Zobrazeno 1 - 10
of 92
pro vyhledávání: ''
Publikováno v:
BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-17 (2021)
Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creat
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Background Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in head and neck. Platinum-based chemotherapy is an important treatment for NPC. However, the molecular mechanism of resistance to platinum drug remains unknown. Endopla
Autor:
Jana Plava, Lucia Rojikova, Bozena Smolkova, Lenka Trnkova, Monika Burikova, Pavel Babal, Lubos Danisovic, Svetlana Miklikova, Lucia Kucerova, Pavol Janega, Lucia Krivosikova, Marina Cihova, Martin Bohac, Slávka Drahošová
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Background Chemotherapy remains a standard treatment option for breast cancer despite its toxic effects to normal tissues. However, the long-lasting effects of chemotherapy on non-malignant cells may influence tumor cell behavior and response to trea
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 21, Iss 1, Pp 1-11 (2021)
Cancer Cell International, Vol 21, Iss 1, Pp 1-11 (2021)
Backgrounds As previously reported, midazolam anesthesia exerts tumor-suppressing effects in non-small cell lung cancer (NSCLC), but the regulating effects of this drug on cisplatin-resistance in NSCLC have not been studied. Thus, we designed this st
Autor:
Jing-Qiang Huang, Jun-Wei Song, Qiu-Yu Liu, Liang Wang, Peng Gong, Chun-Hui Zhou, He-Feng Li, Jing Zhu, Li-Yun Gong, Xian-Bin Zhang
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Background Colorectal cancer is the third most common diagnosis. Oxaliplatin is used as first-line treatment of colon cancer. However, oxaliplatin resistance greatly reduces its therapeutic effect. SRPK1 involves in pre-mRNA splicing and tumorigenesi
Autor:
Dongli Sun, Fengmei Wang, Caihong Zheng, Xiaodong Wu, Yunchun Zhao, Yao Yao, Chaoqun Li, Meng Zhang, Jiale Qin, Weidong Fei
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-21 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-21 (2021)
Gestational trophoblastic tumors seriously endanger child productive needs and the health of women in childbearing age. Nanodrug-based therapy mediated by transporters provides a novel strategy for the treatment of trophoblastic tumors. Focusing on t
Autor:
Linbo Wang, Shuduo Xie, Xun Zhang, Ji Wang, Zhaoqing Li, Misha Mao, Aihua Huang, Jichun Zhou, Lini Chen, Noor Ul Hassan Khan, Cong Chen, Jingjing Yang, Yulu Zhou, Yongxia Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-19 (2021)
Background Ferroptosis is a newly defined form of regulated cell death characterized by the iron-dependent accumulation of lipid peroxidation and is involved in various pathophysiological conditions, including cancer. Targeting ferroptosis is conside
Autor:
Wang Shaojia, Miao Xiangshuai, Yan Chen, Li Na, Mingwei Tang, Lei Qing, Wu Zhengwei, Xu Yang, Debing Zhu, Wang Weiwei, Chao Liu
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-10 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-10 (2021)
Background Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, has been used as first-line treatment for advanced non-small-cell lung cancer (NSCLC). However, during treatment, cancer cells often develop resistance to gefitinib,
Autor:
Martha E Cancino-Marentes, Raul Antonio Solis-Martinez, Alejandro Bravo-Cuellar, Pablo C Ortiz-Lazareno, Marı́a Martha Villaseñor-Garcı́a, Erick Sierra-Diaz, Georgina Hernández-Flores, Claudia Carolina Cruz-Gálvez, Eduardo Orozco-Alonso
Publikováno v:
BMC Urology
BMC Urology, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Urology, Vol 21, Iss 1, Pp 1-10 (2021)
Background Prostate cancer is one of the most frequently diagnosed types of cancers worldwide. In its initial period, the tumor is hormone-sensitive, but in advanced states, it evolves into a metastatic castration-resistant tumor. In this state, chem
Autor:
Alireza Mirzaei, Saeed Mehrzadi, Azam Hosseinzadeh, Farid Moradian, Mohammad Hossein Pourhanifeh
Publikováno v:
Cancer Cell International
Cancer Cell International, Vol 21, Iss 1, Pp 1-28 (2021)
Cancer Cell International, Vol 21, Iss 1, Pp 1-28 (2021)
Cancers are serious life-threatening diseases which annually are responsible for millions of deaths across the world. Despite many developments in therapeutic approaches for affected individuals, the rate of morbidity and mortality is high. The survi