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Autor:
Takanori Hazeyama, Mikio Nakamura, Kazuyoshi Uchihashi, Yujo Kawashita, Shigehisa Aoki, Hiroki Moriuchi, Masaki Tateishi, Junzo Yamaguchi, Takashi Ueda
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Background Interactions between adipocyte and breast cancer (BC) cells have yet to be fully elucidated. Here we investigated the prognostic impact of marginal adipose tissue invasion in both luminal breast cancer (HR+/HER2-) and triple-negative breas
Autor:
Ryota Tamura, Yukina Morimoto, Kenzo Kosugi, Mizuto Sato, Yumiko Oishi, Ryo Ueda, Ryogo Kikuchi, Hideaki Nagashima, Tetsuro Hikichi, Shinobu Noji, Yutaka Kawakami, Hikaru Sasaki, Kazunari Yoshida, Masahiro Toda
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Background The expression of vascular endothelial growth factor (VEGF)-A/ VAGF receptors (VEGFRs) signaling plays a pivotal role in the tumor angiogenesis and the development of the immunosuppressive tumor microenvironment in glioblastomas. We have p
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Background The prognostic role of serum alkaline phosphatase (ALP) has been found in several kinds of solid malignant tumor, but has never been extensively discussed in pancreatic cancer, especially through the application of dynamic survival model w
Autor:
Yasuhiro Hiyoshi, Seiichiro Kusuhara, Noriko Nishinarita, Katsuhiko Naoki, Masayuki Shirasawa, Yoshiro Nakahara, Tomoya Fukui, Satoshi Igawa
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Background Small cell lung cancer (SCLC) is characterized by a high propensity for metastases and a poor prognosis irrespective of high sensitivity for initial chemotherapy. Although interstitial pneumonia (IP) is one of risk factors for lung cancer,
Autor:
Liqun Zhou, Guangzhe Ge, Bao Guan, Zhisong He, Yuanyuan Zhou, Xuesong Li, Yanqing Gong, Han Hao, Gengyan Xiong, Yue Shi, Ziying Xu, Ding Peng, Yifan Li, Cuijian Zhang, Shiming He, Yonghao Zhan, Weimin Ci
Publikováno v:
Clinical Epigenetics
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-13 (2018)
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-13 (2018)
Background 5-Hydroxymethylcytosine (5hmC) is converted from 5-methylcytosine (5mC) by a group of enzymes termed ten-eleven translocation (TET) family dioxygenases. The loss of 5hmC has been identified as a hallmark of most types of cancer and is rela
Autor:
Josefine Römmler-Zehrer, Arndt Vogel, Michael Stahl, Alfredo Romano, Jack Shiansong Li, Desmond McGovern
Publikováno v:
BMC Cancer
Background The phase 3 MPACT trial in patients with metastatic pancreatic cancer demonstrated superior efficacy of nab-paclitaxel (nab-P) + gemcitabine (Gem) vs Gem monotherapy for all endpoints examined including overall survival, the primary endpoi
Autor:
Anna M. Bofin, Maria D. Cao, Guro F. Giskeødegård, Ingrid S. Gribbestad, Per Eystein Lønning, Tone Frost Bathen, Beathe Sitter, Steinar Lundgren
Publikováno v:
BMC Cancer
BMC Cancer, Vol 12, Iss 1, p 39 (2012)
BMC Cancer, Vol 12, Iss 1, p 39 (2012)
Background Today's clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor metabolic changes in patients with locally advanced breast cancer caused by neoadjuva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0d03f9f6fcb483aa9940d1b9c21262
http://hdl.handle.net/11250/2621821
http://hdl.handle.net/11250/2621821
Autor:
Brooke L. Fridley, Ryan Abo, Ping Yang, Zhifu Sun, Julie M. Cunningham, Gregory D. Jenkins, Abra Brisbin, Nifang Niu, Liang Li, Anthony Batzler, Krishna R. Kalari, Daniel J. Schaid, Liewei Wang, QiPing Feng
Publikováno v:
BMC Cancer
BioMed Central Ltd
BMC Cancer, Vol 12, Iss 1, p 422 (2012)
BioMed Central Ltd
BMC Cancer, Vol 12, Iss 1, p 422 (2012)
Background: Taxane is one of the first line treatments of lung cancer. In order to identify novel single nucleotide polymorphisms (SNPs) that might contribute to taxane response, we performed a genome-wide association study (GWAS) for two taxanes, pa