp 1-5 (2020)
Background Lithium carbonate is widely used as a first-line therapeutic agent for the depressive and manic phases of bipolar disorder. Although limb tremors and hypothyroidism are well-known side effects of lithium carbonate, other rare adverse react
Autor:
Manase Kilonzi, George M. Bwire, Christina Malichewe, Omary Minzi, Alphonce I. Marealle, Francis F. Furia, Tatu E. Lyimo
Publikováno v:
BMC Pharmacology & Toxicology
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
Background Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte derangement. The aim of this study was to evaluate the effect of electrolyte supplementation in redu
Autor:
George Kamkamidze, Shorena Dvali, Amiran Gamkrelidze, David Metreveli, Lia Gvinjilia, Juliette Morgan, Muazzam Nasrullah, Francisco Averhoff, Tamar Rukhadze, Maia Butsashvili, Shaun Shadaker
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 13, Iss 1, Pp 1-4 (2020)
BMC Research Notes, Vol 13, Iss 1, Pp 1-4 (2020)
Background: In 2015, Georgia launched world’s first HCV elimination program. Initially, patients with advanced liver disease were prioritized to receive sofosbuvir-based treatment regimen, as it was the only DAA available for all genotypes. Purpose