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Autor:
Kritika Yadav, Emre Ozcekirdek, Goar Egoryan, Ece Ozen, Tianyu Dong, Guillermo Rodriguez-Nava, Sana Chaudry
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Background Rhabdomyolysis is defined as a syndrome consisting of muscle necrosis and the release of intracellular muscle components into the bloodstream. Although rhabdomyolysis has been previously reported as an initial presentation or late complica
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
Background Individuals with relapses of leprosy should be monitored carefully, however, with respect to paucibacillary (PB) leprosy, it is sometimes difficult to make a definitive diagnosis of relapse, because the bacillary index is often negative. T
Autor:
Martin A. Javors, Adam R. Konopka, Dennis M. Minton, Kelly S. Santangello, Christian J. Elliehausen
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Background The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA. Design Dunkin-Hartley guinea pigs
Autor:
Awad Saad Abbas, Asiful Islam, Abdelhfeez Moshrif, Wesam Gouda, Faisal Alsaqabi, Tarek M. Abdel-Aziz
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s d
Autor:
Ricardo Blanco, Sibylle Haemmerle, Atul Deodhar, Hideto Kameda, Stephen Hall, Marleen G H van de Sande, Helena Marzo-Ortega, Jürgen Braun, Denis Poddubnyy, Abhijit Shete, Anna Wiksten, Brian Porter, Hanno B. Richards, Lianne S. Gensler, Filip Van den Bosch
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Arthritis research & therapy, 23(1):231. BioMed Central
ARTHRITIS RESEARCH & THERAPY
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Arthritis research & therapy, 23(1):231. BioMed Central
ARTHRITIS RESEARCH & THERAPY
Background To investigate the efficacy of secukinumab in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) grouped by disease activity as assessed by C-reactive protein (CRP) levels and/or magnetic resonance imaging (MRI) score
Autor:
Makaramas Anantaburana, Orawin Vallibhakara, Siriluk Tantanavipas, Apirom Vongsakulyanon, Sakda Arj-Ong Vallibhakara, Woradej Hongsakorn, Wichai Ittichaikulthol, Srithean Lertvikool, Krissada Paiwattananupant, Prangthip Akkaranurakkul, Areepan Sophonsritsuk
Publikováno v:
Pilot and Feasibility Studies
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-10 (2021)
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-10 (2021)
Background Strategies to preserve ovarian function after ovarian endometriotic cyst removal have been reported in many studies; however, no study has evaluated tranexamic acid administration during surgery. Objective To evaluate feasibility of conduc
Autor:
Kenneth Krohn, Darrin Byrd, Robert K. Doot, Lanell M. Peterson, Alena Novakova-Jiresova, Perrin E. Romine, Hannah M. Linden, Mark Muzi, David A. Mankoff, Brenda F. Kurland, Jennifer M. Specht, Jeanne M. Link, Paul E. Kinahan
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
PurposeThis study evaluated the ability of18F-Fluorodeoxyglucose (FDG) and18F-Fluorothymidine (FLT) imaging with positron emission tomography (PET) to measure early response to endocrine therapy from baseline to just prior to surgical resection in es
Autor:
Severin Vogt, Sarah Dräger, Carmen Volken, Jörg D. Leuppi, Beat Mueller, Jonas Rutishauser, Marten Trendelenburg, Philipp Schuetz, Michael Osthoff
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
BackgroundThe innate and adaptive immune system is involved in the airway inflammation associated with acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). We evaluated the association of mannose-binding lectin (MBL), im
Autor:
Chrysostomi Gialeli, Johan Staaf, Safia Guleed, Matthias Mörgelin, Anna M. Blom, Emre Can Tuysuz, Konstantinos S. Papadakos, Veronika Paciorek
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-21 (2021)
Background Human CUB and Sushi multiple domains 1 (CSMD1) is a large membrane-bound tumor suppressor in breast cancer. The current study aimed to elucidate the molecular mechanism underlying the effect of CSMD1 in highly invasive triple negative brea
Autor:
Daniel P. Hollern, Shanta P. Boddapati, Ting Zheng, S. Watson, Joseph P. Garay, James E. Korkola, Joe W. Gray, Koei Chin, Moqing Liu, Rebecca Smith, Sunjong Kwon, Laura M. Heiser, Wallace Thompson, Darcie Babcock, Amanda Esch, Kaylyn Devlin, Tiera Liby
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Background HER2-amplified breast cancer is a clinically defined subtype of breast cancer for which there are multiple viable targeted therapies. Resistance to these targeted therapies is a common problem, but the mechanisms by which resistance occurs