Zobrazeno 31 - 40
of 79
pro vyhledávání: ''
Autor:
Catherine Watson, Dean F. Rigel, Daniel LaSala, Fumin Fu, Michael E. Beil, Sam Rebello, Arco Y. Jeng, Jing Liu, Chii-Whei Hu, William P. Dole, Yiming Zhang, Joël Ménard, Jennifer Leung-Chu, Wei Chen, Guiqing Liang
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, BioMed Central, 2014, 12 (1), pp.340
Journal of Translational Medicine, BioMed Central, 2014, 12 (1), pp.340
Background Aldosterone synthase inhibition provides the potential to attenuate both the mineralocorticoid receptor-dependent and independent actions of aldosterone. In vitro studies with recombinant human enzymes showed LCI699 to be a potent, reversi
Autor:
Jianfeng Ji, Ye Tian, Yuan Zhang, Hongying Yang, Kun Li, Peigeng Huang, Liyuan Zhang, Rui Sun
Publikováno v:
Radiation Oncology (London, England)
Background: It has been long recognized that cranial irradiation used for the treatment of primary and metastatic brain tumor often causes neurological side-effects such as intellectual impairment, memory loss and dementia, especially in children pat
Autor:
Wolfgang Drommer, Catrin Albrecht, Paul Borm, Irene M. J. Eurlings, Niki L. Reynaert, Roel P. F. Schins, Timothy N. Perkins, Paul Peeters, Emiel F.M. Wouters
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, 11(1):58. BioMed Central Ltd
Particle and Fibre Toxicology, 11(1):58. BioMed Central Ltd
Rationale Mineral particles in the lung cause inflammation and silicosis. In myeloid and bronchial epithelial cells the inflammasome plays a role in responses to crystalline silica. Thioredoxin (TRX) and its inhibitory protein TRX-interacting protein
Publikováno v:
BMC Complementary and Alternative Medicine
Background Flavonoid-rich aqueous fraction of methanolic extract of Hibiscus sabdariffa calyx was evaluated for its anti-hepatotoxic activities in streptozotocin-induced diabetic Wistar rats. Methods Diabetes Mellitus was induced in Wistar rats by a
Autor:
Juan José Gagliardino, Ramon Gomis, Jordi Altirriba, Hector Herminio del Zotto, Belen Nadal, Sandra Piquer, Albert Barberà, Alex Sánchez-Pla
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BMC Genomics
BMC Genomics, Vol 10, Iss 1, p 406 (2009)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
BMC Genomics
BMC Genomics, Vol 10, Iss 1, p 406 (2009)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Background: Sodium tungstate is known to be an effective anti-diabetic agent, able to increase beta cell mass in animal models of diabetes, although the molecular mechanisms of this treatment and the genes that control pancreas plasticity are yet to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44fe64dbe17eecabbe1a15073f4b213
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-10-406
https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-10-406
Autor:
Alessandro Fulgenzi, Paolo Ticozzi, Josè S Franzone, Chiara Foglieni, Giacomo Dell'Antonio, Elena Dal Cin, Maria Elena Ferrero
Publikováno v:
BMC Immunology
BMC Immunology, Vol 6, Iss 1, p 18 (2005)
BMC Immunology, Vol 6, Iss 1, p 18 (2005)
Background We previously showed that local use of periodate oxidized ATP (oATP, a selective inhibitor of P2X7 receptors for ATP) in rat paw treated with Freund's adjuvant induced a significant reduction of hyperalgesia Herein we investigate the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d51a638936a8249c40f12a4b2c234d7
http://hdl.handle.net/2434/9970
http://hdl.handle.net/2434/9970
Publikováno v:
BMC Nephrology
Background Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and is associated with excessive cardiovascular morbidity and mortality. The angiotensin converting enzyme inhibitor (ACEI) benazepril has been shown to slow the prog
Publikováno v:
Journal of Neuroinflammation
Background Acetate supplementation reduces neuroglia activation and pro-inflammatory cytokine expression in rat models of neuroinflammation and Lyme neuroborreliosis. Because single-dose glyceryl triacetate (GTA) treatment increases brain phosphocrea
Publikováno v:
Journal of NeuroEngineering and Rehabilitation
Background Recent publications highlight differences within the sub-regions of the ventral tegmental area (VTA) including the parabrachial pigmented nucleus (PBP), parainterfascicular nucleus (PIF) and paranigral nucleus (PN) in the projections to th
Publikováno v:
Journal of Biomedical Science
Background An endogenous dopaminergic (DA) tone acting on D3 receptors has been shown to inhibit tuberoinfundibular (TI) DA neuron activity and stimulate prolactin (PRL) surge in the afternoon of estrogen-primed ovariectomized (OVX+E2) rats. Whether