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Autor:
Qi-Long Cao, Dian-Han Zhang, Chen-Hui Zhu, Jing Xu, Chuanlong Guo, Chen-Wei Zhu, Xianggen Wu, Guohu Di
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
End-stage liver disease (ESLD) is characterized by the deterioration of liver function and a subsequent high mortality rate. Studies have investigated the use of adult stem cells to treat ESLD. Here, a systematic review and meta-analysis was conducte
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Chimeric antigen receptor T-cell (CAR-T) therapy has been prosperous in the treatment of patients with various types of relapsed/refractory (R/R) B-cell malignancies including diffuse large B-cell lymphoma (DLBCL), B-cell acute lymphoblastic leukemia
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Achondroplasia (ACH) is the most common genetic form of dwarfism and belong to dominant monogenetic disorder (MGD) caused by a gain-of-function point mutation in the transmembrane region of fibroblast growth factor receptor 3 (FGFR3). There are curre
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Fat tissue (FT) has been used for many years in regenerative surgery as a bioactive material through the lipofilling/fat graft (F-GRF)–nano-fat technique, as a bioactive scaffold when it was enriched with adipose-derived mesenchymal stem c
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Background Surfactant therapy is a standard of care for preterm infants with respiratory distress and reduces the incidence of death and bronchopulmonary dysplasia in these patients. Our previous study found that mesenchymal stem cells (MSCs) attenua
Autor:
Ling Wei, Lihua Wang, Wei Sun, Qin Xie, Teng Li, Shuangnian Xu, Chengxin Luo, Jiasi Zhang, Yongli Zhao, Yan Liu
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-22 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-22 (2021)
Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is life-saving for severe hematological conditions. However, its outcomes need further improvement, and co-infusion of mesenchymal stem cells (MSCs) may show promise. A growing
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Background Mesenchymal stromal cells (MSCs) are an emerging prophylaxis option for graft-versus-host disease (GVHD) in haplo-identical hematopoietic stem cell transplantation (haplo-HSCT) recipients with severe aplastic anemia (SAA), but studies have
Autor:
Acharaporn Dambua, Areerat Khorchai, Adisak Trinavarat, Aekkachai Tuekprakhon, Phitchapa Pongpaksupasin, Patcharaporn Boonchu, Mongkol Uiprasertkul, Chonlada Yodtup, Panya Luksanapruksa, La-ongsri Atchaneeyasakul, Monchai Ruangchainikom, Somchai Sangkitporn, Aulia Rahmi Pawestri, Visit Vamvanij, Siripakorn Sangkitporn
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Background Retinitis pigmentosa (RP) is a progressive inherited retinal disease with great interest for finding effective treatment modalities. Stem cell-based therapy is one of the promising candidates. We aimed to investigate the safety, feasibilit
Autor:
Wensong Li, Jisheng Wang, Zhenhong Liu, Jiang Yu, Guocai Cai, Yong Yang, Runfeng Zhang, Ningkun Zhang, Yu Chen
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)
Objective Our aim was to evaluate the efficacy and safety of intracoronary autologous bone marrow mesenchymal stem cell (BM-MSC) transplantation in patients with ST-segment elevation myocardial infarction (STEMI). Methods In this randomized, single-b
Autor:
Dapeng Li, Qiping Zheng, Lianghao Mao, Chenlie Ni, Bing Zhang, Pan Jiang, Yiming Zhang, Xuan Lei
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Background Osteonecrosis of femoral head (ONFH) is a seriously degenerative disease with no effective therapies to slow its progression. Several studies have reported short-term efficacy of stem cells on early-stage ONFH. However, its long-term effec