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Autor:
Kritika Yadav, Emre Ozcekirdek, Goar Egoryan, Ece Ozen, Tianyu Dong, Guillermo Rodriguez-Nava, Sana Chaudry
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-5 (2021)
Background Rhabdomyolysis is defined as a syndrome consisting of muscle necrosis and the release of intracellular muscle components into the bloodstream. Although rhabdomyolysis has been previously reported as an initial presentation or late complica
Autor:
Martin A. Javors, Adam R. Konopka, Dennis M. Minton, Kelly S. Santangello, Christian J. Elliehausen
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-14 (2021)
Background The objective of this study was to determine if mechanistic target of rapamycin (mTOR) inhibition with or without AMP-activated protein kinase (AMPK) activation can protect against primary, age-related OA. Design Dunkin-Hartley guinea pigs
Autor:
Awad Saad Abbas, Asiful Islam, Abdelhfeez Moshrif, Wesam Gouda, Faisal Alsaqabi, Tarek M. Abdel-Aziz
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s d
Autor:
Ricardo Blanco, Sibylle Haemmerle, Atul Deodhar, Hideto Kameda, Stephen Hall, Marleen G H van de Sande, Helena Marzo-Ortega, Jürgen Braun, Denis Poddubnyy, Abhijit Shete, Anna Wiksten, Brian Porter, Hanno B. Richards, Lianne S. Gensler, Filip Van den Bosch
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Arthritis research & therapy, 23(1):231. BioMed Central
ARTHRITIS RESEARCH & THERAPY
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
Arthritis research & therapy, 23(1):231. BioMed Central
ARTHRITIS RESEARCH & THERAPY
Background To investigate the efficacy of secukinumab in patients with active non-radiographic axial spondyloarthritis (nr-axSpA) grouped by disease activity as assessed by C-reactive protein (CRP) levels and/or magnetic resonance imaging (MRI) score
Autor:
Makaramas Anantaburana, Orawin Vallibhakara, Siriluk Tantanavipas, Apirom Vongsakulyanon, Sakda Arj-Ong Vallibhakara, Woradej Hongsakorn, Wichai Ittichaikulthol, Srithean Lertvikool, Krissada Paiwattananupant, Prangthip Akkaranurakkul, Areepan Sophonsritsuk
Publikováno v:
Pilot and Feasibility Studies
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-10 (2021)
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-10 (2021)
Background Strategies to preserve ovarian function after ovarian endometriotic cyst removal have been reported in many studies; however, no study has evaluated tranexamic acid administration during surgery. Objective To evaluate feasibility of conduc
Autor:
Kenneth Krohn, Darrin Byrd, Robert K. Doot, Lanell M. Peterson, Alena Novakova-Jiresova, Perrin E. Romine, Hannah M. Linden, Mark Muzi, David A. Mankoff, Brenda F. Kurland, Jennifer M. Specht, Jeanne M. Link, Paul E. Kinahan
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-11 (2021)
PurposeThis study evaluated the ability of18F-Fluorodeoxyglucose (FDG) and18F-Fluorothymidine (FLT) imaging with positron emission tomography (PET) to measure early response to endocrine therapy from baseline to just prior to surgical resection in es
Autor:
Severin Vogt, Sarah Dräger, Carmen Volken, Jörg D. Leuppi, Beat Mueller, Jonas Rutishauser, Marten Trendelenburg, Philipp Schuetz, Michael Osthoff
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
BackgroundThe innate and adaptive immune system is involved in the airway inflammation associated with acute exacerbations in patients with chronic obstructive pulmonary disease (COPD). We evaluated the association of mannose-binding lectin (MBL), im
Autor:
Celine R. M. van Latum, Jeroen Schouten, Matthijs Kox, Noortje F. van Kempen, Tim Frenzel, Peter Pickkers, Emma J. Kooistra, Maarten van den Berg, Niklas Bruse, Miranda van Berkel
Publikováno v:
Critical Care
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
Critical Care, 25
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Critical Care, 25, 1
BackgroundProcalcitonin (PCT) and C-reactive protein (CRP) were previously shown to have value for the detection of secondary infections in critically ill COVID-19 patients. However, since the introduction of immunomodulatory therapy, the value of th
Autor:
Helena Eriksson, Birgitta Sparre, Roger Hesselstrand, Marie Törngren, Gabriela Riemekasten, Dirk M. Wuttge, Jörg H W Distler, Fredrik Andersson, Helén Carlsson Nyhlén, Helén Tuvesson, Oliver Distler
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Objectives To evaluate the changes in disease-related biomarkers and safety of paquinimod, an oral immunomodulatory compound, in patients with systemic sclerosis (SSc). Methods In this open-label, single-arm, multicenter study, SSc patients with a ra
Autor:
Shui-Yi Tung, Chung-Kuang Lu, Chen-Heng Shen, Yu-Ting Huang, Yung-Yu Hsieh, Te-Sheng Chang, Kuo-Liang Wei, Kao-Chi Chang, Sheng-Nan Lu, Chao-Hung Hung, Chih-Wei Yen, Wei-Ming Chen
Publikováno v:
BMC Gastroenterology
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-9 (2021)
Introduction Real-world data regarding the impact of hepatic fibrosis on the effectiveness of sofosbuvir/velpatasvir (SOF/VEL) treatment is limited in the Asian population. Methods We analyzed data for all 823 patients with hepatitis C virus treated