Zobrazeno 1 - 10
of 51
pro vyhledávání: ''
Autor:
Jia-Kang Fang, Faming Tian, Yun-Peng Hu, Qiangqiang Lian, Liu Zhang, Qi Sun, Fang Liu, Zhuang Zhou
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-16 (2021)
Background Although adjacent segmental intervertebral disc degeneration (ASDD) is one of the most common complications after lumbar fusion, its exact mechanism remains unclear. As an antibody to RANKL, denosumab (Dmab) effectively reduces bone resorp
Autor:
Jing Wu, Mingqing Huang, Kewei Fang, Xin Gou, Tongxin Yang, Guiqing Li, Tao Chen, Yuting Weng
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-1 (2021)
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-1 (2021)
Diabetic bladder disease is common complications of diabetes, its symptoms are diverse, can be due to different stages. In this study we investigate the mechanism of miR-128 targeting CB1 expression to mediate the occurrence of diabetic bladder disea
Autor:
Hye Ryeong Kim, Minhan Ka, Ri-Na Lim, Joung-Wook Seo, Dae Youn Hwang, Soonil Kim, Tae-Wan Kim, Young Ju Lee, Jeffrey J. Moffat
Publikováno v:
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-15 (2020)
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-15 (2020)
Background Depression is a serious and common psychiatric disorder generally affecting more women than men. A woman’s risk of developing depression increases steadily with age, and higher incidence is associated with the onset of menopause. Here we
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Background Neuropathic pain is related to the sustained activation of neuroglial cells and the production of proinflammatory cytokines in the spinal dorsal horn. However, the clinical efficacy of currently available treatments is very limited. The tr
Autor:
Haoyan Tu, Jun Yao, Rongrong Zhang, Xiaocan Lei, Shun Zhang, Peng Huo, Jianghua Le, Zhengxu Jiang, Qianqian Tang
Publikováno v:
Reproductive Biology and Endocrinology : RB&E
Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-11 (2020)
Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-11 (2020)
Background Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disease with unknown pathogenesis. However, the treatment of Diane-35 combined with metformin can improve the endocrine and ovulation of PCOS. In this study, we investig
Autor:
Kohki Toriuchi, Satoru Takeshita, Yasumasa Yamada, Mineyoshi Aoyama, Tetsuya Tamura, Hiroki Kakita
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
BackgroundHypoxic-ischemic encephalopathy (HIE) has a high morbidity rate and involves severe neurologic deficits, including cerebral palsy. Therapeutic hypothermia (TH) has been shown to decrease the mortality rate and provide neuroprotection in inf
Publikováno v:
Respiratory Research
Respiratory Research, Vol 21, Iss 1, Pp 1-17 (2020)
Respiratory Research, Vol 21, Iss 1, Pp 1-17 (2020)
Background It is well known that ventilation with high volume or pressure may damage healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal models of acute lung injury. Melatonin exerts its beneficial effects by
Autor:
Holly T. Philpott, Jason J. McDougall
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Background Endocannabinoids are showing great promise as effective mediators for controlling joint inflammation and pain. One strategy that could be harnessed to promote endogenous cannabinoid function is to inhibit the enzymatic break down of endoca
Autor:
Yaqi Yin, Yu Cheng, Jieqing Gao, Linxi Zhang, Songyan Yu, Zhengyuan Gong, Yiming Mu, Bing Li, Jing Xue
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Background Long-term diabetes-associated complications are the major causes of morbidity and mortality in individuals with diabetes. These diabetic complications are closely linked to immune system activation along with chronic, non-resolving inflamm
Autor:
Yen-Mei Lee, Chien-Yi Yang, Hsin-Hsueh Shen, Pao-Yun Cheng, Shu-Ying Chen, Hong-Min Wu, Kwok-Keung Lam, Ching-Wen Kung
Publikováno v:
Journal of Biomedical Science
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Background Loss of ovarian function, as in menopause or after ovariectomy (OVX), is closely associated with obesity and white adipose tissue (WAT) inflammation. Estrogen replacement protects against postmenopausal obesity but increases the risks of c